The novel Fujifilm SILVAMP TB LAM assay offers superior diagnostic sensitivity while also maintaining specificity, compared with standard assay.
In patients who are immunocompromised, such as people living with HIV, the new fourth-generation QuantiFERON-TB Gold Plus assay demonstrated similar sensitivity to the third-generation interferon-gamma release assay for the diagnosis of latent tuberculosis.
The CDC announced an expected 3 to 10 month shortage of Aplisol used as an aid in the diagnosis of tuberculosis.
The FDA’s Antimicrobial Drugs Advisory Committee voted in favor of pretomanid, as part of a combination regimen with bedaquiline and linezolid, for the treatment of pulmonary extensively drug resistant, treatment intolerant, or nonresponsive multidrug resistant tuberculosis.
Researchers reported a case of drug resistance against 2 recently approved antitubercular medications: delamanid and bedaquiline.
For prevention of TB in people with HIV, a single month regimen of rifapentine plus isoniazid was noninferior to 9 months of isoniazid alone.
Number of tuberculosis cases and incidence decreased globally, but more progress is needed to meet targets.
The new interferon-gamma release assay QuantiFERON-TB Gold Plus had good sensitivity in children with pulmonary tuberculosis.