Obstructive Lung Disease

Is There an “Ideal” Cystic Fibrosis Candidate for Lung Transplantation?

By

Suzanne Bujara

Publish Date August 23, 2018

Lung transplantation can extend survival in patients with cystic fibrosis who have compromised lung function and increasing exacerbations.

Tobacco Smoke Exposure Limits Benefits of CFTR Modulators in Cystic Fibrosis

By

Britt Gambino

Publish Date May 20, 2020

Tobacco smoke exposure inhibited the therapeutic benefit of the cystic fibrosis transmembrane conductance regulator modulators in pediatric patients.

Lumacaftor-Ivacaftor May Improve Glucose Tolerance in Cystic Fibrosis

By

Bryant Moeller

Publish Date April 15, 2020

Patients with cystic fibrosis who were treated for 1 year with a combination of lumacaftor and ivacaftor saw improvements in glucose tolerance abnormalities

Inhaled Messenger RNA Treatment Fast-Tracked for Cystic Fibrosis

By

Steve Duffy

Publish Date March 9, 2020

The FDA has granted Fast Track designation to MRT5005, an inhaled messenger RNA (mRNA) therapeutic being investigated for the treatment of cystic fibrosis.

Ultrasound May Identify Children at Risk for Cystic Fibrosis Liver Disease

Publish Date February 27, 2020

A heterogeneous liver pattern could indicate a higher risk for advanced cystic fibrosis liver disease.

Investigational Antibiotic Receives Orphan Drug Status for CF Pulmonary Exacerbations

By

Steve Duffy

Publish Date February 26, 2020

The FDA has granted Orphan Drug designation to ARV-1801 (sodium fusidate; Arrevus) for the treatment of pulmonary exacerbations in patients with cystic fibrosis.

Continuous Glucose Monitoring in Youth With Cystic Fibrosis May Detect Early Diabetes

By

Pulmonology Advisor Contributing Writer

Publish Date February 3, 2020

Continuous glucose monitoring may provide a better understanding of the early stages of diabetes progression in youth with cystic fibrosis.

Nontuberculous Mycobacterial Infection in Cystic Fibrosis: Treatment Recommendations

By

Brandon May

Publish Date January 13, 2020

A multidisciplinary team discussed exploring the management options for nontuberculous mycobacterial infection in patients with cystic fibrosis.

Differences in BAL Surveillance of Preschool Children With Cystic Fibrosis

By

Sheila Jacobs

Publish Date December 17, 2019

Significant differences have been observed from bronchoalveolar lavage surveillance conducted among preschool children with cystic fibrosis, according to their country of residence.