Influenza

World Health Organization: Five-Year Plan to Address 10 Biggest Global Health Threats

World Health Organization: Five-Year Plan to Address 10 Biggest Global Health Threats

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In an effort to effectively address global health concerns, the WHO has announced the 13th General Programme of Work, a 5-year strategic plan spanning from 2019 to 2023.

AAP Releases 2019 Childhood Immunization Schedules

AAP Releases 2019 Childhood Immunization Schedules

Influenza row modified to reflect current recommendations for the live attenuated flu vaccine.

ACIP Updates Recommendations for US Adult Immunization Schedule

ACIP Updates Recommendations for US Adult Immunization Schedule

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The ACIP and CDC have approved and released 2019 recommendations for the adult immunization schedule in the United States.

Influenza-Like Illness Linked to Increased Risk for Stroke

Influenza-Like Illness Linked to Increased Risk for Stroke

The second study showed patients were more likely to have influenza-like illness within 30 days preceding cervical artery dissection.

New Dosing Option for Fluzone Quadrivalent in Children as Young as 6 Months

New Dosing Option for Fluzone Quadrivalent in Children as Young as 6 Months

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The approval was based on findings from a Phase 4 safety and immunogenicity study that included ~2000 children.

WHO: Vaccine Hesitancy a Major Global Health Threat

WHO: Vaccine Hesitancy a Major Global Health Threat

The percentage of American children aged 19 to 35 months who have not been vaccinated has quadrupled since 2001.

Bacterial Pneumonia-Complicating Influenza: Risks, Morbidity, and Mortality

Bacterial Pneumonia-Complicating Influenza: Risks, Morbidity, and Mortality

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Diagnosing coinfection in pneumonia can be challenging because of timing of the sample collection and false-negative results when the viruses replicate in the lower respiratory tract.

Women With H1N1 Influenza in ICU Have Higher Risk for Adverse Birth Outcomes

Women With H1N1 Influenza in ICU Have Higher Risk for Adverse Birth Outcomes

Pregnant women admitted to ICU with 2009 H1N1 influenza were more likely to deliver preterm and low birth-weight infants.

Point-of-Care Testing Methods Compared for Influenza Detection

Point-of-Care Testing Methods Compared for Influenza Detection

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Study authors aimed to assess the clinical impact of a POC PCR test (the Cobas LIAT Influenza A/B assay) for the diagnosis of influenza.

CDC: Influenza Cases Hit 7 Million in the United States

CDC: Influenza Cases Hit 7 Million in the United States

Half of these individuals went to a doctor, while 69,000 to 84,000 people have been hospitalized.

Flu Vaccination During Hospitalization Is Safe and Convenient, Says Study

Flu Vaccination During Hospitalization Is Safe and Convenient, Says Study

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To investigate the safety of influenza vaccination during hospitalization, researchers from Kaiser Permanente assessed the health records of >250,000 patients, 6 months of age and older, who were hospitalized during any of the 3 flu seasons from 2011 to 2014 and were admitted and discharged between September 1 and March 31.

Influenza Vaccine Cuts Flu-Related Hospitalization in COPD

Influenza Vaccine Cuts Flu-Related Hospitalization in COPD

Influenza-positive patients have higher rates of crude mortality and critical illness vs influenza-negative patients.

Live Flu Vaccine Less Effective Than Inactivated Vaccine in Children

Live Flu Vaccine Less Effective Than Inactivated Vaccine in Children

Quadrivalent live attenuated influenza vaccine less effective than inactivated vaccine for influenza A/H1N1pdm09.

Influenza Linked to Increased In-Hospital Mortality in Heart Failure

Influenza Linked to Increased In-Hospital Mortality in Heart Failure

In patients with heart failure, influenza infection is associated with increased in-hospital morbidity and mortality.

Severe Rhabdomyolysis in a Patient With Acute Influenza Infection

Severe Rhabdomyolysis in a Patient With Acute Influenza Infection

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The patient, who had a history significant for cerebral palsy, seizures, and chronic constipation, had presented complaining of 3 days of fever, nausea, vomiting, and anorexia.

Increased Risk of Hospitalization for Influenza When Morbidly Obese or Underweight

Increased Risk of Hospitalization for Influenza When Morbidly Obese or Underweight

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Adults with influenza were more likely to be hospitalized if they were underweight or morbidly obese compared with normal-weight adults.

Influenza Seroconversion Risk Factors in Adults Hospitalized for Pneumonia

Influenza Seroconversion Risk Factors in Adults Hospitalized for Pneumonia

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Adults hospitalized for pneumonia who received an influenza vaccination during their stay were less likely to seroconvert if they had diabetes, bacterial detection, baseline seropositive titers for influenza B, or influenza vaccination in the previous season.

Influenza Diagnosis and Treatment Guidelines Updated

Influenza Diagnosis and Treatment Guidelines Updated

Rapid molecular assays should be used to improve influenza diagnosis and antivirals should begin as soon as possible.

Racial Disparities Seen in Teenagers Undergoing Flu Vaccination

Racial Disparities Seen in Teenagers Undergoing Flu Vaccination

Black adolescents have lower odds of receiving influenza vaccination than white adolescents.

Antibody Response to Flu Vaccine Evaluated in Benralizumab-Treated Asthma

Antibody Response to Flu Vaccine Evaluated in Benralizumab-Treated Asthma

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The trial analyzed the antibody response of 103 asthmatic patients to the seasonal influenza vaccine.

Mortality With Influenza vs RSV Infection in Older, Hospitalized Adults

Mortality With Influenza vs RSV Infection in Older, Hospitalized Adults

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In older, hospitalized adults, respiratory syncytial virus may be associated with greater morbidity and mortality compared with influenza.

Culture Negative Pneumonia Rates Linked to Higher PM<sub>2.5</sub> Concentrations

Culture Negative Pneumonia Rates Linked to Higher PM2.5 Concentrations

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Increases in the relative rates of culture negative pneumonia that required hospitalization or emergency department visits were significantly associated with increased concentrations of fine particulate air pollution.

Annual Influenza Shots May Lower Risk of CV Death in Heart Failure

Annual Influenza Shots May Lower Risk of CV Death in Heart Failure

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A study published in Circulation has found a reduced risk of cardiovascular (CV) death in heart failure patients when they are given routine influenza vaccinations.

Influenza Vaccine Effectiveness Not Modified by Statin Use

Influenza Vaccine Effectiveness Not Modified by Statin Use

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Statin use did not modify the effect of vaccination on influenza in adults ≥45 years.

Influenza Infection Increases Mortality Risk in Acute Myocardial Infarction

Influenza Infection Increases Mortality Risk in Acute Myocardial Infarction

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Investigators examined whether influenza is an independent risk factor for the development of acute myocardial infarction.

Low Levels of Influenza Reported in the United States From May to October

Low Levels of Influenza Reported in the United States From May to October

Seasonal influenza activity was also found to be low in the Southern Hemisphere.

New CHEST Guideline for Acute Cough Due to Suspected Pneumonia or Influenza

New CHEST Guideline for Acute Cough Due to Suspected Pneumonia or Influenza

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The CHEST Expert Cough Panel agreed on cough, dyspnea, pleural pain, sweating, shivers, aches, temperature of ≥38°C, tachypnea, and new and localizing chest examination signs as clinical symptoms as criteria suggestive of pneumonia in outpatient adults.

Does Prior Flu Vaccination Affect Subsequent Vaccine Efficacy in Children?

Does Prior Flu Vaccination Affect Subsequent Vaccine Efficacy in Children?

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To better understand the influence of prior-season vaccination on subsequent influenza vaccine effectiveness, researchers conducted a multiseason, test-negative case-control study among vaccinated children 2-17 years old recruited during 3 influenza seasons (2013-2014, 2014-2015, and 2015-2016).

Are Asthma Hospitalizations Predictive of Influenza Hospitalizations in NYC Adults?

Are Asthma Hospitalizations Predictive of Influenza Hospitalizations in NYC Adults?

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Time-series analysis based on geographic location revealed positive significant associations between asthma and influenza hospitalizations in Brooklyn and Manhattan.

Trivalent, Quadrivalent Inactivated Influenza Vaccine Approved for Patients 6 Months and Older

Trivalent, Quadrivalent Inactivated Influenza Vaccine Approved for Patients 6 Months and Older

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The FDA has approved the use of Afluria and Afluria Quadrivalent for use in patients ≥6 months old.

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