Investigators examined whether influenza is an independent risk factor for the development of acute myocardial infarction.
Seasonal influenza activity was also found to be low in the Southern Hemisphere.
The CHEST Expert Cough Panel agreed on cough, dyspnea, pleural pain, sweating, shivers, aches, temperature of ≥38°C, tachypnea, and new and localizing chest examination signs as clinical symptoms as criteria suggestive of pneumonia in outpatient adults.
To better understand the influence of prior-season vaccination on subsequent influenza vaccine effectiveness, researchers conducted a multiseason, test-negative case-control study among vaccinated children 2-17 years old recruited during 3 influenza seasons (2013-2014, 2014-2015, and 2015-2016).
Time-series analysis based on geographic location revealed positive significant associations between asthma and influenza hospitalizations in Brooklyn and Manhattan.
The FDA has approved the use of Afluria and Afluria Quadrivalent for use in patients ≥6 months old.
"This is the first new antiviral flu treatment with a novel mechanism of action approved by the FDA in nearly 20 years," said FDA Commissioner Scott Gottlieb, MD.
There were reductions in influenza cases, deaths, and costs by adding pharmacies during influenza epidemics.
Fewer than half of women who were pregnant during peak influenza vaccination period in 2017 to 2018 were vaccinated.
Larger cities with higher base transmission potentials have more diffuse influenza epidemics.
Influenza-related hospitalizations were reduced by 40% over 6 flu seasons.
Repeated exposure to the influenza virus affects antibody quantity and quality, and strains selected for seasonal vaccines may not provide coverage sufficient for individuals frequently infected and/or vaccinated.
Elderly patients who have been inoculated with the influenza vaccine and who also use a statin are at a greater risk for medically attended acute respiratory illness.
NasoVAX, an adenovirus-based intranasal flu vaccine, shows tolerability, safety, and higher cellular immune response compared to an injectable vaccine.
When compared to placebo, baloxavir marboxil was associated with reduced risk of influenza complications and faster recovery.
Active Choice Intervention Effective in Increasing Influenza Vaccination Rates at Primary Care Practices
Influenza vaccination rates decline as the clinic day progresses.
Patients with acute respiratory distress syndrome and confirmed influenza diagnosis treated ≤6 hours with oseltamivir had reduced length of hospital stay and a lower rate of mortality.
Wide variations in influenza vaccine coverage have been noted across healthcare personnel based on occupation and worksite.
The 2017 to 2018 flu strains hit the very young and elderly especially hard.
Mandatory genetic testing may also constitute an undue threat to employee autonomy and privacy.
Vaccination rates decreased throughout the day; with intervention, there was a similar increase throughout day.
New York City health officials say passengers had influenza or other common cold viruses.
Corticosteroids should not be used concomitantly with antiviral therapy in patients with influenza pneumonia.
According to the Centers for Disease Control and Prevention (CDC), the 2017-2018 flu season was one of the most severe - excluding pandemics - on record.
Baloxavir had a median time to alleviation of symptoms vs placebo, and a similar alleviation time as oseltamivir.
Influenza proved to be an independent risk factor for invasive pulmonary aspergillosis.
In general, routine annual vaccination is recommended for all patients ≥6 months of age who have no contraindications.
Hospitalization risk was also reduced for RA patients who received influenza vaccination.
Inappropriate antibiotic prescriptions were highest among urgent care facilities (45.7%), with emergency departments (24.6%), medical offices (17.0%), and retail clinics (14.4%) following.
Immune priming with seasonal H1N1 viruses earlier in life and egg-adaptation in vaccines can impact antibody responses following influenza vaccination.
Most children who died of pneumococcus and Haemophilus influenzae type b presented with pneumonia.
The New Drug Application for baloxavir marboxil is supported by results from the Phase 3 CAPSTONE-1 study (N=1436) which examined the effects of a single dose of baloxavir marboxil vs placebo or oseltamivir 75mg twice daily for 5 days.
Respiratory pathogens were associated with an increased risk for treatment failure in children with asthma exacerbations.
The researchers argued that outpatient antibiotic stewardship efforts must be strengthened to eliminate antibiotic treatment for viral upper respiratory infections and acute bronchitis.
The advisory comes early as physicians are currently placing vaccine orders.
A high impact was seen, especially when the vaccine uptake was optimally distributed across age groups.
This updated Committee Opinion includes more recent data on the safety and efficacy of influenza vaccination during pregnancy, as well as recommendations for treatment and postexposure chemoprophylaxis.
Adult caretaker influenza vaccination cocooning programs can prove beneficial and financially successful in private practice models where external funding is limited or not available.
During the cold and flu season, the use and over-dosing of paracetamol is common, and may partially be driven by higher use of over-the-counter combination medications for the treatment of upper respiratory cold/flu symptoms.
Among children there was an increased risk for acute respiratory illness caused by noninfluenza respiratory pathogens following influenza vaccination compared to unvaccinated children during the same period.
Researchers found increased myocardial infarction rates during the week after Streptococcus pneumoniae and influenza infections.
Higher serum bactericidal activity following immunization with PRP-CRM197 reflected superior short-term and long-term seroprotective effects compared with immunization with PRP-T.
Immunogenicity of RIV4 similar to that of inactivated vaccine, although responses to B Victoria were low with both.
Further research on rapid tests is warranted, as industry-sponsored research tends to favor the industry's product and affects how physicians practice medicine.
Despite 8 of the 10 flights taking place during influenza season, results of quantitative polymerase chain reaction assays for 18 common respiratory viruses were all negative.
There was no significant correlation with suicide for oseltamavir exposure or for influenza diagnosis alone.
Acetaminophen use and overdosing increases during cold and flu season.
The CDC's ACIP has voted in favor of renewing the recommendation for the use of live attenuated influenza vaccine.
Cardiac surgery during influenza season is an independent risk factor for acute respiratory distress syndrome.
Investigators sought to determine the association between maternal vaccination and infant mortality.
Influenza A viruses have predominated the 2017 to 2018 season with a vaccine effectiveness between 25% and 67%.
Airborne influenza viruses may be safely and effectively eradicated with continuous low doses of far ultraviolet C light.
The recommended childhood and adolescent immunization schedule for the United States has been issued for 2018.
Patients who received provider-ordered influenza testing were more likely to be younger and present with fever and "influenza-like illness."
Influenza increased the risk for acute myocardial infarction within 1 year before and 1 year after the infection.
Patient reminder and recall systems seem to be effective for improving receipt of immunizations.
Researchers from the National Institute of Allergy and Infectious Diseases are working to develop a universal influenza vaccine.
Vaccination for influenza for multiple seasons is twice as effective in preventing severe influenza.
Patients with an egg allergy do not need to avoid or take special precautions when receiving the influenza vaccine.
Educational campaigns regarding the value of vaccines should integrate social psychological considerations with health communication principles.
Midturbinate swabs for influenza detection provided a more comfortable experience for patients compared with traditional nasopharyngeal swabs.
Since the start of November 2017, influenza activity has increased in the United States.
A glycoprotein mutation in fertilized chicken eggs may be the cause of the limited effectiveness of the 2016-2017 flu vaccine.
About 50 employees have been fired from Essentia Health, a Duluth, Minnesota-based hospital chain, for refusing to receive the flu vaccination.
Interventions to target healthcare professional-associated influenza transmission, intervention may be necessary to prevent transmission.
Antipyretic administration for fever in young children is not associated with any significant blunting of immune response to inactivated influenza vaccination.
Text messaging may be an effective way to increase the rate of influenza vaccination.
Influenza vaccination in the pediatric emergency department setting appears to be a cost-effective strategy.
Temporary discontinuation of methotrexate after influenza vaccination is associated with improved immunogenicity of vaccination in RA.
A highly pathogenic variant of H7N9 avian influenza has evolved and is now capable of causing a pandemic, according to recent research.
Rapivab is now indicated for use in pediatric patients ≥2 years with acute uncomplicated influenza.
Despite the loss of the live attenuated influenza vaccine, overall immunization rates in children 2-17 remained steady.
The majority of healthcare workers receive an influenza vaccination, but more pregnant women should be vaccinated.
The CDC continues to urge pregnant women to receive influenza vaccinations.
Influenza vaccination does not increase the risk for venous thromboembolism in patients older than 50 years of age.
Influenza vaccine in the prior season did not decrease the efficacy of the current season's vaccine.
The American Academy of Pediatrics recommends against the use of the quadrivalent live attenuated influenza vaccine (LAIV4).
Researchers examined the efficacy of digital immunoassays vs rapid influenza diagnostic tests for diagnosing influenza.
Fewer children were immunized against influenza once the CDC ruled out use of the nasal spray.
Hospitalization risk was increased in infants of vaccinated vs nonvaccinated mothers only during the first 90 days of life.
The influenza A virus in swine was transmitted to humans at state fairs in Ohio and Michigan.
The Advisory Committee on Immunization Practices (ACIP) has issued the 2017-2018 influenza vaccination guidelines.
The rs34481144 risk allele may serve as a genetic marker for identifying individuals at increased risk for severe influenza infection.
Data from the 2015-2016 season shows that the live attenuated influenza vaccine was ineffective among children ages 2-17.
Influenza and pulmonary-related hospitalizations were lower in elderly patients who received the high-dose trivalent influenza vaccine vs the standard dose.
Increasing Vitamin D supplements does not prevent winter upper respiratory tract infections in young healthy children.
Influenza vaccination provided a small protective effect in patients with asthma.
Vaccinations include Fluad, Flucelvax Quadrivalent, Afluria Quadrivalent, and Fluvirin,
During the 2015-2016 flu season, approximately 59.3% of children and 41.7% of adults received the influenza vaccine.
The 2016-2017 flu season is the first time since 2014-2015 that pediatric influenza-associated deaths have surpassed 100.
Researchers assessed the relative risk for developing influenza or influenza-like illness based on study participants BMI.
Right-sided abdominal pain, vomitting, fever, and mild diarrhea were all present in a 66-year-old woman with a history of sarcoidosis and hypertension.
Immunogenicity of 4 different vaccine strains, including H1N1, H3N2, and B influenza, were examined.
Videotapes of 50 visits were examined to determine whether clinician pursuit of influenza vaccine affected vaccination rates in pediatric patients.
Over 2278 health subjects were included in a multicenter study of the Seqirus IIV4 quadrivalent inactivated influenza vaccine.
Molecular point-of-care testing for viruses led to more patients receiving single or brief doses of antibiotics without any evidence of increased harm.
A new study found no risks for exacerbation of asthma in children given LAIV, despite ACIP recommendations against its use in children with asthma.
The inactivated monovalent influenza A(H1N1) vacccines in both adjuvanted and unadjuvanted forms were more effective in children than adults.
Birth weight and week's gestation of infants at birth are not affected by maternal influenza vaccination during any trimester of pregnancy.
Intravenous zanamivir is as safe and effective as oral oseltamivir when used in patients with severe influenza.