Common comorbidities in OSA such as cardiovascular disease and metabolic abnormalities, may confer a higher risk for the development of mental and cognitive impairment in patients with OSA compared with the general population.
A panel of 4 clinicians with experience in pediatric pulmonology discuss current research findings and gaps in studies of pediatric obstructive sleep apnea, particularly regarding cardiovascular risk.
In patients with obstructive sleep apnea with residual sleepiness, the use of pitolisant as an adjunct to CPAP therapy significantly decreases subjective and objective sleepiness.