The 6th WSPH Task Force on Hemodynamic Definitions and Clinical Classification recently proposed reducing the diagnostic mPAP threshold for pulmonary hypertension.
PAH associated with CHD is linked to significant reductions in survival and quality of life, especially for patients progressing to Eisenmenger syndrome.
Although pulmonary hypertension as a result of interstitial lung disease is linked to significant morbidity and mortality, there is no consensus regarding screening or management of the disease.
Emerging evidence suggests that the extrapulmonary effects of pulmonary arterial hypertension may manifest in the form of vascular dysfunction in systemic circulation, metabolic/endocrine dysfunction, and skeletal and respiratory muscle dysfunction.
Since uric acid levels in patients with idiopathic pulmonary arterial hypertension are associated with an impaired clinical and hemodynamic profile, they may serve as a useful noninvasive indicator of disease severity.
In pulmonary arterial hypertension, high plasma levels of hepatic growth factor are associated with the right heart maladaptive phenotype and are incremental to the REVEAL score for the prediction of patient outcomes.
Patients with pulmonary hypertension caused by interstitial lung disease experienced greater improvements in exercise capacity with inhaled treprostinil compared with placebo.
The new diagnostic criteria for pre-capillary pulmonary hypertension may better recognize patients with early forms of pulmonary vascular disease and poor prognosis.
Compared with women, men with HFpEF have been shown to be more compromised with respect to dynamic right ventricle-pulmonary artery uncoupling and reduced VO2.
A collection of algorithms for detecting pulmonary arterial hypertension in administrative data has been developed to enhance the integrity and value of research findings and improve quality of care.
Patients with pulmonary arterial hypertension (PAH) who were treated with treprostinil using an implantable infusion pump experienced few serious complications.
