Lung Infection

Study to Examine Efficacy of Canakinumab in COVID-19 With Acute Myocardial Injury

By

Jessica Nye, PhD

Publish Date September 18, 2020

Recruitment has begun for study examining the efficacy of canakinumab for the treatment of patients with COVID-19 and acute myocardial injury.

COVID-19: Assessing Antibody Responses and Clinical Outcomes in Severe Disease

By

Bradley van Paridon

Publish Date September 18, 2020

Levels of immunoglobulin G antibodies against nucleocapsid, the spike protein, and the receptor binding domain were related to viral clearance.

Icatibant Treatment Improves Oxygenation in COVID-19 Patients

By

Zahra Masoud

Publish Date September 18, 2020

Icatibant, a bradykinin 2 receptor antagonist, may improve oxygenation in patients with coronavirus disease 2019 (COVID-19).

Baricitinib Plus Remdesivir Shortens Recovery Time for Hospitalized Patients With COVID-19

By

Brian Park, PharmD

Publish Date September 17, 2020

The ACTT-2 study began on May 8 and included more than 1000 patients.

Young Adults With COVID-19 Have Substantial Rates of Adverse Outcomes

Publish Date September 17, 2020

Young adults hospitalized with COVID-19 have substantial rates of adverse outcomes.

COVID-19 Vaccines: AstraZeneca Resumes Trial; Pfizer, BioNTech Look to Expand Study

By

Diana Ernst, RPh

Publish Date September 16, 2020

The Medicines Health Regulatory Authority confirmed that the AZD1222 trial could proceed after a UK committee concluded its investigations.

COVID-19, SARS-CoV-2 Infection Phenotypes Vary With Different Tumor Subtypes

By

Rita Aghjayan

Publish Date September 16, 2020

Among patients with cancer, tumor subtypes may influence varying susceptibility to SARS-CoV-2 and COVID-19 disease phenotypes.

Potential Role for Extracorporeal Membrane Oxygenation Support in Severe COVID-19

By

Bryant Moeller

Publish Date September 14, 2020

Critically ill patients with severe coronavirus disease 2019 may benefit from extracorporeal membrane oxygenation therapy.

Sensitivity of 3 ICT Assays Higher During Intermediate, Late COVID-19 Stages

By

Sweta Gupta

Publish Date September 14, 2020

Researchers compared 3 immunochromatographic assays (Sienna™, Wondfo®, and Prometheus™) to detect antibodies against SARS-CoV-2 in serum samples, using RT-qPCR as a reference.

Statistically Significant Reduction in Cough Frequency Observed in Gefapixant Trials

By

Brian Park, PharmD

Publish Date September 14, 2020

The double-blind, placebo-controlled studies, COUGH-1 and COUGH-2, included 730 and 1314 adult patients with refractory or unexplained chronic cough for at least 1 year, respectively.

Factor V Activity Associated With Clinical Outcomes in Severe COVID-19

By

Lauren Dembeck, PhD

Publish Date September 14, 2020

Investigators assess underlying mechanisms and relevant biomarkers of morbidity and mortality due to coagulopathy in patients with severe COVID-19 infection.