Flu Vaccination During Hospitalization Is Safe and Convenient, Says Study

Flu Vaccination During Hospitalization Is Safe and Convenient, Says Study

To investigate the safety of influenza vaccination during hospitalization, researchers from Kaiser Permanente assessed the health records of >250,000 patients, 6 months of age and older, who were hospitalized during any of the 3 flu seasons from 2011 to 2014 and were admitted and discharged between September 1 and March 31.

Influenza Vaccine Cuts Flu-Related Hospitalization in COPD

Influenza Vaccine Cuts Flu-Related Hospitalization in COPD

Influenza-positive patients have higher rates of crude mortality and critical illness vs influenza-negative patients.

Croup Symptoms, Hospital Readmissions Reduced With Glucocorticoids

Croup Symptoms, Hospital Readmissions Reduced With Glucocorticoids

Children with croup who were given glucocorticoids had reduced symptoms at 2 through 24 hours.

Live Flu Vaccine Less Effective Than Inactivated Vaccine in Children

Live Flu Vaccine Less Effective Than Inactivated Vaccine in Children

Quadrivalent live attenuated influenza vaccine less effective than inactivated vaccine for influenza A/H1N1pdm09.

Influenza Linked to Increased In-Hospital Mortality in Heart Failure

Influenza Linked to Increased In-Hospital Mortality in Heart Failure

In patients with heart failure, influenza infection is associated with increased in-hospital morbidity and mortality.

Child Pneumonia Rate Dropped Globally From 2000 to 2015

Child Pneumonia Rate Dropped Globally From 2000 to 2015

The number of clinical pneumonia episodes in children younger than 5 years of age was reduced by 22% in developing countries.

Severe Rhabdomyolysis in a Patient With Acute Influenza Infection

Severe Rhabdomyolysis in a Patient With Acute Influenza Infection

The patient, who had a history significant for cerebral palsy, seizures, and chronic constipation, had presented complaining of 3 days of fever, nausea, vomiting, and anorexia.

Influenza Seroconversion Risk Factors in Adults Hospitalized for Pneumonia

Influenza Seroconversion Risk Factors in Adults Hospitalized for Pneumonia

Adults hospitalized for pneumonia who received an influenza vaccination during their stay were less likely to seroconvert if they had diabetes, bacterial detection, baseline seropositive titers for influenza B, or influenza vaccination in the previous season.

Increased Risk of Hospitalization for Influenza When Morbidly Obese or Underweight

Increased Risk of Hospitalization for Influenza When Morbidly Obese or Underweight

Adults with influenza were more likely to be hospitalized if they were underweight or morbidly obese compared with normal-weight adults.

Influenza Diagnosis and Treatment Guidelines Updated

Influenza Diagnosis and Treatment Guidelines Updated

Rapid molecular assays should be used to improve influenza diagnosis and antivirals should begin as soon as possible.

NDAs Submitted for Oral, IV Formulations of Lefamulin for CABP

NDAs Submitted for Oral, IV Formulations of Lefamulin for CABP

Nabriva Therapeutics announced the submission of 2 NDAs to the FDA for the oral and IV formulations of lefamulin for the treatment of community-acquired bacterial pneumonia.

Pneumococcal Vaccine May Reduce Resistant Streptococcus Pneumoniae Carriage

Pneumococcal Vaccine May Reduce Resistant Streptococcus Pneumoniae Carriage

A marked and rapid reduction in PCV13 serotype, the most common antibiotic-nonsusceptible S pneumoniae, carriage was observed in both ethnic populations included in this study.

Worse Outcomes From Legionella Pneumonia in Individuals With Advanced HIV

Worse Outcomes From Legionella Pneumonia in Individuals With Advanced HIV

Previous results stated that Legionella pneumonia characteristics may not differ between individuals with HIV and individuals who do not have HIV.

Voriconazole-Resistant Invasive Aspergillosis Associated With Higher Mortality

Voriconazole-Resistant Invasive Aspergillosis Associated With Higher Mortality

Patients with voriconazole-resistant invasive aspergillosis have a higher mortality rate compared with patients with voriconazole-susceptible infection.

Racial Disparities Seen in Teenagers Undergoing Flu Vaccination

Racial Disparities Seen in Teenagers Undergoing Flu Vaccination

Black adolescents have lower odds of receiving influenza vaccination than white adolescents.

Antibody Response to Flu Vaccine Evaluated in Benralizumab-Treated Asthma

Antibody Response to Flu Vaccine Evaluated in Benralizumab-Treated Asthma

The trial analyzed the antibody response of 103 asthmatic patients to the seasonal influenza vaccine.

Mortality With Influenza vs RSV Infection in Older, Hospitalized Adults

Mortality With Influenza vs RSV Infection in Older, Hospitalized Adults

In older, hospitalized adults, respiratory syncytial virus may be associated with greater morbidity and mortality compared with influenza.

Absence of Alveolar Neutrophilia Predictive of Negative Bacterial Pneumonia

Absence of Alveolar Neutrophilia Predictive of Negative Bacterial Pneumonia

Patients undergoing evaluation for ventilator-associated pneumonia who had an alveolar neutrophil percentage 90% for bacterial pneumonia.

Culture Negative Pneumonia Rates Linked to Higher PM2.5 Concentrations

Culture Negative Pneumonia Rates Linked to Higher PM2.5 Concentrations

Increases in the relative rates of culture negative pneumonia that required hospitalization or emergency department visits were significantly associated with increased concentrations of fine particulate air pollution.

Annual Influenza Shots May Lower Risk of CV Death in Heart Failure

Annual Influenza Shots May Lower Risk of CV Death in Heart Failure

A study published in Circulation has found a reduced risk of cardiovascular (CV) death in heart failure patients when they are given routine influenza vaccinations.

Combining Corticosteroids and Antibiotics May Be Cost-Effective in CAP

Combining Corticosteroids and Antibiotics May Be Cost-Effective in CAP

Treating severe community-acquired pneumonia with a combination of corticosteroids and antibiotics may be a cost-effective strategy.

Invasive Pneumococcal Disease Risk Higher in Premature Infants

Invasive Pneumococcal Disease Risk Higher in Premature Infants

Invasive pneumococcal disease was significantly higher in premature infants than in infants born at term.

PCV13 Vaccine Protects Against Serotype 3 Invasive Pneumococcal Disease in Children

PCV13 Vaccine Protects Against Serotype 3 Invasive Pneumococcal Disease in Children

A meta-analysis of case-control studies supports the use of the 13-valent pneumococcal conjugate vaccine in children as it protects against serotype 3.

Hypersensitivity Pneumonitis Prognosis by Phenotype

Hypersensitivity Pneumonitis Prognosis by Phenotype

Compared with idiopathic pulmonary fibrosis, nonhoneycomb hypersensitivity pneumonitis phenotypes are associated with greater improvements in percent-predicted forced vital capacity.

Influenza Vaccine Effectiveness Not Modified by Statin Use

Influenza Vaccine Effectiveness Not Modified by Statin Use

Statin use did not modify the effect of vaccination on influenza in adults ≥45 years.

Lung Transplant Recipients Have New Health-Related Quality of Life Survey

Lung Transplant Recipients Have New Health-Related Quality of Life Survey

The new 60-question Lung Transplant Quality of Life survey measures symptoms, health perceptions, functioning, and well-being.

Influenza Infection Increases Mortality Risk in Acute Myocardial Infarction

Influenza Infection Increases Mortality Risk in Acute Myocardial Infarction

Investigators examined whether influenza is an independent risk factor for the development of acute myocardial infarction.

Bacterial Pneumonia Associated With Increased Risk for Future MACE

Bacterial Pneumonia Associated With Increased Risk for Future MACE

Patients with bacterial pneumonia are at higher risk for major adverse cardiovascular events within 90 days compared with patients with viral pneumonia.

Hands Are Vehicles for Transmission of Streptococcus pneumoniae

Hands Are Vehicles for Transmission of Streptococcus pneumoniae

Hands can be vehicles for transmission of pneumococcus and lead to acquisition of nasopharyngeal colonization.

CHEST Guidelines for Clinical Diagnosis of Pertussis-Associated Cough

CHEST Guidelines for Clinical Diagnosis of Pertussis-Associated Cough

In adult patients, pooled estimates of sensitivity and specificity were generated for 4 clinical features: paroxysmal cough, posttussive vomiting, inspiratory whoop, and absence of fever.

Healthcare-Associated Infections on Decline

Healthcare-Associated Infections on Decline

The risk of having a healthcare-associated infection was 16% lower in 2015 than in 2011.

Radiography Still Common in Pediatric Bronchiolitis Despite AAP Guidelines

Radiography Still Common in Pediatric Bronchiolitis Despite AAP Guidelines

Despite recommendations made by the American Academy of Pediatrics, the use of radiography in pediatric bronchiolitis has not decreased.

Low Levels of Influenza Reported in the United States From May to October

Low Levels of Influenza Reported in the United States From May to October

Seasonal influenza activity was also found to be low in the Southern Hemisphere.

New CHEST Guideline for Acute Cough Due to Suspected Pneumonia or Influenza

New CHEST Guideline for Acute Cough Due to Suspected Pneumonia or Influenza

The CHEST Expert Cough Panel agreed on cough, dyspnea, pleural pain, sweating, shivers, aches, temperature of ≥38°C, tachypnea, and new and localizing chest examination signs as clinical symptoms as criteria suggestive of pneumonia in outpatient adults.

Pneumococcal Vaccine Recs Cause Confusion Among Healthcare Providers

Pneumococcal Vaccine Recs Cause Confusion Among Healthcare Providers

Survey finds variance in provider knowledge of adult pneumococcal vaccine recommendations.

Does Prior Flu Vaccination Affect Subsequent Vaccine Efficacy in Children?

Does Prior Flu Vaccination Affect Subsequent Vaccine Efficacy in Children?

To better understand the influence of prior-season vaccination on subsequent influenza vaccine effectiveness, researchers conducted a multiseason, test-negative case-control study among vaccinated children 2-17 years old recruited during 3 influenza seasons (2013-2014, 2014-2015, and 2015-2016).

Poor Lung Function in Infants From Maternal Exposure to Household Air Pollution

Poor Lung Function in Infants From Maternal Exposure to Household Air Pollution

Significant associations were seen between increased average prenatal carbon monoxide and reduced time to peak tidal expiratory flow to expiratory time, increased respiratory rate, and increased minute ventilation.

Are Asthma Hospitalizations Predictive of Influenza Hospitalizations in NYC Adults?

Are Asthma Hospitalizations Predictive of Influenza Hospitalizations in NYC Adults?

Time-series analysis based on geographic location revealed positive significant associations between asthma and influenza hospitalizations in Brooklyn and Manhattan.

Trivalent, Quadrivalent Inactivated Influenza Vaccine Approved for Patients 6 Months and Older

Trivalent, Quadrivalent Inactivated Influenza Vaccine Approved for Patients 6 Months and Older

The FDA has approved the use of Afluria and Afluria Quadrivalent for use in patients ≥6 months old.

First-in-Class Antiviral Approved for the Treatment of Influenza

First-in-Class Antiviral Approved for the Treatment of Influenza

"This is the first new antiviral flu treatment with a novel mechanism of action approved by the FDA in nearly 20 years," said FDA Commissioner Scott Gottlieb, MD.

Inhaled Corticosteroids Increase Risk for Pulmonary Nontuberculous Mycobacterial Infection

Inhaled Corticosteroids Increase Risk for Pulmonary Nontuberculous Mycobacterial Infection

Patients with pulmonary nontuberculous mycobacterial infections were more likely to have used inhaled corticosteroids than patients with other airway disease.

Giving Flu Shots in Pharmacies Could Increase Vaccination Coverage

Giving Flu Shots in Pharmacies Could Increase Vaccination Coverage

There were reductions in influenza cases, deaths, and costs by adding pharmacies during influenza epidemics.

CDC: Many Pregnant Women Not Receiving Influenza Vaccinations

CDC: Many Pregnant Women Not Receiving Influenza Vaccinations

Fewer than half of women who were pregnant during peak influenza vaccination period in 2017 to 2018 were vaccinated.

Population Density, Structure Impact Length of Flu Season

Population Density, Structure Impact Length of Flu Season

Larger cities with higher base transmission potentials have more diffuse influenza epidemics.

Flu Vaccine Cuts Hospitalization Rates in Pregnant Women

Flu Vaccine Cuts Hospitalization Rates in Pregnant Women

Influenza-related hospitalizations were reduced by 40% over 6 flu seasons.

Strain Selection for Annual Influenza Vaccines Should Consider Preexisting Immunity

Strain Selection for Annual Influenza Vaccines Should Consider Preexisting Immunity

Repeated exposure to the influenza virus affects antibody quantity and quality, and strains selected for seasonal vaccines may not provide coverage sufficient for individuals frequently infected and/or vaccinated.

Antipseudomonal Monotherapy Efficacious in Pneumonia

Antipseudomonal Monotherapy Efficacious in Pneumonia

Antipseudomonal combination therapy has shown poorer efficacy than antipseudomonal monotherapy in individuals with suspected pseudomonal pneumonia.

Statins Increase Risk for Medically Attended Acute Respiratory Illness

Statins Increase Risk for Medically Attended Acute Respiratory Illness

Elderly patients who have been inoculated with the influenza vaccine and who also use a statin are at a greater risk for medically attended acute respiratory illness.

Pneumococcal H Influenzae Protein D Conjugate Vaccine Effective in Children

Pneumococcal H Influenzae Protein D Conjugate Vaccine Effective in Children

The burden of childhood and infant pneumonia can be effectively reduced through the use of the pneumococcal Haemophilus influenzae protein D conjugate vaccine.

PCV13 in Young Adults With Diabetes Could Avert Pneumonia Hospitalizations

PCV13 in Young Adults With Diabetes Could Avert Pneumonia Hospitalizations

PCV13 in adults age <65 years with diabetes could reduce a substantial number of pneumonia hospitalizations.

Novel Intranasal Influenza Vaccine Shows Tolerability, Safety, and High Immune Response

Novel Intranasal Influenza Vaccine Shows Tolerability, Safety, and High Immune Response

NasoVAX, an adenovirus-based intranasal flu vaccine, shows tolerability, safety, and higher cellular immune response compared to an injectable vaccine.

Baloxavir Marboxil Safe and Effective for High-Risk Influenza

Baloxavir Marboxil Safe and Effective for High-Risk Influenza

When compared to placebo, baloxavir marboxil was associated with reduced risk of influenza complications and faster recovery.

Respiratory Tract Infection Telemedicine Visits Shorter When Antibiotics Prescribed

Respiratory Tract Infection Telemedicine Visits Shorter When Antibiotics Prescribed

Findings may highlight physician difficulty explaining to patients why antibiotics are not required.

Antibiotic Stewardship May Aid Stepdown Therapies for Community-Acquired Pneumonia

Antibiotic Stewardship May Aid Stepdown Therapies for Community-Acquired Pneumonia

The use of fluoroquinolones in stable patients with community-acquired pneumonia can be reduced with stewardship programs that share antibiotic use data and provide guidance for step-down therapy.

Omadacycline Approved for Community-Acquired Bacterial Pneumonia

Omadacycline Approved for Community-Acquired Bacterial Pneumonia

The FDA has approved Nuzyra for the treatment of adult patients with CABP and acute bacterial skin and skin structure infections.

Fluoroquinolones May Aid in Reducing Mortality in Community-Acquired Pneumonia

Fluoroquinolones May Aid in Reducing Mortality in Community-Acquired Pneumonia

For patients with CAP, antibiotic regimens including a fluoroquinolone may reduce mortality risk by 1-2% compared to beta-lactams and cephalosporins alone.

Early Oseltamivir Use Linked to Clinical Benefits in Influenza Complicating ARDS

Early Oseltamivir Use Linked to Clinical Benefits in Influenza Complicating ARDS

Patients with acute respiratory distress syndrome and confirmed influenza diagnosis treated ≤6 hours with oseltamivir had reduced length of hospital stay and a lower rate of mortality.

Variations in Influenza Vaccination Coverage Among Healthcare Employees Reported

Variations in Influenza Vaccination Coverage Among Healthcare Employees Reported

Wide variations in influenza vaccine coverage have been noted across healthcare personnel based on occupation and worksite.

Risk Factors for Multidrug-Resistant Pathogens in Pneumonia

Risk Factors for Multidrug-Resistant Pathogens in Pneumonia

Previous antibiotic use and mechanical invasive ventilation were risk factors for multidrug-resistant pathogens in hospital-associated or ventilator-associated pneumonia.

Arikayce Approved to Treat Mycobacterium Avium Complex Lung Disease

Arikayce Approved to Treat Mycobacterium Avium Complex Lung Disease

Arikayce is intended for oral inhalation use and is administered via the Lamira Nebulizer System only.

80,000 Americans Died From Influenza Over Last Year

80,000 Americans Died From Influenza Over Last Year

The 2017 to 2018 flu strains hit the very young and elderly especially hard.

Is Mandatory Genetic Testing for Influenza Infection Variants Ethical?

Is Mandatory Genetic Testing for Influenza Infection Variants Ethical?

Mandatory genetic testing may also constitute an undue threat to employee autonomy and privacy.

Corticosteroids May Prevent Myocardial Infarction in Community-Acquired Pneumonia

Corticosteroids May Prevent Myocardial Infarction in Community-Acquired Pneumonia

Patients with community-acquired pneumonia who received corticosteroids had a lower incidence of myocardial infarction compared with those who did not.

Multivalent Pneumococcal Conjugate Vaccine Gets Breakthrough Tx Designation

Multivalent Pneumococcal Conjugate Vaccine Gets Breakthrough Tx Designation

The Breakthrough designation follows an FDA examination of results from a Phase 2 randomized, double-blind trial which evaluated the safety and immunogenicity of the treatment in adults aged 60 to 64 years.

Active Choice Intervention Tied to Increase in Flu Shot Rates

Active Choice Intervention Tied to Increase in Flu Shot Rates

Vaccination rates decreased throughout the day; with intervention, there was a similar increase throughout day.

Infant PPI Use and Lung Infection Risk: Is There a Link?

Infant PPI Use and Lung Infection Risk: Is There a Link?

The data showed matched odds ratio for current vs past use of PPIs to be 0.88 (95% CI, 0.36 to 2.16) when comparing cases and their controls for community-acquired pneumonia. With regard to lower respiratory tract infections, the matched odds ratio between cases and their controls was 1.13 (95% CI, 0.87 to 1.48).

Factors Predictive of Escalated Care in Infant Bronchiolitis

Factors Predictive of Escalated Care in Infant Bronchiolitis

Factors predictive of escalated care in infant bronchiolitis include oxygen saturation <90%, nasal flaring/grunting, apnea, retractions, and age 2 months or younger.

Positive Results for Zerbaxa in Phase 3 Study of Ventilated HABP, VABP Patients

Positive Results for Zerbaxa in Phase 3 Study of Ventilated HABP, VABP Patients

The full findings from the study will be presented at a future scientific conference; Merck plans to include the data in a supplemental New Drug Application for Zerbaxa which will be submitted to the Food and Drug Administration.

Influenza Caused Emirates Flight to Be Briefly Quarantined at JFK

Influenza Caused Emirates Flight to Be Briefly Quarantined at JFK

New York City health officials say passengers had influenza or other common cold viruses.

Coadjuvant Corticosteroids in Influenza Pneumonia Increases ICU Mortality

Coadjuvant Corticosteroids in Influenza Pneumonia Increases ICU Mortality

Corticosteroids should not be used concomitantly with antiviral therapy in patients with influenza pneumonia.

AAP Issues Updated Influenza Vaccine Recommendations

AAP Issues Updated Influenza Vaccine Recommendations

According to the Centers for Disease Control and Prevention (CDC), the 2017-2018 flu season was one of the most severe - excluding pandemics - on record.

Baloxavir Superior to Placebo for Alleviating Flu Symptoms

Baloxavir Superior to Placebo for Alleviating Flu Symptoms

Baloxavir had a median time to alleviation of symptoms vs placebo, and a similar alleviation time as oseltamivir.

Influenza an Independent Risk Factor for Invasive Pulmonary Aspergillosis

Influenza an Independent Risk Factor for Invasive Pulmonary Aspergillosis

Influenza proved to be an independent risk factor for invasive pulmonary aspergillosis.

CURB-65 Tool in Community-Acquired Pneumonia Useful But Has Limitations

CURB-65 Tool in Community-Acquired Pneumonia Useful But Has Limitations

The clinical prediction tool that uses confusion, uremia, elevated respiratory rate, and hypotension in community-acquired pneumonia demonstrated an association with ICU admittance.

Therapeutic Algorithm May Guide Empiric Therapy in Pneumonia

Therapeutic Algorithm May Guide Empiric Therapy in Pneumonia

An algorithm based on risk factors for resistant pathogens and illness severity can simplify pneumonia treatment, improve the accuracy of empiric therapy, reduce mortality, and help avoid overusing broad spectrum therapy in some patients.

Long-Term PPI Use Linked to Pneumonia Risk in Older Adults

Long-Term PPI Use Linked to Pneumonia Risk in Older Adults

Rate of incident pneumonia increased in second year after initiating treatment with proton pump inhibitors.

Coal Workers' Pneumoconiosis Deaths on the Decline

Coal Workers' Pneumoconiosis Deaths on the Decline

Coal workers' pneumoconiosis deaths significantly decreased from 1999 to 2016 for residents ≥25 years.

Antibiotics Effective in Children With Chronic Wet Cough

Antibiotics Effective in Children With Chronic Wet Cough

Antibiotics were helpful in curing chronic wet cough in children.

CDC: Updated Influenza Vaccination Recommendations for 2018-2019

CDC: Updated Influenza Vaccination Recommendations for 2018-2019

In general, routine annual vaccination is recommended for all patients ≥6 months of age who have no contraindications.

Genome Sequencing Traces K pneumoniae Outbreak to Outpatient Clinic

Genome Sequencing Traces K pneumoniae Outbreak to Outpatient Clinic

An investigation into an outbreak of NDM-producing Klebsiella pneumoniae across 2 Belgian hospitals identified an outpatient clinic as the likely common site of transfer and highlights the importance of infection control measures in outpatient settings.

Treatment for Bronchiolitis Obliterans Gains Orphan Drug Status

Treatment for Bronchiolitis Obliterans Gains Orphan Drug Status

Bronchiolitis obliterans is the leading cause of morbidity and mortality in the pulmonary transplant population with ≥50% of patients who receive a lung transplant developing the condition within 5 years.

Omadacycline Gets FDA Committee Nod for Skin Infections, Pneumonia

Omadacycline Gets FDA Committee Nod for Skin Infections, Pneumonia

The Committee's recommendation was based on data from the omadacycline global development program that included nearly 2000 adults in three Phase 3 studies.

FDA Panel Votes on Therapy for Nontuberculous Mycobacterial Lung Disease

FDA Panel Votes on Therapy for Nontuberculous Mycobacterial Lung Disease

The recommendation was supported by materials developed from the ALIS New Drug Application (NDA), which included data from the CONVERT study.

Flu Vaccine Reduces Mortality in Rheumatoid Arthritis

Flu Vaccine Reduces Mortality in Rheumatoid Arthritis

Hospitalization risk was also reduced for RA patients who received influenza vaccination.

Inappropriate Antibiotic Prescriptions Highest Among Urgent Care Facilities

Inappropriate Antibiotic Prescriptions Highest Among Urgent Care Facilities

Inappropriate antibiotic prescriptions were highest among urgent care facilities (45.7%), with emergency departments (24.6%), medical offices (17.0%), and retail clinics (14.4%) following.

H1N1 Immune Priming and Egg-Adaptation Affect Antibody Responses After Vaccination

H1N1 Immune Priming and Egg-Adaptation Affect Antibody Responses After Vaccination

Immune priming with seasonal H1N1 viruses earlier in life and egg-adaptation in vaccines can impact antibody responses following influenza vaccination.

Drop in Childhood Pneumococcal, Hib Deaths From 2000 to 2015

Drop in Childhood Pneumococcal, Hib Deaths From 2000 to 2015

Most children who died of pneumococcus and Haemophilus influenzae type b presented with pneumonia.

Viral Testing May Reduce Antibiotic Use in Severe Lower Respiratory Infection

Viral Testing May Reduce Antibiotic Use in Severe Lower Respiratory Infection

Advanced diagnostic platforms to identify viruses can help patients with severe lower respiratory tract infections avoid unnecessary diagnostic testing, reduce antibiotic use, and initiate antiviral therapy.

Is Short-Course Antibiotic Treatment for CAP Effective?

Is Short-Course Antibiotic Treatment for CAP Effective?

To investigate what impact antibiotic treatment duration has on CAP outcomes, researchers from the Warren Alpert Medical School of Brown University conducted a search of various databases for studies comparing the safety and efficacy of treatment regimens lasting ≤6 days (short) and ≥7 days (long).

Type 2 Diabetes Does Not Affect Pneumonia Incidence, Outcomes After Stroke

Type 2 Diabetes Does Not Affect Pneumonia Incidence, Outcomes After Stroke

Investigators examined the incidence and outcomes of pneumonia in patients with acute ischemic stroke and type 2 diabetes.

Priority Review Granted to Novel Oral Influenza Treatment

Priority Review Granted to Novel Oral Influenza Treatment

The New Drug Application for baloxavir marboxil is supported by results from the Phase 3 CAPSTONE-1 study (N=1436) which examined the effects of a single dose of baloxavir marboxil vs placebo or oseltamivir 75mg twice daily for 5 days.

Community-Acquired Pneumonia In-Hospital Deaths Are Not Indicative of Lapse in Care

Community-Acquired Pneumonia In-Hospital Deaths Are Not Indicative of Lapse in Care

Most deaths related to community-acquired pneumonia that occurred at tertiary-case hospitals were not preventable.

Respiratory Viruses Linked to Treatment Failure in Asthma Exacerbations

Respiratory Viruses Linked to Treatment Failure in Asthma Exacerbations

Respiratory pathogens were associated with an increased risk for treatment failure in children with asthma exacerbations.

Misuse of Antibiotics Common in Outpatient Acute Respiratory Infections

Misuse of Antibiotics Common in Outpatient Acute Respiratory Infections

The researchers argued that outpatient antibiotic stewardship efforts must be strengthened to eliminate antibiotic treatment for viral upper respiratory infections and acute bronchitis.

PCV13 Reduces Hospitalization for Vaccine-Type Community-Acquired Pneumonia

PCV13 Reduces Hospitalization for Vaccine-Type Community-Acquired Pneumonia

The real-world effectiveness of PCV13 vaccine in preventing hospitalization for vaccine-type community-acquired pneumonia was assessed.

C-Reactive Protein as a Biomarker for CAP in Bronchiectasis

C-Reactive Protein as a Biomarker for CAP in Bronchiectasis

Although clinical presentation was similar in both community-acquired pneumonia and non-pneumonia exacerbations, CRP, glucose, and leukocytes were higher in the former vs the latter.

Early Clinical Response With Omadacycline vs Moxifloxacin in CABP

Early Clinical Response With Omadacycline vs Moxifloxacin in CABP

Early clinical response rates were similar across PORT risk class subgroups in patients with community-acquired bacterial pneumonia when treated with omadacycline or moxifloxacin.

Prevnar 13 Linked to Reduced Risk of CAP Hospitalization in Older Patients

Prevnar 13 Linked to Reduced Risk of CAP Hospitalization in Older Patients

PCV13, marketed as Prevnar 13, was evaluated in a test-negative case-control study in real-world conditions where patients were administered pneumococcal vaccination as advised by their healthcare providers.

AAP Recommends Shot Over Nasal Spray for 2018-2019 Flu Season

AAP Recommends Shot Over Nasal Spray for 2018-2019 Flu Season

The advisory comes early as physicians are currently placing vaccine orders.

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