The Patient-Reported Outcomes Measurement Information System (PROMIS) assessing physical function and pain interference with computer adaptive tests offers a streamlined, effective approach for measuring self-reported outcomes in patients with chronic low back pain.
Mortality did not differ significantly between patients assigned to no sedation and patients assigned to light sedation with daily interruption in the intensive care unit.
In patients aged 65 years or older receiving vasopressors for vasodilatory hypotension, the use of permissive hypotension did not reduce all-cause 90-day mortality.
In-hospital mortality rates among patients requiring mechanical ventilation were not significantly different when comparing 2 stress ulcer prophylaxis strategies: proton pump inhibitors vs histamine-2 receptor blockers.
Prescribing positive airway pressure at hospital discharge was associated with reduced mortality after acute-on-chronic hypercapnic respiratory failure in patients with confirmed or suspected obesity hypoventilation syndrome.
In critically ill patients who were mechanically ventilated, variation in lung microbiota at admission predicted intensive care unit outcomes.
For patients with septic shock, treatment with intravenous vitamin C, hydrocortisone, and thiamine did not significantly improve the duration of survival and free of vasopressor administration over 7 days.
The FDA has issued a safety communication informing healthcare providers, facilities, and patients about cybersecurity vulnerabilities associated with certain GE Healthcare Clinical Information Central Stations and Telemetry Servers.