Patients with pulmonary hypertension and COPD appear to have a poorer prognosis than those with idiopathic pulmonary arterial hypertension.
Many of the prescribed antipseudomonal drugs for patients with community-acquired pneumonia are potentially unnecessary.
Study authors sought to determine whether hospital outcomes in childhood severe sepsis were influenced by race, ethnicity, or insurance status, which are proxies for socioeconomic positions.
The trial enrolled 511 adult participants across 47 hospital emergency departments in the United States who had at least 1 risk factor for severe COVID-19.
The approval was based on data from 3 randomized, placebo-controlled trials that included 245 adults with ES-SCLC.
The acceleration of the COVID-19 pandemic continues to stress health care systems and exacerbate disparities in many communities, highlighting the importance of identifying patients at elevated risk of severe disease for COVID-19 vaccine prioritization.
The EUA was based on data from the randomized, double-blind, placebo-controlled ENSEMBLE trial.
The NDA submission is based on data from the double-blind, placebo-controlled phase 3 studies, COUGH-1 and COUGH-2.