Influenza

Overcoming Challenges to Create a Universal Influenza Vaccine

By

Jasenka Piljac Žegarac, PhD

Researchers from the National Institute of Allergy and Infectious Diseases are working to develop a universal influenza vaccine.

Safety and Efficacy: IV Zanamivir vs Oral Oseltamivir in Severe Influenza

By

Cindy Lampner

Intravenous zanamivir is as safe and effective as oral oseltamivir when used in patients with severe influenza.

Symptom-Based Case Definitions for Detecting Influenza in Pregnant Women

By

Bradley van Paridon

Study authors evaluated the performance of symptom-based definitions to detect influenza in a cohort of pregnant women in India, Peru, and Thailand.

Pneumococcal Colonization Exacerbated by Influenza-Like Illness

By

Zahra Masoud

Researchers investigated the effects of ILI on pneumococcal carriage in community-dwelling older adults.

Antenatal Influenza Associated With Late Pregnancy Loss and Low Birthweight

By

Sweta Gupta

Investigators quantified the risk of antenatal influenza and examined its association with perinatal outcomes.

Age-Related Priming Determined Breadth of Influenza A(H3N2) Antibody Landscape in Children

By

Sweta Gupta

Researchers assessed whether pre-existing antibodies to influenza, which are shaped by early infection and subsequent exposures, impact children’s responses to influenza vaccination.

Influenza Vaccination Does Not Increase Risk for Guillain-Barré Syndrome

By

Zahra Masoud

Study authors identified and evaluated a statistical signal for an increased risk of Guillain-Barré Syndrome in days 1-42 after 2018-2019 high-dose influenza vaccine administration.

Baloxavir Marboxil Approved for Postexposure Prophylaxis of Influenza

By

Brian Park, PharmD

The approval was supported by data from the randomized, double-blind, placebo-controlled phase 3 Blockstone trial.

High-Dose Flu Vaccine More Effective for Patients With HIV

By

Bradley van Paridon

Study authors assessed the effectiveness of high-dose influenza vaccines in patients with HIV during the 2017-2018 influenza season.

Egg- And Cell-Derived Influenza Vaccines Elicit Similar Antibody Responses

By

Zahra Masoud

Investigators conducted a randomized, open-label trial during the 2018-2019 influenza season to assess neutralization titers in pre- and post-immunization sera from 133 adults immunized with one of three types of influenza vaccines.