Raised D-Dimer Linked to Mortality in Black Individuals With COVID-19 Pneumonia
A NYC hospital study explored disease severity in Black individuals with COVID-19 pneumonia, using D-dimer as a surrogate marker.
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Dupilumab Improves Severe Asthma Outcomes, Regardless of Baseline OCS Dose
A post-hoc analysis of the VENTURE trial evaluated whether baseline oral corticosteroid dosage affected the efficacy of dupilumab in improving severe asthma outcomes.
Tezepelumab Improves Lung Function in Severe, Uncontrolled Asthma
NAVIGATOR trial results presented at CHEST 2021 show the effect of tezepelumab on peak expiratory flow rates in severe asthma.
Efficacy and Safety of Gefapixant for Refractory/Unexplained Chronic Cough
Researchers conducted pooled analysis of the COUGH-1 and COUGH-2 phase 3 trials of gefapixant for treating refractory/unexplained chronic cough.
Nebulized Revefenacin for COPD Appears More Effective in Women vs Men
Researchers conducted subgroup analysis of revenfenacin phase 3 trial data to assess health status improvements in women vs men with moderate to severe COPD.
Inhaled Treprostinil and Lung Function in Patients With PH-ILD and PAH
A post-hoc analysis compared lung function changes in the INCREASE and TRIUMPH trials of inhaled treprostinil for PH-ILD and PAH.
Cyclophosphamide Not Recommended for Acute Exacerbation of Pulmonary Fibrosis
A clinical trial disproved the notion that adding cyclophosphamide pulses to glucocorticoids was effective for acute exacerbation of IPF.
Adenovirus Pneumonia CT Patterns in Adults Who Are Immunocompromised
What can be learned from temporal CT patterns of adenovirus pneumonia in immunocompromised patients?
Cytokine Clusters and Immunity Profiles Associated With Disease Severity in Children With SARS-CoV-2 Infection
Investigators conducted a study that compared serum cytokine concentrations and differences in immunity profiles in children hospitalized with SARS-CoV-2 infection.
Nurse-Led Program Boosts Medication Adherence Discussions
A single-session, nurse-led clinic staff education program on medication adherence leads to increased knowledge and practice changes at a FQHC.
Reboxetine, Oxybutynin Combination Shows Promise for Obstructive Sleep Apnea
A small study examined whether 1 week of combined reboxetine and oxybutynin treatment could reduce OSA severity.
Communication Interventions at Hospital Discharge Lowered Readmissions
Researchers examined existing data on the value of patient education at hospital discharge to determine its effect on outcomes.
Higher Risk for Mortality and Poor Outcomes Among Patients With SLE Hospitalized With COVID-19-Associated ARDS
Researchers assessed the risk for mortality and poor outcomes in patients with systemic lupus erythematosus hospitalized with COVID-19 acute respiratory distress syndrome.
Corticosteroid Responsiveness Assessed in Patients with Chronic Cough
The most common presenting complaints included shortness of breath, rhinorrhea, and hoarseness.
Triple Therapy Reduces Severe Asthma Exacerbations, Improves Lung Function
A recent meta-analysis of RCTs evaluated the efficacy and safety of ICS/LABA/LAMA fixed-dose combination asthma therapy with varying ICS dosages.
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