Post-ICU Syndrome: Identifying Challenges and Improving Mortality
Post-ICU syndrome includes psychological effects — depression, anxiety, and PTSD — as well as worsened physical functioning.
Critical Care
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Proposed Palliative Care Response Plans During the COVID-19 Pandemic
Clinicians have proposed a system-wide response plan for the delivery of high-quality palliative care across a continuum of conventional, contingency, and crisis capacity scenarios during the COVID-19 pandemic.
Should Asthma Care Shift Away From Control and Severity Steps?
Despite significant advances in asthma treatment in the past decades, the disease is still poorly controlled in an estimated 50% of patients.
Asthma, COPD Inhaler Medication Adherence Trends During COVID-19
Patients with asthma and COPD appear to have increased their adherence to inhaler medications in the wake of the COVID-19 pandemic.
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Fluid and Vasopressor Resuscitation Improves Sepsis-Associated Hypotension
The use of physiologically informed fluid and vasopressor resuscitation with passive leg raise–induced stroke volume change is safe for guiding the personalized management of sepsis-associated hypotension and shock.
FDA Issues EUA for Critical Med Needed for Ventilating Patients With COVID-19
The FDA has issued an EUA to allow for the use of Propoven 2% Emulsion 100mL to maintain sedation via continuous infusion in patients who require mechanical ventilation in an ICU setting during the COVID-19 pandemic.
Examining the Association Between Septic Shock Mortality and Early Antibiotic Use
Patients with septic shock who were administered antibiotics within an hour of onset had decreased in-hospital mortality rates.
OSA Does Not Appear to Be Associated With Postoperative Delirium in ICU
No association existed between obstructive sleep apnea and postoperative delirium after risk adjustment in the context of usual care in the intensive care unit.
Ready-to-Use Ephedrine Injection Gets FDA Approval
The FDA approved the New Drug Application (NDA) for Emerphed (Nexus Pharmaceuticals), a premixed, ready-to-use formulation of ephedrine sulfate.
HAT Therapy in Sepsis May Reduce Time to Resolution of Shock
In patients who are admitted to the ICU for the management of sepsis, the coadministration of hydrocortisone, ascorbic acid, and thiamine was safe and reduced the time to resolution of shock.
Adjunctive Therapy Use in Acute Respiratory Distress Syndrome Is Inconsistent
The Patient-Reported Outcomes Measurement Information System (PROMIS) assessing physical function and pain interference with computer adaptive tests offers a streamlined, effective approach for measuring self-reported outcomes in patients with chronic low back pain.
Sedation Plan Does Not Affect Mortality in Patients Receiving Mechanical Ventilation
Mortality did not differ significantly between patients assigned to no sedation and patients assigned to light sedation with daily interruption in the intensive care unit.
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