Hailie Sensor Gets FDA Clearance for Additional Asthma Inhalers

Hailie Sensor Gets FDA Clearance for Additional Asthma Inhalers

The Hailie sensor attaches to the asthma or chronic obstructive pulmonary disease (COPD) inhaler to monitor and help patient adherence.

Asthma Hospitalization Risk in Children From Grass, Weed, and Other Pollens

Asthma Hospitalization Risk in Children From Grass, Weed, and Other Pollens

Grass, other weeds, and unclassified pollen were significantly associated with increased risk for asthma hospitalization in young children.

Illicit Drug Use in Asthma: Heroin, Cocaine, and Marijuana Worsen Symptoms

Illicit Drug Use in Asthma: Heroin, Cocaine, and Marijuana Worsen Symptoms

Inhaling and smoking heroin and cocaine increase the risk for asthma exacerbations and decreased pulmonary function; marijuana is associated with wheezing, cough, and sputum production.

Severe Asthma Risk Increased From Aspergillus fumigatus Sensitization

Severe Asthma Risk Increased From Aspergillus fumigatus Sensitization

Sensitization to Aspergillus fumigatus increased the risk for severe asthma.

COPD Severity May Be Affected by Collagen Biomarker Remodeling

COPD Severity May Be Affected by Collagen Biomarker Remodeling

Collagen biomarkers were significantly higher at extreme exacerbations, and were also associated with circulating adrenomedullin.

Fewer Asthma Exacerbations With LABA Plus Inhaled Glucocorticoid

Fewer Asthma Exacerbations With LABA Plus Inhaled Glucocorticoid

Combination therapy with a long-acting β2-agonist plus an inhaled glucocorticoid for asthma was not associated with a significantly higher risk for serious asthma-related events compared with an inhaled glucocorticoid alone.

Childhood Respiratory Risk Factor Profiles Predict Lung Function, COPD

Childhood Respiratory Risk Factor Profiles Predict Lung Function, COPD

Frequent asthma, bronchitis, allergy demonstrated the strongest association with , lower FEV1, lower FEV1/forced vital capacity, and increased risk for COPD.

Cytokine Profiles of Pregnant Women Predict Asthma in Children

Cytokine Profiles of Pregnant Women Predict Asthma in Children

Cytokines produced by mitogen-stimulated immune cells from pregnant women without asthma were shown to be associated with the development of asthma in their children.

Dexamethasone Ineffective for Prevention of Acute Mountain Sickness in COPD

Dexamethasone Ineffective for Prevention of Acute Mountain Sickness in COPD

Dexamethasone was not effective in reducing the incidence of acute mountain sickness and altitude-related adverse health effects in individuals with mild to moderate COPD.

CDC: Wildfire Smoke Poses Health Risks

CDC: Wildfire Smoke Poses Health Risks

The US Centers for Disease Control offers steps to minimize exposure to wildfire smoke, particularly for those with chronic conditions.

Free Vitamin D3 Inferior to Total Concentrations in Predicting Asthma Response

Free Vitamin D3 Inferior to Total Concentrations in Predicting Asthma Response

No associations were found between free concentration vitamin D3 levels and treatment failure or exacerbation rates in adults with asthma

Inhaled IL-13 Monoclonal Antibody Inhibits IL-13 in Animal Asthma Model

Inhaled IL-13 Monoclonal Antibody Inhibits IL-13 in Animal Asthma Model

The eFlow® nebulizer delivered CDP7766 without evidence of degradation, loss of potency, aggregation, or formation of particulates in a model of asthma in cynomolgus macaques.

Umeclidinium/Vilanterol Efficacy Assessed in Elderly COPD Patients

Umeclidinium/Vilanterol Efficacy Assessed in Elderly COPD Patients

Study authors performed a post hoc pooled analysis of data from 10 trials to assess the safety and efficacy of umeclidinium/vilanterol in elderly symptomatic patients with COPD.

Anti-IL-5 Therapy Eligibility Characteristics Examined in Adult-Onset Asthma

Anti-IL-5 Therapy Eligibility Characteristics Examined in Adult-Onset Asthma

Patients with severe asthma were more often current smokers at diagnosis and had higher body mass index at follow-up compared with patients with nonsevere asthma and anti-IL-5 therapy-eligible asthma.

GERD and Nasal Symptoms Affect Bronchitis Symptom Severity in COPD

GERD and Nasal Symptoms Affect Bronchitis Symptom Severity in COPD

Gastroesophageal reflux disease is associated with an increase in bronchitis symptoms in patients with COPD.

Prolonged Leisure-Time Sitting Tied to Increased COPD Mortality Risk

Prolonged Leisure-Time Sitting Tied to Increased COPD Mortality Risk

Increase in all-cause, cardiovascular disease, cancer, diabetes, kidney disease, suicide, and COPD mortality.

FDA Approves Zephyr Endobronchial Valve for Treating Severe Emphysema

FDA Approves Zephyr Endobronchial Valve for Treating Severe Emphysema

The approval was based on results from a multicenter study (LIBERATE) of 190 patients with severe emphysema.

Use of Palliative Care, Oxygen Therapy Increasing for COPD

Use of Palliative Care, Oxygen Therapy Increasing for COPD

For patients with advanced COPD, the use of formal palliative care services and long-term oxygen therapy has increased but remains low.

Patient Engagement in Asthma Treatment Plans May Improve Quality of Life

Patient Engagement in Asthma Treatment Plans May Improve Quality of Life

Older adults with asthma and a greater desire for involvement in decision making have higher asthma-related quality of life.

Azithromycin Reduced Pulmonary Exacerbation Risk in Cystic Fibrosis

Azithromycin Reduced Pulmonary Exacerbation Risk in Cystic Fibrosis

Compared with placebo, the risk for a pulmonary exacerbation was reduced by 44% in participants with cystic fibrosis who received azithromycin.

Aspergillus Common in Bronchiectasis Pulmonary Mycobiome, Associated With Exacerbations

Aspergillus Common in Bronchiectasis Pulmonary Mycobiome, Associated With Exacerbations

Bronchiectasis-associated genera included Aspergillus, Cryptococcus, Clavispora, Botrytis, and Alternaria.

Obstructive Sleep Apnea in Asthma: Gaining Control by Losing Weight

Obstructive Sleep Apnea in Asthma: Gaining Control by Losing Weight

Poor control of asthma and obstructive sleep apnea can feed off one another, according to Michelle Zeidler, MD, pulmonologist at the University of California, Los Angeles, and director of the UCLA Sleep Fellowship Program.

Clinical Effect of Emphysema in Individuals With HIV

Clinical Effect of Emphysema in Individuals With HIV

The clinical significance of emphysema was greater in people living with HIV vs those without HIV.

COPD End-of-Life Management Strategies: Use Could Be Expanded

COPD End-of-Life Management Strategies: Use Could Be Expanded

The use of formal palliative care services among patients with chronic obstructive pulmonary disease increased by 1% per year, going from 5.3% in 2004 to 14.3% in 2014.

Asthma Risk Increased With Early-Onset Persistent Bronchial Hyperresponsiveness

Asthma Risk Increased With Early-Onset Persistent Bronchial Hyperresponsiveness

Children with the early-onset persistent bronchial hyperresponsiveness phenotype had the highest blood eosinophil count and total serum IgE levels as well as sensitization rates.

Subcutaneous Immunotherapy Shows Promise for Allergic Asthma Exacerbations

Subcutaneous Immunotherapy Shows Promise for Allergic Asthma Exacerbations

The mean rate of exacerbations declined significantly after 1 year of subcutaneous immunotherapy in children with moderate to severe allergic asthma exacerbations.

Asthma Exacerbation, Treatment Failure Prevention During Step-Down Therapy

Asthma Exacerbation, Treatment Failure Prevention During Step-Down Therapy

A hospital emergency department visit in the prior year was associated with subsequent asthma treatment failure.

Respiratory Viruses Linked to Treatment Failure in Asthma Exacerbations

Respiratory Viruses Linked to Treatment Failure in Asthma Exacerbations

Respiratory pathogens were associated with an increased risk for treatment failure in children with asthma exacerbations.

Tralokinumab Ineffective for Eosinophilic Airway Inflammation in Asthma

Tralokinumab Ineffective for Eosinophilic Airway Inflammation in Asthma

Tralokinumab did not have a significant effect on eosinophilic airway inflammation in moderate to severe asthma that was inadequately controlled on inhaled corticosteroids.

COPD Education Program Improved Patient Knowledge of Disease

COPD Education Program Improved Patient Knowledge of Disease

There was as significant change in Bristol COPD Knowledge Questionnaire scores in patients who received a brief education program at the time of an acute exacerbation of COPD.

Stroke, MI Risk Increased After Severe COPD Exacerbations

Stroke, MI Risk Increased After Severe COPD Exacerbations

Acute COPD exacerbations were associated with an increased risk for myocardial infarction and ischemic stroke.

Viruses not linked to asthma exacerbation severity

Identified viral pathogens were not associated with asthma exacerbation severity, but were linked to increased treatment failure.

Immune-Response Cluster in Infant Respiratory Syncytial Virus Linked With Recurrent Wheeze

Immune-Response Cluster in Infant Respiratory Syncytial Virus Linked With Recurrent Wheeze

A nasal immune-response pattern characterized by lower non-interferon antiviral immune response mediators and higher type 2 and type 17 cytokines was significantly associated with recurrent wheeze at 1 year.

Budesonide-formoterol as needed superior to terbutaline in mild asthma: The SYGMA trial

In patients with mild asthma, use of the inhaled combined corticosteroid and beta agonist budesonide-formoterol as needed was superior to terbutaline as needed with respect to electronically recorded weeks of well-controlled asthma.

Severe Emphysema Benefits From Zephyr® Endobronchial Valve Treatment

Severe Emphysema Benefits From Zephyr® Endobronchial Valve Treatment

Zephyr® Endobronchial Valve EBV® treatment improved FEV1 in patients with heterogeneous emphysema.

COPD Risk From Secondhand Smoke May Be Linked With Lung Volume Variations

COPD Risk From Secondhand Smoke May Be Linked With Lung Volume Variations

The inclusion of residual volume-to-total lung capacity ratio may add another dimension to COPD not routinely captured by standard airflow indices that could be predictive of lower maximum exercise capacity.

COPD Triple Therapy Switch to LABA/LAMA May Be Appropriate in Some Patients

COPD Triple Therapy Switch to LABA/LAMA May Be Appropriate in Some Patients

A direct de-escalation from triple therapy to indacaterol/glycopyrronium may be appropriate in patients with infrequent COPD exacerbations.

Ivacaftor Decreases Mortality, Hospitalization in Cystic Fibrosis

Ivacaftor Decreases Mortality, Hospitalization in Cystic Fibrosis

Ivacaftor decreased the risk for death, transplantation, hospitalization, and pulmonary exacerbation in patients with cystic fibrosis.

Various Perinatal Risks Associated With Maternal Asthma Diagnosis

Various Perinatal Risks Associated With Maternal Asthma Diagnosis

Women with a diagnosis of asthma may have a higher risk for preterm birth, and their infants may have an increased risk for perinatal mortality, low birth weight, fetal growth restriction, and asphyxia.

Omalizumab Inhibits Respiratory Reactions During Aspirin Desensitization

Omalizumab Inhibits Respiratory Reactions During Aspirin Desensitization

In patients with aspirin exacerbated respiratory disease, treatment with omalizumab resulted in "clinically silent" aspirin desensitization.

Asthma Exacerbation Risk With As-Needed Budesonide-Formoterol vs Maintenance Budesonide

Asthma Exacerbation Risk With As-Needed Budesonide-Formoterol vs Maintenance Budesonide

Budesonide-formoterol as needed was not inferior compared with budesonide maintenance therapy in terms of severe asthma exacerbation rates, but may be inferior for controlling symptoms.

Greater Use of Tobacco Products Among Youth With Asthma

Greater Use of Tobacco Products Among Youth With Asthma

E-cigarettes are the most commonly used product in middle and high school students with or without asthma.

Effectiveness of Budesonide-Formoterol vs Terbutaline in Asthma Symptom Control

Effectiveness of Budesonide-Formoterol vs Terbutaline in Asthma Symptom Control

There was a 60% lower rate of severe asthma exacerbations in individuals treated with budesonide-formoterol compared with individuals treated with terbutaline as needed.

C-Reactive Protein as a Biomarker for CAP in Bronchiectasis

C-Reactive Protein as a Biomarker for CAP in Bronchiectasis

Although clinical presentation was similar in both community-acquired pneumonia and non-pneumonia exacerbations, CRP, glucose, and leukocytes were higher in the former vs the latter.

Potential COPD Pulmonary Vascular Phenotype Associated With Poor Outcomes

Potential COPD Pulmonary Vascular Phenotype Associated With Poor Outcomes

A definition of a pulmonary vascular phenotype of chronic obstructive pulmonary disease has been proposed.

Asthma-Associated Chemicals in Hair Products for Black Women Raise Concerns

Asthma-Associated Chemicals in Hair Products for Black Women Raise Concerns

Chemicals linked with endocrine disruption and asthma identified in hair products used by black women and children.

Budesonide Improved Epithelial Barrier Function in Asthma

Budesonide Improved Epithelial Barrier Function in Asthma

Researchers evaluated barrier dysfunction by exposing viral models to budesonide, montelukast, formoterol, or a combination.

Inhaled Interferon-Beta 1a Does Not Reduce Severe Asthma Exacerbations

Inhaled Interferon-Beta 1a Does Not Reduce Severe Asthma Exacerbations

Inhaled interferon-beta 1 a did not significantly reduce acute asthma exacerbations during respiratory viral infections.

E-Cigarette Use Associated With Increased Risk for COPD

E-Cigarette Use Associated With Increased Risk for COPD

Using e-cigarettes every day or some days increased the likelihood of developing chronic obstructive pulmonary disease.

Longer Hospital Stay, Higher Costs With Unwarranted Antibiotics in Asthma Exacerbations

Longer Hospital Stay, Higher Costs With Unwarranted Antibiotics in Asthma Exacerbations

Longer stay and higher costs were associated with antibiotic administration in adults hospitalized for an asthma exacerbation without documented evidence of a lung infection.

COPD Frequently Misdiagnosed, Undiagnosed in Individuals With or Without HIV

COPD Frequently Misdiagnosed, Undiagnosed in Individuals With or Without HIV

In this study, researchers examined the appropriateness of diagnosis and treatment of chronic obstructive pulmonary disease in individuals with and without HIV.

Morning vs Evening ICS Dosing in Asthma: Efficacies Compared

Morning vs Evening ICS Dosing in Asthma: Efficacies Compared

Inhaled corticosteroids for asthma dosed once daily in the evening appeared to offer some benefit in trough FEV1 and morning peak expiratory flow.

Anxiety, Depression Associated With Poor Self-Perceived Asthma Control

Anxiety, Depression Associated With Poor Self-Perceived Asthma Control

Investigators conducted a prospective survey to examine the association between asthma symptom severity and symptoms of depression and anxiety.

Overweight, Obesity Linked to Asthma Development in Children and Adolescents

Overweight, Obesity Linked to Asthma Development in Children and Adolescents

Overweight or obese children are more likely to develop new onset asthma compared with normal weight controls.

Antibiotic Use During Pregnancy May Increase Risk for Childhood Asthma

Antibiotic Use During Pregnancy May Increase Risk for Childhood Asthma

Researchers examined the association of timing, frequency, and class of antibiotic use during pregnancy on the development of childhood asthma.

Mortality Rates in Extrafine ICS-Containing vs ICS-Free Medications in COPD

Mortality Rates in Extrafine ICS-Containing vs ICS-Free Medications in COPD

The pooled safety analysis included data from the TRILOGY, TRINITY, and TRIBUTE studies.

Sertraline Not Beneficial for Symptomatic Chronic Breathlessness

Sertraline Not Beneficial for Symptomatic Chronic Breathlessness

Sertraline does not prove to be beneficial for relief of chronic breathlessness.

Incident Diuretic Use May Increase Adverse Events in COPD

Incident Diuretic Use May Increase Adverse Events in COPD

Incident diuretic use was associated with increased rates of respiratory-related morbidity and mortality in older adults with chronic obstructive pulmonary disease.

Efficacy, Safety of Dupilumab in Corticosteroid-Dependent Severe Asthma

Efficacy, Safety of Dupilumab in Corticosteroid-Dependent Severe Asthma

Subcutaneous dupilumab significantly reduced the use of oral corticosteroids in patients with corticosteroid-dependent severe asthma.

Lung Function in Severe Asthma Improved With Benralizumab

Lung Function in Severe Asthma Improved With Benralizumab

Peak expiratory flow increases were greater with benralizumab than placebo in patients with severe eosinophilic asthma.

Asthma Risk Increased for Premenopausal Women Using Oral Contraceptives

Asthma Risk Increased for Premenopausal Women Using Oral Contraceptives

Oral contraceptive use in women of reproductive age may increase the risk for lifetime asthma.

Vitamin D Supplementation Improves Asthma Control

Vitamin D Supplementation Improves Asthma Control

In individuals with asthma and vitamin D deficiency, vitamin D supplementation improved asthma control.

Macrolides for Asthma Management: An Updated Review

Macrolides for Asthma Management: An Updated Review

While macrolides had no direct effect on lung function, their use significantly improved asthma control and quality of life in patients with asthma.

Prevalence of Obese, Allergic Asthma Phenotypes Examined in US Children

Prevalence of Obese, Allergic Asthma Phenotypes Examined in US Children

The study authors examined data obtained from the 2007-2008 National Survey of Children's Health (NSCH) to determine the prevalence, risk factors, as well as the severity of asthma phenotypes.

Most Concerning Med Issues Explored Among Youth With Asthma

Most Concerning Med Issues Explored Among Youth With Asthma

The study authors reported, "The most commonly reported problems by youth were: (a) hard to remember when to take the asthma medication (54%) and (b) hard to use asthma medication at school (34%)."

Feasibility of At-Home Use Injectable Tx for Severe Asthma Assessed

Feasibility of At-Home Use Injectable Tx for Severe Asthma Assessed

Of the total 573 APFS dispensed, 1 malfunctioned and 1 was considered nonfunctional because it was not returned. The study authors also reported that patient-use error only led to 2 unsuccessful at-home administrations.

ICS Therapy May Not Be Enough for Asthma Patients With Elevated Eosinophils

ICS Therapy May Not Be Enough for Asthma Patients With Elevated Eosinophils

The study aimed to determine the association between ICS therapy adherence and the occurrence of asthma exacerbations in patients with high blood eosinophil levels.

Type 2 Biomarkers May Predict Exacerbations in Severe Refractory Asthma

Type 2 Biomarkers May Predict Exacerbations in Severe Refractory Asthma

The positive association between type 2 biomarkers and severe exacerbations in severe refractory asthma may not extend to mild to moderate asthma.

Assessing Depression Following Inpatient COPD Rehabilitation

Assessing Depression Following Inpatient COPD Rehabilitation

PHQ-9 and PHQ-2 show factorial validity, invariance, and reliability for measuring depression in patients with chronic obstructive pulmonary disease.

Low Neighborhood Walkability Increases Risk of Asthma in Kids

Low Neighborhood Walkability Increases Risk of Asthma in Kids

Children living in neighborhoods with low walkability are at increased risk of asthma.

COPD, Asthma, or Asthma COPD Overlap Syndrome: Diagnostic Challenges

COPD, Asthma, or Asthma COPD Overlap Syndrome: Diagnostic Challenges

Emerging guidelines for diagnosing and treating asthma COPD overlap syndrome will help clinicians better manage patients and prevent serious adverse effects.

Palliative Care Consult Can Cut Hospital Costs in Seriously Ill

Palliative Care Consult Can Cut Hospital Costs in Seriously Ill

Palliative care consultation was linked to a reduction in hospital costs for hospitalized adults with serious illness, such as COPD.

Pediatric Asthma Outcomes With Physician Cultural Communication Training

Pediatric Asthma Outcomes With Physician Cultural Communication Training

Physician asthma care education Plus training resulted in improvements in provider confidence, perceived skill in communicating cross culturally, and short-term asthma-specific outcomes.

Asthma Care Program Improves Provider Documentation, Clinical Measures

Asthma Care Program Improves Provider Documentation, Clinical Measures

An asthma care program improved implementation of guidelines as well as provider documentation in 65 community centers in 4 states that serve patients with asthma.

Survival Predictors When Life Support Is Withheld in ICU

Survival Predictors When Life Support Is Withheld in ICU

Survival at 6 months was significantly associated with acute respiratory failure and history of COPD.

Current Smokers With Severe Asthma Distinguished by Sputum Proteomics

Current Smokers With Severe Asthma Distinguished by Sputum Proteomics

Patients with severe asthma who were current smokers were distinguishable from ex-smokers based on their sputum proteomic level of colony stimulating factor 2.

Pneumonia Risk in Severe COPD Linked to Elevated Eosinophil Count

Pneumonia Risk in Severe COPD Linked to Elevated Eosinophil Count

A higher proportion of patients with COPD and a blood eosinophil count of ≥0.34×109/L had elevated markers of low-grade systemic inflammation regardless of forced expiratory volume in 1 second.

Children With Status Asthmaticus Do Not Benefit From Magnesium Sulfate

Children With Status Asthmaticus Do Not Benefit From Magnesium Sulfate

Children with status asthmaticus who received magnesium sulfate therapy were on continuous albuterol for a longer duration.

Early Readmission Factors in COPD After Hospitalization for Acute Exacerbation

Early Readmission Factors in COPD After Hospitalization for Acute Exacerbation

Readmission rates were highest during the first 72 hours after admission for an acute exacerbation of chronic obstructive pulmonary disease.

Addition of Olodaterol to Tiotropium Does Not Significantly Reduce COPD Exacerbations

Addition of Olodaterol to Tiotropium Does Not Significantly Reduce COPD Exacerbations

Adding olodaterol to tiotropium did not significantly reduce exacerbations in patients with chronic obstructive pulmonary disease as much as researchers had anticipated.

Asthma and COPD Overlap Associated With Higher Risk for Sleep-Related Symptoms

Asthma and COPD Overlap Associated With Higher Risk for Sleep-Related Symptoms

Asthma and COPD overlap linked to higher prevalence of sleep-related symptoms, including difficulty falling asleep and maintaining sleep, early-morning awakening, and excessive daytime sleepiness.

Trelegy Ellipta Gains Expanded COPD Indication, Loses Boxed Warning

Trelegy Ellipta Gains Expanded COPD Indication, Loses Boxed Warning

The drug consists of fluticasone furoate, an inhaled corticosteroid (ICS), umeclidinium, a long-acting muscarinic antagonist, and vilanterol, a long-acting beta2-adrenergic agonist (LABA), delivered via an Ellipta dry powder inhaler.

Early Child Care Attendance and Asthma, Wheeze Risk: What's the Link?

Early Child Care Attendance and Asthma, Wheeze Risk: What's the Link?

Early child care attendance increased the risk for wheeze in children ≤2 years of age but decreased the risk for asthma in children 3 to 5 years of age.

Transcatheter vs Surgical Aortic Valve Replacement in COPD

Transcatheter vs Surgical Aortic Valve Replacement in COPD

In patients with COPD, transcatheter aortic valve replacement was associated with fewer respiratory-related complications than surgical aortic valve replacement.

Breathing New Life Into COPD and Asthma Therapy With Statins

Breathing New Life Into COPD and Asthma Therapy With Statins

Statins have anti-inflammatory and anti-oxidative effects, which could reduce exacerbations of both asthma and chronic obstructive pulmonary disease.

Triple Therapy Tied to Reduced Rate of COPD Exacerbations

Triple Therapy Tied to Reduced Rate of COPD Exacerbations

Triple therapy with fluticasone furoate, umeclidinium, and vilanterol was associated with a lower rate of exacerbations in chronic obstructive pulmonary disease.

COPD Risk in Middle-Age: The 3-Way Interaction of Asthma, Smoking, and Measles

COPD Risk in Middle-Age: The 3-Way Interaction of Asthma, Smoking, and Measles

A childhood measles infection may increase the risk for post-bronchodilator airflow obstruction in middle-age adults via its interaction with asthma and smoking.

Cardiovascular Complications of COPD

Cardiovascular Complications of COPD

A 55-year-old man with chronic obstructive pulmonary disease reports having some mild chest pain.

Early Asthma Symptoms Linked to Lung Function in Adolescents Born Preterm

Early Asthma Symptoms Linked to Lung Function in Adolescents Born Preterm

Preterm-born children had significantly more frequent preschool wheeze compared with children born at term.

No significant benefit of long-acting muscarinic antagonists over long-acting beta-agonists in reducing exacerbation risk in uncontrolled, persistent asthma

Adjunct long-acting muscarinic antagonist (LAMA) use with corticosteroids was associated with reduced exacerbation risk compared with placebo in patients with uncontrolled, persistent asthma. However, LAMA, long-acting beta-agonist (LABA), and inhaled corticosteroids (triple therapy) were not associated with lower risk for exacerbations compared with LABA and inhaled corticosteroids alone.

Perioperative Risk Assessment in a Patient With COPD

Perioperative Risk Assessment in a Patient With COPD

A 64-year-old man with chronic obstructive pulmonary disease, diabetes, chronic kidney disease, and morbid obesity seeks preoperative approval for femoral popliteal bypass surgery.

Fixed-Dosed Dual Bronchodilators for COPD: Overview and Clinician Interview

Fixed-Dosed Dual Bronchodilators for COPD: Overview and Clinician Interview

Treating chronic obstructive pulmonary disease remains challenging, particularly in terms of choosing the appropriate fixed-dose combination bronchodilator.

COPD Risk Predicted by Large Airway Dimensions on Computed Tomography

COPD Risk Predicted by Large Airway Dimensions on Computed Tomography

Greater Pi10 was associated with incident spirometry-defined chronic obstructive pulmonary disease in a general population-based sample without clinical lung disease.

Lung Function in Cystic Fibrosis Affected by Sputum Viscoelasticity and Poor Clearance

Lung Function in Cystic Fibrosis Affected by Sputum Viscoelasticity and Poor Clearance

Sputum viscoelastic properties were associated with lung function and disease status in patients with cystic fibrosis.

Asthma Exacerbation Risk Lower With SMART Therapy

Asthma Exacerbation Risk Lower With SMART Therapy

In patients with persistent asthma, single maintenance and reliever therapy was associated with a lower risk for exacerbations compared with inhaled corticosteroids as controller therapy and short-acting beta-agonists as relief therapy.

Tai Chi Helps Improve Respiratory Function in COPD

Tai Chi Helps Improve Respiratory Function in COPD

Tai chi found to be as effective as pulmonary rehabilitation for patients with chronic obstructive pulmonary disease.

Debating Noninvasive vs Invasive Ventilation in Acute Exacerbations of COPD

Debating Noninvasive vs Invasive Ventilation in Acute Exacerbations of COPD

It is still not known whether differences in mortality rates between patients who receive noninvasive vs invasive ventilation for acute exacerbations of COPD can be attributed to less severe disease or other factors.

Omalizumab Effective in Severe Allergic Asthma, Regardless of Eosinophil Level

Omalizumab Effective in Severe Allergic Asthma, Regardless of Eosinophil Level

Regardless of blood eosinophil count, omalizumab was an effective treatment in adult and pediatric patients with severe allergic asthma.

Distinct Lung Function Trajectories Associated With COPD Risk

Distinct Lung Function Trajectories Associated With COPD Risk

Researchers identified 6 distinct FEV1 lung function trajectories, 3 of which were responsible for 75% of the COPD burden.

Novel Cystic Fibrosis Treatment Granted Fast Track Status

Novel Cystic Fibrosis Treatment Granted Fast Track Status

Proteostasis Therapeutics is developing the combination treatment which includes a novel transmembrane conductance regulator (CFTR) amplifier (PTI-428), a third generation corrector (PTI-801) and a potentiator (PTI-808).

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