This article is part of Pulmonology Advisor‘s coverage of the CHEST 2019 meeting, taking place in New Orleans, LA. Our staff will report on medical research related to asthma, COPD, critical care medicine, and more conducted by experts in the field. Check back regularly for more news from CHEST 2019.


NEW ORLEANS — Older patients with sleep apnea are more likely to receive home oxygen upon hospital discharge following chronic obstructive pulmonary disease (COPD) exacerbations, , according to research presented at the CHEST Annual Meeting, held October 19 to 23, 2019, in New Orleans, Louisiana.

Researchers performed a retrospective chart review of adult patients who were admitted to a community hospital for COPD exacerbation between January 2014 and January 2018. Patients with prior home oxygen use, patients who died, or patients who left against medical advice were excluded from the analysis. A matched case-control analysis was used to identify cases and controls.

Researchers matched 90 cases (discharged with home oxygen) with 550 control participants (discharged without home oxygen) based on age, gender, and length of hospital stay. Risk factors assessed included tobacco and marijuana use, body mass index, underlying pneumonia or influenza, oxygen saturation, left heart failure, interstitial lung disease, and asthma.

Among all potential risk factors, asthma and sleep apnea were statistically significant categorical variables (P <.04 and P <.0001, respectively), whereas length of stay and lowest oxygen saturation were statistically significant contiguous variables (P <.05 and P <.001, respectively).

Age and sleep apnea were significant variables (odds ratios 1.023 and 4.073; P =.04 and P <.0001), as shown by the results of a logistic regression model.

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“Our study demonstrates that advancing age and underlying sleep apnea might increase the possibility of patients getting discharged on [long-term oxygen therapy] when admitted for COPD exacerbations with no prior home oxygen use,” the researchers concluded.

Disclosure: One study author declared affiliations with the pharmaceutical industry. Please see the original reference for a full list of authors’ disclosures.

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Reference

Kaul M, Bemiss B, Joseph S, et al. Factors that may increase the odds of requiring home oxygen upon discharge in patients admitted for COPD exacerbation. Presented at: CHEST Annual Meeting 2019; October 19-23, 2019; New Orleans, LA. Abstract 428.Abstract 446A.