The Depression, Anxiety, and Stress Scale (DASS-21) demonstrated validity in individuals with COPD underwent an 8-week pulmonary rehabilitation program.
When designing either biomarker-stratified or phenotype-directed protocols for asthma-related clinical trials, including a contingency plan can help manage scenarios in which phenotypes in the study sample differ in prevalence from expected values.
Adolescents with asthma who practice good sleep hygiene may experience improvements in sleep and attention span, better quality of life in school, and lower rates of dysfunction during the daytime.
Recent guidelines set forth by an interdisciplinary panel assembled by the American Thoracic Society sought to demystify primary ciliary dyskinesia and address 4 main diagnostic questions.
Children with poorly controlled asthma who underwent a home-based environmental control intervention had the same risk for repeat emergency department visits as children who did not receive the intervention.
Although uncontrolled asthma in early childhood can have enduring effects on lung development, whether the use of traditional interventions in very young pediatric patients can actually preserve pulmonary function is unclear.
All of the randomized controlled trials evaluated had successful improvements in weight or body mass index in patients with asthma.
A new study found that subfertility and the use of assisted reproductive technologies may increase the risk for asthma in offspring.
Odds of being undiagnosed with asthma are higher for girls, and Asian-Americans vs white non-Hispanics.
Digital interventions, such as web-based programs, mobile apps, and text messaging, have been found to improve asthma control and medication adherence while reducing the use of "rescue" medications.
The review showed supplementation was only effective for baseline vitamin D levels <25 nmol/L.
Hypertension and diabetes are especially prevalent comorbidities in obese patients with chronic obstructive pulmonary disease.
A new quantitative personalized tool to predict asthma development in young children predicted asthma development reliably.
Findings were seen in youth reporting asthma diagnosis and secondhand exposure to e-cigarette aerosols.
More than a fourth of teenagers with asthma reported depressive symptoms and greater symptom severity.
Influenza-positive patients have higher rates of crude mortality and critical illness vs influenza-negative patients.
Researchers examined self-reported smoking habits at age 16 years among adolescents and parents in relation to phenotypes of asthma.
Children with asthma are prescribed antibiotics at a higher rate than children without asthma.
Patients with comorbid stable COPD and chronic hypercapnic respiratory failure have improved symptoms and survival rates with high-intensity noninvasive ventilation.
Pediatric pulmonologists most often chose symptom resolution following treatment with bronchodilators as the key clinical criterion for asthma diagnosis.
The GOLD scientific committee published a report on current controversies in COPD, including the role of cigarette smoking vs biomass exposure, the role of thoracic imaging, and different treatment strategies.
ProAir Digihaler is the first digital inhaler with built-in sensors that connects to a mobile application and provides data on inhaler use to patients with asthma and chronic obstructive pulmonary disease (COPD).
The prevalence of overlap syndrome in obstructive sleep apnea and COPD in Medicare beneficiaries increased 4-fold from 2004 to 2013.
The COPD assessment test proved to be valid and reproducible in assessing the impact effect and severity of bronchiectasis symptoms in patients with COPD.
Children with asthma who had their fractional exhaled nitric oxide measured using a 6-second exhalation had consistent results that agreed with 10-second exhalation measurements.
The use of tralokinumab was not associated with oral corticosteroid-sparing effects in patients with severe asthma.
The odds of developing COPD were considerably higher in both men and women with class III obesity compared with normal weight individuals.
Mild bronchiectasis in smokers is associated with distal pulmonary vascular pruning.
In infants with cystic fibrosis, preventive inhalation with hypertonic saline during the first months of life is safe and well tolerated and results in clinical improvements, according to a new study.
Cognitive behavioral therapy interventions were statistically and clinically superior to self-help leaflets in the treatment of anxiety in patients with COPD.
The study authors aimed to assess AE risk and complications of OCS use in patients with asthma since most studies only report them in non-asthmatic patients.
The trial analyzed the antibody response of 103 asthmatic patients to the seasonal influenza vaccine.
Patients with COPD who were considered frail were more likely to have lower quality of life, increased rate and length of hospitalization, and a higher rate of mortality.
A 12% decrease in PM2.5 concentrations would result in an economic benefit of nearly $350 million annually.
The risk for asthma and wheezing in the first 10 years of childhood have been linked to a low maternal intake of vitamins D and E.
Compared with usual care, a comprehensive 3-month program combining transition and long-term self-management support for patients with COPD led to significantly fewer COPD-related hospitalizations and greater quality of life.
Omalizumab rescue therapy produced rapid results in a patient with refractory status asthmaticus.
A strong dose-response relationship was seen in never-smokers aged 50 and older.
Including invalid data decreases the validity of multiple breath washout measurements in clinical trials involving adults with bronchiectasis.
Ottawa COPD Risk Scale is valid for predicting short-term serious outcomes for patients in the emergency department.
Blood eosinophil concentrations could be used to target patients with chronic obstructive pulmonary disease who are likely to respond to initial long-acting bronchodilator therapy.
Living in a rural community was a predictor for COPD prevalence, whether the individual had a history of smoking or was a current smoker.
The presence of COPD is linked to higher all-cause mortality and cardiac death at 24 hours in high-risk patients who present with ventricular tachyarrhythmias and sudden cardiac arrest.
A Mediterranean diet, including 2 servings of fatty fish per week, has the potential to reduce airway inflammation in children with asthma.
Decreasing alpha diversity in the microbiome profile of sputum samples of patients hospitalized with COPD acute exacerbations was associated with increased 1-year mortality.
Mepolizumab demonstrated long-term safety and efficacy in the management of severe eosinophilic asthma.
Nocturnal hypoxemia, along with COPD, increased the risk for cardiovascular events and mortality in female patients with suspected obstructive sleep apnea.
Healthcare providers should educate all patients with COPD about their flight-related risks and the need to seek medical advice before flying.
Clinicians are gaining a better understanding of how asthma and allergies are regulated by the circadian clock, which will help patients better alleviate their symptoms.
VX-445-tezacaftor-ivacaftor led to noticeable improvements in Phe508del CFTR protein function.
Bronchoscopic lung volume reduction with valve replacement shows the most promise for improving lung function, exercise tolerance, and quality of life in patients with advanced emphysema.
In the absence of overweight and obesity, 10% of all pediatric asthma cases would be avoided.
Consistent associations were observed per 5 mm Hg higher maternal blood pressures in early pregnancy with lower FEV1/FVC.
Gaps in insurance coverage increased the odds of asthma-related emergency department intervention or hospitalization and exacerbations.
The Symptom Free Days Questionnaire may not be a reliable measurement in black patients with asthma.
Children of caregivers with poor asthma knowledge more likely to have prolonged hospital stay
Compared with a combination treatment of LABA/LAMA, ICS/LABA/LAMA combination therapy was associated with a significantly greater pooled risk reduction in COPD exacerbation.
The maximum symptom day has been confirmed as a reliable, responsive, and valid tool for measuring asthma symptom control.
Few individuals hospitalized for COPD receive pulmonary rehabilitation.
Patients with both asthma and allergies had a significant increase in the number of prescriptions dispensed for controller medications.
Patients who received reslizumab experienced significantly greater improvements in each sleep-related related Asthma Quality of Life Questionnaire question score compared with placebo.
Significant improvements were seen in lung function in patients who received either dose of beclomethasone dipropionate.
The mean proportion of days covered in the fluticasone furoate/vilanterol group was significantly higher than in the budesonide/formoterol and fluticasone propionate/salmeterol groups.
By day 3, patients with severe eosinophilic asthma who received benralizumab required less use of rescue medication.
Add-on tiotropium therapy improved lung function compared with placebo in moderate asthma.
Facilitator-led sites had a higher percentage of patients who reported equal participation with their provider in making asthma treatment decisions vs the lunch-and-learn sites.
Better asthma control, as indicated by lower mean scores on the Asthma Control Questionnaire-5, were seen in both the dupilumab and placebo groups.
Three-dimensional "super clusters" in patients with COPD could play a role in the progression of COPD to emphysema.
Several asthma and allergy groups expressed "deep concern" over the recent FDA approval of Primatene MIST.
There may an increased risk for tuberculosis in patients with COPD within 3 years of inhaled corticosteroid use.
The FDA has approved Yupelri inhalation solution for the maintenance treatment of patients with COPD.
Adding VX-659 to tezacaftor and ivacaftor therapy improved lung function in patients with cystic fibrosis.
The new inhalation delivery system no longer includes CFC. It contains hydrofluroalkane (HFA) propellants and also features a built-in spray indicator and metal canister, replacing the glass container seen with the original Primatene Mist.
Higher BMI in adults was related to an increase in moderate to severe upper respiratory infections.
The ACCI includes questions about changes in asthma status, perceptions of disease burden, emergency room visits and hospitalizations, steroid use, adherence to prescribed medications, and symptom frequency.
Paradoxical bronchoconstriction is an underrecognized adverse event that can occur with administration of β2-agonist-containing inhaler formulations.
The overall rate of asthma-COPD overlap was 3.8%, with a maximum prevalence of 7.8% in Matlab, Bangladesh.
Adults with COPD treated with both inhaled corticosteroids and low-dose theophylline as adjunct therapy did not have fewer exacerbations compared with patients treated with inhaled corticosteroids only.
The use of chest radiographs in children with asthma who complain of chest pain should be limited, according to a new study.
Half of patients with COPD report use of inhaler medications that are not in alignment with the current treatment recommendations.
Air-driven bronchodilator nebulization is preferable to oxygen-driven nebulization in patients experiencing acute COPD exacerbations.
The increased occurrence of periprocedural complications in patients with COPD was largely attributed to cardiac arrest, myocardial infarctions, and no-reflows.
Children exposed to cats, dogs, goats, cockroaches, and rats while in utero were more likely to develop asthma.
Albuminuria was associated with greater lung function decline in patients with chronic obstructive pulmonary disease.
Time-series analysis based on geographic location revealed positive significant associations between asthma and influenza hospitalizations in Brooklyn and Manhattan.
The majority of study participants had rhinitis at baseline, including perennial allergic rhinitis with seasonal exacerbations, which is the most severe phenotype.
Changing to bronchodilator treatment with a metered dose inhaler in patients with mild to moderate asthma resulted in lower hospitalization rates, shorter hospital stays, and a decrease in continuous use of albuterol.
The FDA has approved Dupixent as an add-on maintenance treatment in patients with moderate-to-severe asthma aged 12 years and older with an eosinophilic phenotype or with oral corticosteroid-dependent asthma.
Cystic fibrosis transmembrane conductance regulator dysfunction is associated with worsened airway disease in patients with COPD.
Total serum bilirubin levels of 9 to 11.9 mg/dL, 12 to 14.9 mg/dL, and 15 to 17.9 mg/dL were associated with significantly greater risks for asthma in infants.
Childhood non-atopic rhinitis is associated with an increased risk for adult asthma.
No difference in mortality, but there may be an elevated risk for suicide with long-term benzodiazepine use in patients with COPD and comorbid PTSD.
Middle-aged testosterone replacement therapy users with COPD had a greater reduction in hospitalizations compared with nonusers.
The FDA has granted Orphan Drug Designation to a novel inhaled treatment that could potentially improve lung function in patients with cystic fibrosis.
The risk for obstructive lung disease was nearly 8 times greater in heavy stable smokers compared with never-smokers.
Children with asthma had a 66% higher risk for incident obesity compared with children without asthma.
Bronchial thermoplasty reduced gas trapping in individuals with asthma, particularly in patients with severe disease.
Early pulmonary rehabilitation after hospitalization for an acute exacerbation of COPD was an effective intervention for reducing mortality.
The FDA has approved updated labeling for Stiolto Respimat to include COPD exacerbation data and a revised indication.
Patients who received a discharge care bundle after being hospitalized for an acute exacerbation of COPD had a lower rate of readmission.