HealthDay News — Oseltamivir does not appear to be associated with suicide risk in pediatric patients, according to a study published in the Annals of Family Medicine.

Rachel Harrington, from the University of Illinois at Chicago College of Pharmacy, and colleagues used a national administrative claims database and a case-crossover design to examine data from five influenza seasons (2009 to 2013) for 1- to 18-year-olds.

The authors examined exposure to oseltamavir and assessed the correlation between oseltamavir use and suicide.

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The researchers identified 21,407 suicide-related events during the study period, including 251 in oseltamivir-exposed children. There was no significant correlation with suicide for oseltamavir exposure (odds ratio, 0.64; 95% CI, 0.39-1.00; P =.05) or for influenza diagnosis alone (odds ratio, 0.63; 95% CI, 0.34-1.08; P =.1) in case-crossover analysis.

“Our findings suggest that oseltamivir does not increase risk of suicide in the pediatric population,” the authors wrote.

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Harrington R, Adimadhyam S, Lee TA, Schumock GT, Antoon JW. The relationship between oseltamivir and suicide in pediatric patients.  Ann Fam Med. 2018; 16(2): 145-148.