DASS-21 Demonstrates Validity, Responsiveness in COPD

DASS-21 Demonstrates Validity, Responsiveness in COPD

The Depression, Anxiety, and Stress Scale (DASS-21) demonstrated validity in individuals with COPD underwent an 8-week pulmonary rehabilitation program.

Importance of Contingency Plans in Asthma Clinical Trials

Importance of Contingency Plans in Asthma Clinical Trials

When designing either biomarker-stratified or phenotype-directed protocols for asthma-related clinical trials, including a contingency plan can help manage scenarios in which phenotypes in the study sample differ in prevalence from expected values.

Good Sleep Hygiene in Adolescents With Asthma Linked to Improved Attention

Good Sleep Hygiene in Adolescents With Asthma Linked to Improved Attention

Adolescents with asthma who practice good sleep hygiene may experience improvements in sleep and attention span, better quality of life in school, and lower rates of dysfunction during the daytime.

Primary Ciliary Dyskinesia: Practical Pearls for Diagnosis

Primary Ciliary Dyskinesia: Practical Pearls for Diagnosis

Recent guidelines set forth by an interdisciplinary panel assembled by the American Thoracic Society sought to demystify primary ciliary dyskinesia and address 4 main diagnostic questions.

Home-Based Environmental Control Intervention Not Effective in Pediatric Asthma

Home-Based Environmental Control Intervention Not Effective in Pediatric Asthma

Children with poorly controlled asthma who underwent a home-based environmental control intervention had the same risk for repeat emergency department visits as children who did not receive the intervention.

Early Intervention in Pediatric Asthma: What Are the Long-Term Effects?

Early Intervention in Pediatric Asthma: What Are the Long-Term Effects?

Although uncontrolled asthma in early childhood can have enduring effects on lung development, whether the use of traditional interventions in very young pediatric patients can actually preserve pulmonary function is unclear.

Weight Loss Interventions in Asthma May Improve Patient Outcomes

Weight Loss Interventions in Asthma May Improve Patient Outcomes

All of the randomized controlled trials evaluated had successful improvements in weight or body mass index in patients with asthma.

Asthma Linked to Fertility Treatments and Miscarriages in New Study

Asthma Linked to Fertility Treatments and Miscarriages in New Study

A new study found that subfertility and the use of assisted reproductive technologies may increase the risk for asthma in offspring.

Asthma Undiagnosed in 1 in 5 Urban Adolescents

Asthma Undiagnosed in 1 in 5 Urban Adolescents

Odds of being undiagnosed with asthma are higher for girls, and Asian-Americans vs white non-Hispanics.

Asthma Control and Medication Adherence: Time for a Digital Intervention

Asthma Control and Medication Adherence: Time for a Digital Intervention

Digital interventions, such as web-based programs, mobile apps, and text messaging, have been found to improve asthma control and medication adherence while reducing the use of "rescue" medications.

COPD Exacerbations May Be Reduced With Vitamin D

COPD Exacerbations May Be Reduced With Vitamin D

The review showed supplementation was only effective for baseline vitamin D levels <25 nmol/L.

Cardiovascular Comorbidity Screening Should Be Conducted in COPD With Obesity

Cardiovascular Comorbidity Screening Should Be Conducted in COPD With Obesity

Hypertension and diabetes are especially prevalent comorbidities in obese patients with chronic obstructive pulmonary disease.

Pediatric Asthma Risk Score Outperforms Asthma Predictive Index

Pediatric Asthma Risk Score Outperforms Asthma Predictive Index

A new quantitative personalized tool to predict asthma development in young children predicted asthma development reliably.

Asthma Symptoms Exacerbated From E-Cigarette Aerosol Exposure

Asthma Symptoms Exacerbated From E-Cigarette Aerosol Exposure

Findings were seen in youth reporting asthma diagnosis and secondhand exposure to e-cigarette aerosols.

Depression Tied to Worse Asthma Outcomes in Urban Teenagers

Depression Tied to Worse Asthma Outcomes in Urban Teenagers

More than a fourth of teenagers with asthma reported depressive symptoms and greater symptom severity.

Influenza Vaccine Cuts Flu-Related Hospitalization in COPD

Influenza Vaccine Cuts Flu-Related Hospitalization in COPD

Influenza-positive patients have higher rates of crude mortality and critical illness vs influenza-negative patients.

Smoking Habits Do Not Differ in Teens With, Without Asthma

Smoking Habits Do Not Differ in Teens With, Without Asthma

Researchers examined self-reported smoking habits at age 16 years among adolescents and parents in relation to phenotypes of asthma.

Children With Asthma Prescribed More Antibiotics Than Those Without

Children With Asthma Prescribed More Antibiotics Than Those Without

Children with asthma are prescribed antibiotics at a higher rate than children without asthma.

Hypercapnic COPD Survival, Clinical Outcomes With High-Intensity NIV

Hypercapnic COPD Survival, Clinical Outcomes With High-Intensity NIV

Patients with comorbid stable COPD and chronic hypercapnic respiratory failure have improved symptoms and survival rates with high-intensity noninvasive ventilation.

Physician-Diagnosed Asthma Criteria Inconsistent With Official Guidelines

Physician-Diagnosed Asthma Criteria Inconsistent With Official Guidelines

Pediatric pulmonologists most often chose symptom resolution following treatment with bronchodilators as the key clinical criterion for asthma diagnosis.

Keeping Up-to-Date on COPD Controversies: A Clinician Interview

Keeping Up-to-Date on COPD Controversies: A Clinician Interview

The GOLD scientific committee published a report on current controversies in COPD, including the role of cigarette smoking vs biomass exposure, the role of thoracic imaging, and different treatment strategies.

First Digital Inhaler With Built-In Sensors Gets FDA Approval

First Digital Inhaler With Built-In Sensors Gets FDA Approval

ProAir Digihaler is the first digital inhaler with built-in sensors that connects to a mobile application and provides data on inhaler use to patients with asthma and chronic obstructive pulmonary disease (COPD).

Overlap Syndrome in COPD and OSA Is Up 4-Fold in Medicare Beneficiaries

Overlap Syndrome in COPD and OSA Is Up 4-Fold in Medicare Beneficiaries

The prevalence of overlap syndrome in obstructive sleep apnea and COPD in Medicare beneficiaries increased 4-fold from 2004 to 2013.

COPD Assessment Test May Help Determine Severity of Bronchiectasis

COPD Assessment Test May Help Determine Severity of Bronchiectasis

The COPD assessment test proved to be valid and reproducible in assessing the impact effect and severity of bronchiectasis symptoms in patients with COPD.

Six-Second Exhalation Appropriate for Nitric Oxide Evaluation in Pediatric Asthma

Six-Second Exhalation Appropriate for Nitric Oxide Evaluation in Pediatric Asthma

Children with asthma who had their fractional exhaled nitric oxide measured using a 6-second exhalation had consistent results that agreed with 10-second exhalation measurements.

Oral Corticosteroid-Sparing Effects: Tralokinumab in Severe Asthma

Oral Corticosteroid-Sparing Effects: Tralokinumab in Severe Asthma

The use of tralokinumab was not associated with oral corticosteroid-sparing effects in patients with severe asthma.

COPD and Obesity: Is There a Dose-Response Relationship in Nonsmokers?

COPD and Obesity: Is There a Dose-Response Relationship in Nonsmokers?

The odds of developing COPD were considerably higher in both men and women with class III obesity compared with normal weight individuals.

Bronchiectasis Severity Associated With Pulmonary Vascular Pruning

Bronchiectasis Severity Associated With Pulmonary Vascular Pruning

Mild bronchiectasis in smokers is associated with distal pulmonary vascular pruning.

Hypertonic Saline Inhalation Safety Tested in Infants With Cystic Fibrosis

Hypertonic Saline Inhalation Safety Tested in Infants With Cystic Fibrosis

In infants with cystic fibrosis, preventive inhalation with hypertonic saline during the first months of life is safe and well tolerated and results in clinical improvements, according to a new study.

Anxiety in COPD Benefits From Cognitive Behavioral Therapy vs Self-Help

Anxiety in COPD Benefits From Cognitive Behavioral Therapy vs Self-Help

Cognitive behavioral therapy interventions were statistically and clinically superior to self-help leaflets in the treatment of anxiety in patients with COPD.

Oral Corticosteroid Use in Asthma May Increase Risk for Complications

Oral Corticosteroid Use in Asthma May Increase Risk for Complications

The study authors aimed to assess AE risk and complications of OCS use in patients with asthma since most studies only report them in non-asthmatic patients.

Antibody Response to Flu Vaccine Evaluated in Benralizumab-Treated Asthma

Antibody Response to Flu Vaccine Evaluated in Benralizumab-Treated Asthma

The trial analyzed the antibody response of 103 asthmatic patients to the seasonal influenza vaccine.

Frailty Linked to Poor Health Outcomes in COPD

Frailty Linked to Poor Health Outcomes in COPD

Patients with COPD who were considered frail were more likely to have lower quality of life, increased rate and length of hospitalization, and a higher rate of mortality.

PM2.5 Exposure Linked to Asthma Rescue Medication Use

PM2.5 Exposure Linked to Asthma Rescue Medication Use

A 12% decrease in PM2.5 concentrations would result in an economic benefit of nearly $350 million annually.

Lower Maternal Vitamin D and E Intake Linked to Higher Childhood Asthma Risk

Lower Maternal Vitamin D and E Intake Linked to Higher Childhood Asthma Risk

The risk for asthma and wheezing in the first 10 years of childhood have been linked to a low maternal intake of vitamins D and E.

Self-Management Support Improves Quality of Life in COPD

Self-Management Support Improves Quality of Life in COPD

Compared with usual care, a comprehensive 3-month program combining transition and long-term self-management support for patients with COPD led to significantly fewer COPD-related hospitalizations and greater quality of life.

Omalizumab Shows Promise as Rescue Therapy in Status Asthmaticus

Omalizumab Shows Promise as Rescue Therapy in Status Asthmaticus

Omalizumab rescue therapy produced rapid results in a patient with refractory status asthmaticus.

COPD Tied to Obesity in Never-Smokers

COPD Tied to Obesity in Never-Smokers

A strong dose-response relationship was seen in never-smokers aged 50 and older.

Multiple Breath Washout Test Inaccuracies Revealed Via Over-Reader Assessment

Multiple Breath Washout Test Inaccuracies Revealed Via Over-Reader Assessment

Including invalid data decreases the validity of multiple breath washout measurements in clinical trials involving adults with bronchiectasis.

COPD Short-Term Outcomes Predicted by Risk Scale

COPD Short-Term Outcomes Predicted by Risk Scale

Ottawa COPD Risk Scale is valid for predicting short-term serious outcomes for patients in the emergency department.

Blood Eosinophilia-Targeted COPD Treatment: LABA-ICS vs LAMAs

Blood Eosinophilia-Targeted COPD Treatment: LABA-ICS vs LAMAs

Blood eosinophil concentrations could be used to target patients with chronic obstructive pulmonary disease who are likely to respond to initial long-acting bronchodilator therapy.

COPD Prevalence Higher in Poor and Rural Communities

COPD Prevalence Higher in Poor and Rural Communities

Living in a rural community was a predictor for COPD prevalence, whether the individual had a history of smoking or was a current smoker.

COPD May Predict Mortality in Ventricular Tachyarrhythmias, Sudden Cardiac Arrest

COPD May Predict Mortality in Ventricular Tachyarrhythmias, Sudden Cardiac Arrest

The presence of COPD is linked to higher all-cause mortality and cardiac death at 24 hours in high-risk patients who present with ventricular tachyarrhythmias and sudden cardiac arrest.

Fatty Fish and Mediterranean Diet Effective as Asthma Treatment in Children

Fatty Fish and Mediterranean Diet Effective as Asthma Treatment in Children

A Mediterranean diet, including 2 servings of fatty fish per week, has the potential to reduce airway inflammation in children with asthma.

Sputum Microbiome May Predict Prognosis After COPD Hospitalization

Sputum Microbiome May Predict Prognosis After COPD Hospitalization

Decreasing alpha diversity in the microbiome profile of sputum samples of patients hospitalized with COPD acute exacerbations was associated with increased 1-year mortality.

Mepolizumab Considered Safe, Effective for Severe Eosinophilic Asthma

Mepolizumab Considered Safe, Effective for Severe Eosinophilic Asthma

Mepolizumab demonstrated long-term safety and efficacy in the management of severe eosinophilic asthma.

COPD, Nocturnal Hypoxemia May Increase CV Events in Women With Suspected OSA

COPD, Nocturnal Hypoxemia May Increase CV Events in Women With Suspected OSA

Nocturnal hypoxemia, along with COPD, increased the risk for cardiovascular events and mortality in female patients with suspected obstructive sleep apnea.

Traveling by Airplane With COPD: Expert Advice

Traveling by Airplane With COPD: Expert Advice

Healthcare providers should educate all patients with COPD about their flight-related risks and the need to seek medical advice before flying.

Telling Time by Asthma, Allergy Symptom Severity

Telling Time by Asthma, Allergy Symptom Severity

Clinicians are gaining a better understanding of how asthma and allergies are regulated by the circadian clock, which will help patients better alleviate their symptoms.

VX-445-Tezacaftor-Ivacaftor May Improve CFTR in Cystic Fibrosis

VX-445-Tezacaftor-Ivacaftor May Improve CFTR in Cystic Fibrosis

VX-445-tezacaftor-ivacaftor led to noticeable improvements in Phe508del CFTR protein function.

Endobronchial Valve Therapy: A Nonsurgical Option for Advanced Emphysema

Endobronchial Valve Therapy: A Nonsurgical Option for Advanced Emphysema

Bronchoscopic lung volume reduction with valve replacement shows the most promise for improving lung function, exercise tolerance, and quality of life in patients with advanced emphysema.

Overweight, Obesity in Childhood Linked to Increased Asthma Risk

Overweight, Obesity in Childhood Linked to Increased Asthma Risk

In the absence of overweight and obesity, 10% of all pediatric asthma cases would be avoided.

Childhood Asthma, Wheezing Linked to Maternal Blood Pressure in Pregnancy

Childhood Asthma, Wheezing Linked to Maternal Blood Pressure in Pregnancy

Consistent associations were observed per 5 mm Hg higher maternal blood pressures in early pregnancy with lower FEV1/FVC.

Insurance Gaps May Increase Emergency Department Visits in Children With Asthma

Insurance Gaps May Increase Emergency Department Visits in Children With Asthma

Gaps in insurance coverage increased the odds of asthma-related emergency department intervention or hospitalization and exacerbations.

Symptom Free Days Questionnaire Lacks Reliability in Black Asthma Patients

Symptom Free Days Questionnaire Lacks Reliability in Black Asthma Patients

The Symptom Free Days Questionnaire may not be a reliable measurement in black patients with asthma.

Pediatric Asthma Hospital Stay and Caregiver Knowledge Linked

Pediatric Asthma Hospital Stay and Caregiver Knowledge Linked

Children of caregivers with poor asthma knowledge more likely to have prolonged hospital stay

Which Drug Combination Works Best to Reduce Acute COPD Exacerbations?

Which Drug Combination Works Best to Reduce Acute COPD Exacerbations?

Compared with a combination treatment of LABA/LAMA, ICS/LABA/LAMA combination therapy was associated with a significantly greater pooled risk reduction in COPD exacerbation.

Maximum Symptom Day Validated as Measure of Asthma Control

Maximum Symptom Day Validated as Measure of Asthma Control

The maximum symptom day has been confirmed as a reliable, responsive, and valid tool for measuring asthma symptom control.

Patients Hospitalized for COPD Rarely Receive Pulmonary Rehab

Patients Hospitalized for COPD Rarely Receive Pulmonary Rehab

Few individuals hospitalized for COPD receive pulmonary rehabilitation.

Increased Medication Burden for Patients With Both Asthma and Allergies

Increased Medication Burden for Patients With Both Asthma and Allergies

Patients with both asthma and allergies had a significant increase in the number of prescriptions dispensed for controller medications.

Reslizumab Improves Sleep Quality in Inadequately Controlled Asthma

Reslizumab Improves Sleep Quality in Inadequately Controlled Asthma

Patients who received reslizumab experienced significantly greater improvements in each sleep-related related Asthma Quality of Life Questionnaire question score compared with placebo.

Lung Function in Persistent Asthma Improves With Inhaled Beclomethasone Dipropionate

Lung Function in Persistent Asthma Improves With Inhaled Beclomethasone Dipropionate

Significant improvements were seen in lung function in patients who received either dose of beclomethasone dipropionate.

Asthma Treatment Adherence: Once-Daily vs Twice-Daily Regimens

Asthma Treatment Adherence: Once-Daily vs Twice-Daily Regimens

The mean proportion of days covered in the fluticasone furoate/vilanterol group was significantly higher than in the budesonide/formoterol and fluticasone propionate/salmeterol groups.

Benralizumab Reduces Rescue Medication Use in Severe Eosinophilic Asthma

Benralizumab Reduces Rescue Medication Use in Severe Eosinophilic Asthma

By day 3, patients with severe eosinophilic asthma who received benralizumab required less use of rescue medication.

Lung Function in Asthma Improves With Add-On Tiotropium

Lung Function in Asthma Improves With Add-On Tiotropium

Add-on tiotropium therapy improved lung function compared with placebo in moderate asthma.

Shared Decision Making in Asthma Improves With Use of Facilitator-Led Education

Shared Decision Making in Asthma Improves With Use of Facilitator-Led Education

Facilitator-led sites had a higher percentage of patients who reported equal participation with their provider in making asthma treatment decisions vs the lunch-and-learn sites.

Dupilumab Improves Asthma Control Regardless of Exacerbation History

Dupilumab Improves Asthma Control Regardless of Exacerbation History

Better asthma control, as indicated by lower mean scores on the Asthma Control Questionnaire-5, were seen in both the dupilumab and placebo groups.

3D Super Clusters in COPD Could Affect Adjacent Healthy Tissue

3D Super Clusters in COPD Could Affect Adjacent Healthy Tissue

Three-dimensional "super clusters" in patients with COPD could play a role in the progression of COPD to emphysema.

Several Asthma, Allergy Groups Express "Deep Concern" Over Primatene MIST Approval

Several Asthma, Allergy Groups Express "Deep Concern" Over Primatene MIST Approval

Several asthma and allergy groups expressed "deep concern" over the recent FDA approval of Primatene MIST.

Elevated Tuberculosis Risk in Inhaled Corticosteroid Users

Elevated Tuberculosis Risk in Inhaled Corticosteroid Users

There may an increased risk for tuberculosis in patients with COPD within 3 years of inhaled corticosteroid use.

Once-Daily, Nebulized Bronchodilator Approved for COPD Treatment

Once-Daily, Nebulized Bronchodilator Approved for COPD Treatment

The FDA has approved Yupelri inhalation solution for the maintenance treatment of patients with COPD.

Cystic Fibrosis Lung Function Improved With Triple Therapy

Cystic Fibrosis Lung Function Improved With Triple Therapy

Adding VX-659 to tezacaftor and ivacaftor therapy improved lung function in patients with cystic fibrosis.

Epinephrine Inhalation Aerosol Returning to Market as OTC Asthma Inhaler

Epinephrine Inhalation Aerosol Returning to Market as OTC Asthma Inhaler

The new inhalation delivery system no longer includes CFC. It contains hydrofluroalkane (HFA) propellants and also features a built-in spray indicator and metal canister, replacing the glass container seen with the original Primatene Mist.

Obesity Linked to Respiratory Infection Risk in Asthma

Obesity Linked to Respiratory Infection Risk in Asthma

Higher BMI in adults was related to an increase in moderate to severe upper respiratory infections.

Self-Reporting Tool May Be Valid for Asthma Control Assessment in Adolescents

Self-Reporting Tool May Be Valid for Asthma Control Assessment in Adolescents

The ACCI includes questions about changes in asthma status, perceptions of disease burden, emergency room visits and hospitalizations, steroid use, adherence to prescribed medications, and symptom frequency.

Paradoxical Bronchospasm With SABA Therapy: An Underrecognized Adverse Effect

Paradoxical Bronchospasm With SABA Therapy: An Underrecognized Adverse Effect

Paradoxical bronchoconstriction is an underrecognized adverse event that can occur with administration of β2-agonist-containing inhaler formulations.

Asthma-COPD Overlap Prevalence, Severity in Low- and Middle-Income Countries

Asthma-COPD Overlap Prevalence, Severity in Low- and Middle-Income Countries

The overall rate of asthma-COPD overlap was 3.8%, with a maximum prevalence of 7.8% in Matlab, Bangladesh.

Theophylline Adjunct Therapy Fails to Reduce COPD Exacerbations

Theophylline Adjunct Therapy Fails to Reduce COPD Exacerbations

Adults with COPD treated with both inhaled corticosteroids and low-dose theophylline as adjunct therapy did not have fewer exacerbations compared with patients treated with inhaled corticosteroids only.

Chest Radiographs Infrequently Yield Positive Findings in Children With Asthma and Chest Pain

Chest Radiographs Infrequently Yield Positive Findings in Children With Asthma and Chest Pain

The use of chest radiographs in children with asthma who complain of chest pain should be limited, according to a new study.

Half of COPD Inhaler Use Does Not Align With GOLD Recommendations

Half of COPD Inhaler Use Does Not Align With GOLD Recommendations

Half of patients with COPD report use of inhaler medications that are not in alignment with the current treatment recommendations.

Oxygen-Driven vs Air-Driven Nebulizers for COPD Exacerbations

Oxygen-Driven vs Air-Driven Nebulizers for COPD Exacerbations

Air-driven bronchodilator nebulization is preferable to oxygen-driven nebulization in patients experiencing acute COPD exacerbations.

COPD May Predict Complications in Percutaneous Coronary Interventions

COPD May Predict Complications in Percutaneous Coronary Interventions

The increased occurrence of periprocedural complications in patients with COPD was largely attributed to cardiac arrest, myocardial infarctions, and no-reflows.

Childhood Asthma Risk May Increase With Prenatal Animal Exposure

Childhood Asthma Risk May Increase With Prenatal Animal Exposure

Children exposed to cats, dogs, goats, cockroaches, and rats while in utero were more likely to develop asthma.

Albuminuria Associated With Lung Function Decline in COPD

Albuminuria Associated With Lung Function Decline in COPD

Albuminuria was associated with greater lung function decline in patients with chronic obstructive pulmonary disease.

Are Asthma Hospitalizations Predictive of Influenza Hospitalizations in NYC Adults?

Are Asthma Hospitalizations Predictive of Influenza Hospitalizations in NYC Adults?

Time-series analysis based on geographic location revealed positive significant associations between asthma and influenza hospitalizations in Brooklyn and Manhattan.

Rhinitis Nearly Ubiquitous in Urban Adolescents With Asthma

Rhinitis Nearly Ubiquitous in Urban Adolescents With Asthma

The majority of study participants had rhinitis at baseline, including perennial allergic rhinitis with seasonal exacerbations, which is the most severe phenotype.

Metered Dose Inhalers in Asthma Lower Hospitalization Rates

Metered Dose Inhalers in Asthma Lower Hospitalization Rates

Changing to bronchodilator treatment with a metered dose inhaler in patients with mild to moderate asthma resulted in lower hospitalization rates, shorter hospital stays, and a decrease in continuous use of albuterol.

Dupilumab Approved as Add-On Maintenance Tx for Moderate-to-Severe Asthma

Dupilumab Approved as Add-On Maintenance Tx for Moderate-to-Severe Asthma

The FDA has approved Dupixent as an add-on maintenance treatment in patients with moderate-to-severe asthma aged 12 years and older with an eosinophilic phenotype or with oral corticosteroid-dependent asthma.

CFTR Dysfunction Likely Associated With Worsened Airway Disease in Smokers

CFTR Dysfunction Likely Associated With Worsened Airway Disease in Smokers

Cystic fibrosis transmembrane conductance regulator dysfunction is associated with worsened airway disease in patients with COPD.

Asthma Risk in Infants Predicted by Total Serum Bilirubin

Asthma Risk in Infants Predicted by Total Serum Bilirubin

Total serum bilirubin levels of 9 to 11.9 mg/dL, 12 to 14.9 mg/dL, and 15 to 17.9 mg/dL were associated with significantly greater risks for asthma in infants.

Childhood Non-Atopic Rhinitis Increases Adult Asthma Risk

Childhood Non-Atopic Rhinitis Increases Adult Asthma Risk

Childhood non-atopic rhinitis is associated with an increased risk for adult asthma.

COPD Mortality Does Not Increase From Long-Term Use of Benzodiazepines

COPD Mortality Does Not Increase From Long-Term Use of Benzodiazepines

No difference in mortality, but there may be an elevated risk for suicide with long-term benzodiazepine use in patients with COPD and comorbid PTSD.

Effects of Testosterone Replacement Therapy in Men With COPD

Effects of Testosterone Replacement Therapy in Men With COPD

Middle-aged testosterone replacement therapy users with COPD had a greater reduction in hospitalizations compared with nonusers.

Novel Inhaled Treatment for Cystic Fibrosis Granted Orphan Drug Designation

Novel Inhaled Treatment for Cystic Fibrosis Granted Orphan Drug Designation

The FDA has granted Orphan Drug Designation to a novel inhaled treatment that could potentially improve lung function in patients with cystic fibrosis.

Smoking of Any Amount Is Proportionally Linked With Lung Disease

Smoking of Any Amount Is Proportionally Linked With Lung Disease

The risk for obstructive lung disease was nearly 8 times greater in heavy stable smokers compared with never-smokers.

Early-Onset Asthma/Wheezing Associated With Later Childhood Obesity

Early-Onset Asthma/Wheezing Associated With Later Childhood Obesity

Children with asthma had a 66% higher risk for incident obesity compared with children without asthma.

Gas Trapping Improved With Bronchial Thermoplasty in Severe Asthma

Gas Trapping Improved With Bronchial Thermoplasty in Severe Asthma

Bronchial thermoplasty reduced gas trapping in individuals with asthma, particularly in patients with severe disease.

Early Pulmonary Rehabilitation Lowers Mortality After COPD Exacerbation

Early Pulmonary Rehabilitation Lowers Mortality After COPD Exacerbation

Early pulmonary rehabilitation after hospitalization for an acute exacerbation of COPD was an effective intervention for reducing mortality.

Tiotropium Bromide and Olodaterol Labeling Updated With Revised Indication

Tiotropium Bromide and Olodaterol Labeling Updated With Revised Indication

The FDA has approved updated labeling for Stiolto Respimat to include COPD exacerbation data and a revised indication.

Hospital Readmissions Reduced for COPD With Discharge Care Bundle

Hospital Readmissions Reduced for COPD With Discharge Care Bundle

Patients who received a discharge care bundle after being hospitalized for an acute exacerbation of COPD had a lower rate of readmission.

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