In patients hospitalized with coronavirus disease 2019 (COVID-19) in the New York City area, the most common comorbidities were hypertension, obesity, and diabetes, according to findings published in JAMA.
Limited information is available on the presenting characteristics and outcomes of patients in the United States requiring hospitalization with COVID-19. Therefore, researchers conducted a case series of 5700 sequentially hospitalized patients with COVID-19 admitted to 12 hospitals in New York City, Long Island, and Westchester County, New York from March 1, 2020 to April 4, 2020.
The median age of these patients was 63 years and 60.3% were men. The most common comorbidities were hypertension (56.6%), obesity (41.7%), and diabetes (33.8%). Outcomes were assessed for 2634 patients who were discharged or had died at the study end point, and researchers found that during hospitalization, 14.2% were treated in the intensive care unit, 12.2% required invasive mechanical ventilation, 3.2% received kidney replacement therapy, and 21% died. In patients who required mechanical ventilation (n=1151; 20.2%), 3.3% were discharged alive, 24.5% died, and 72.2% remained in the hospital as of April 4, 2020. The median postdischarge follow-up time was 4.4 days, and 2.2% of patients were readmitted during the study period.
“To our knowledge, this study represents the first large case series of sequentially hospitalized patients with confirmed COVID-19 in the US,” the researchers concluded. “Older persons, men, and those with preexisting hypertension and/or diabetes were highly prevalent in this case series and the pattern was similar to data reported from China.”
Disclosure: Several study authors declared affiliations with the pharmaceutical industry. Please see the original reference for a full list of authors’ disclosures.
Richardson S, Hirsch JS, Narasimhan M, et al; on behalf of the Northwell COVID-19 Research Consortium. Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City Area [published online April 22, 2020]. JAMA. doi:10.1001/jama.2020.6775