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PCV13 Reduces Hospitalization for Vaccine-Type Community-Acquired Pneumonia

PCV13 Reduces Hospitalization for Vaccine-Type Community-Acquired Pneumonia

The real-world effectiveness of PCV13 vaccine in preventing hospitalization for vaccine-type community-acquired pneumonia was assessed.

C-Reactive Protein as a Biomarker for CAP in Bronchiectasis

C-Reactive Protein as a Biomarker for CAP in Bronchiectasis

Although clinical presentation was similar in both community-acquired pneumonia and non-pneumonia exacerbations, CRP, glucose, and leukocytes were higher in the former vs the latter.

Early Clinical Response With Omadacycline vs Moxifloxacin in CABP

Early Clinical Response With Omadacycline vs Moxifloxacin in CABP

Early clinical response rates were similar across PORT risk class subgroups in patients with community-acquired bacterial pneumonia when treated with omadacycline or moxifloxacin.

Prevnar 13 Linked to Reduced Risk of CAP Hospitalization in Older Patients

Prevnar 13 Linked to Reduced Risk of CAP Hospitalization in Older Patients

PCV13, marketed as Prevnar 13, was evaluated in a test-negative case-control study in real-world conditions where patients were administered pneumococcal vaccination as advised by their healthcare providers.

AAP Recommends Shot Over Nasal Spray for 2018-2019 Flu Season

AAP Recommends Shot Over Nasal Spray for 2018-2019 Flu Season

The advisory comes early as physicians are currently placing vaccine orders.

Positive Results Announced for Pleuromutilin Antibiotic in CABP

Positive Results Announced for Pleuromutilin Antibiotic in CABP

In the LEAP 2 study (N=738), patients with moderate CABP received either oral lefamulin 600mg every 12 hours for 5 days or oral moxifloxacin 400mg once daily for 7 days.

Prior Atypical Antipsychotic Use May Increase Mortality Risk in Pneumonia

Prior Atypical Antipsychotic Use May Increase Mortality Risk in Pneumonia

Clinicians should consider these findings when using atypical antipsychotics in patients at risk for pneumonia.

Hypersensitivity Pneumonitis Prevalence in an Insured US Population

Hypersensitivity Pneumonitis Prevalence in an Insured US Population

Researchers have developed a novel algorithm to identify hypersensitivity pneumonitis.

Pediatric Pneumonia: Sensitivity of Lung Ultrasound vs Chest Radiography

Pediatric Pneumonia: Sensitivity of Lung Ultrasound vs Chest Radiography

Lung ultrasound was more effective in diagnosing pediatric community-acquired pneumonia than chest radiography.

Legionella Pneumonia Outcomes Similar in Adults With/Without HIV

Legionella Pneumonia Outcomes Similar in Adults With/Without HIV

Clinical presentation and outcomes in HIV-infected patients with Legionella pneumonia did not differ from patients without HIV infection.

Low-Dose CT May Modify Pneumonia Diagnosis in Elderly Patients

Low-Dose CT May Modify Pneumonia Diagnosis in Elderly Patients

Low-dose computed tomography may assist clinicians in modifying diagnosis of elderly patients who are admitted with suspected pneumonia.

Flu Vaccines Have High Impact, Even With Relatively Low Efficacy

Flu Vaccines Have High Impact, Even With Relatively Low Efficacy

A high impact was seen, especially when the vaccine uptake was optimally distributed across age groups.

Pneumonia Risk in Severe COPD Linked to Elevated Eosinophil Count

Pneumonia Risk in Severe COPD Linked to Elevated Eosinophil Count

A higher proportion of patients with COPD and a blood eosinophil count of ≥0.34×109/L had elevated markers of low-grade systemic inflammation regardless of forced expiratory volume in 1 second.

ACOG: Updated Recommendations for Influenza Vaccination During Pregnancy

ACOG: Updated Recommendations for Influenza Vaccination During Pregnancy

This updated Committee Opinion includes more recent data on the safety and efficacy of influenza vaccination during pregnancy, as well as recommendations for treatment and postexposure chemoprophylaxis.

Adult Caregivers Likely to Receive Influenza Vaccination From Pediatric Clinics

Adult Caregivers Likely to Receive Influenza Vaccination From Pediatric Clinics

Adult caretaker influenza vaccination cocooning programs can prove beneficial and financially successful in private practice models where external funding is limited or not available.

Paracetamol Overuse During Cold and Flu Season

Paracetamol Overuse During Cold and Flu Season

During the cold and flu season, the use and over-dosing of paracetamol is common, and may partially be driven by higher use of over-the-counter combination medications for the treatment of upper respiratory cold/flu symptoms.

Increased Risk for Acute Respiratory Illness Following Influenza Vaccine in Children

Increased Risk for Acute Respiratory Illness Following Influenza Vaccine in Children

Among children there was an increased risk for acute respiratory illness caused by noninfluenza respiratory pathogens following influenza vaccination compared to unvaccinated children during the same period.

Mortality in Mechanically Ventilated Community-Acquired Pneumonia With or Without ARDS

Mortality in Mechanically Ventilated Community-Acquired Pneumonia With or Without ARDS

The risk for death in patients with community-acquired pneumonia who were given mechanical ventilation does not seem to be affected by the presence of acute respiratory distress syndrome.

Pneumonia and Influenza May Trigger Acute MI, Stroke

Pneumonia and Influenza May Trigger Acute MI, Stroke

Researchers found increased myocardial infarction rates during the week after Streptococcus pneumoniae and influenza infections.

Respiratory Syncytial Virus Prevention and Asthma in Preterm Infants

Respiratory Syncytial Virus Prevention and Asthma in Preterm Infants

Researchers assessed the relationship between prevention of RSV in preterm infants and the frequency of subsequent wheeze in childhood.

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