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Overcoming Challenges to Create a Universal Influenza Vaccine

Overcoming Challenges to Create a Universal Influenza Vaccine

Researchers from the National Institute of Allergy and Infectious Diseases are working to develop a universal influenza vaccine.

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Flu Vaccine Reduces Mortality in Rheumatoid Arthritis

Flu Vaccine Reduces Mortality in Rheumatoid Arthritis

Hospitalization risk was also reduced for RA patients who received influenza vaccination.

Inappropriate Antibiotic Prescriptions Highest Among Urgent Care Facilities

Inappropriate Antibiotic Prescriptions Highest Among Urgent Care Facilities

Inappropriate antibiotic prescriptions were highest among urgent care facilities (45.7%), with emergency departments (24.6%), medical offices (17.0%), and retail clinics (14.4%) following.

H1N1 Immune Priming and Egg-Adaptation Affect Antibody Responses After Vaccination

H1N1 Immune Priming and Egg-Adaptation Affect Antibody Responses After Vaccination

Immune priming with seasonal H1N1 viruses earlier in life and egg-adaptation in vaccines can impact antibody responses following influenza vaccination.

Drop in Childhood Pneumococcal, Hib Deaths From 2000 to 2015

Drop in Childhood Pneumococcal, Hib Deaths From 2000 to 2015

Most children who died of pneumococcus and Haemophilus influenzae type b presented with pneumonia.

Priority Review Granted to Novel Oral Influenza Treatment

Priority Review Granted to Novel Oral Influenza Treatment

The New Drug Application for baloxavir marboxil is supported by results from the Phase 3 CAPSTONE-1 study (N=1436) which examined the effects of a single dose of baloxavir marboxil vs placebo or oseltamivir 75mg twice daily for 5 days.

Respiratory Viruses Linked to Treatment Failure in Asthma Exacerbations

Respiratory Viruses Linked to Treatment Failure in Asthma Exacerbations

Respiratory pathogens were associated with an increased risk for treatment failure in children with asthma exacerbations.

Misuse of Antibiotics Common in Outpatient Acute Respiratory Infections

Misuse of Antibiotics Common in Outpatient Acute Respiratory Infections

The researchers argued that outpatient antibiotic stewardship efforts must be strengthened to eliminate antibiotic treatment for viral upper respiratory infections and acute bronchitis.

AAP Recommends Shot Over Nasal Spray for 2018-2019 Flu Season

AAP Recommends Shot Over Nasal Spray for 2018-2019 Flu Season

The advisory comes early as physicians are currently placing vaccine orders.

Flu Vaccines Have High Impact, Even With Relatively Low Efficacy

Flu Vaccines Have High Impact, Even With Relatively Low Efficacy

A high impact was seen, especially when the vaccine uptake was optimally distributed across age groups.

ACOG: Updated Recommendations for Influenza Vaccination During Pregnancy

ACOG: Updated Recommendations for Influenza Vaccination During Pregnancy

This updated Committee Opinion includes more recent data on the safety and efficacy of influenza vaccination during pregnancy, as well as recommendations for treatment and postexposure chemoprophylaxis.

Adult Caregivers Likely to Receive Influenza Vaccination From Pediatric Clinics

Adult Caregivers Likely to Receive Influenza Vaccination From Pediatric Clinics

Adult caretaker influenza vaccination cocooning programs can prove beneficial and financially successful in private practice models where external funding is limited or not available.

Paracetamol Overuse During Cold and Flu Season

Paracetamol Overuse During Cold and Flu Season

During the cold and flu season, the use and over-dosing of paracetamol is common, and may partially be driven by higher use of over-the-counter combination medications for the treatment of upper respiratory cold/flu symptoms.

Increased Risk for Acute Respiratory Illness Following Influenza Vaccine in Children

Increased Risk for Acute Respiratory Illness Following Influenza Vaccine in Children

Among children there was an increased risk for acute respiratory illness caused by noninfluenza respiratory pathogens following influenza vaccination compared to unvaccinated children during the same period.

Pneumonia and Influenza May Trigger Acute MI, Stroke

Pneumonia and Influenza May Trigger Acute MI, Stroke

Researchers found increased myocardial infarction rates during the week after Streptococcus pneumoniae and influenza infections.

Prevention of Vaccine Failure in Haemophilus influenzae Type B Vaccines

Prevention of Vaccine Failure in Haemophilus influenzae Type B Vaccines

Higher serum bactericidal activity following immunization with PRP-CRM197 reflected superior short-term and long-term seroprotective effects compared with immunization with PRP-T.

Recombinant Influenza Vaccine Found to Be Safe in Children

Recombinant Influenza Vaccine Found to Be Safe in Children

Immunogenicity of RIV4 similar to that of inactivated vaccine, although responses to B Victoria were low with both.

Newer Rapid Influenza Tests Better at Ruling In Influenza

Newer Rapid Influenza Tests Better at Ruling In Influenza

Further research on rapid tests is warranted, as industry-sponsored research tends to favor the industry's product and affects how physicians practice medicine.

Influenza, Other Respiratory Disease Transmission During Flights

Influenza, Other Respiratory Disease Transmission During Flights

Despite 8 of the 10 flights taking place during influenza season, results of quantitative polymerase chain reaction assays for 18 common respiratory viruses were all negative.

Suicide Risk Not Increased With Oseltamivir in Pediatric Patients

Suicide Risk Not Increased With Oseltamivir in Pediatric Patients

There was no significant correlation with suicide for oseltamavir exposure or for influenza diagnosis alone.

Acetaminophen Use, Overdose May Increase During Flu Season

Acetaminophen Use, Overdose May Increase During Flu Season

Acetaminophen use and overdosing increases during cold and flu season.

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