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Opioid use associated with increased risk of invasive pneumococcal disease

Researchers found the strongest link between prescription opioid use and the risk for invasive pneumococcal disease was present in individuals using formulations of opioids that were long-acting, highly potent, or used at a high dose.

Pneumococcal Disease Risk Linked to Opioid Use

Pneumococcal Disease Risk Linked to Opioid Use

Long-acting, high-potency, and high-dose opioids were associated with an increased risk for invasive pneumococcal disease.

Invasive Mechanical Ventilation in Severe CAP Increased Mortality Risk

Invasive Mechanical Ventilation in Severe CAP Increased Mortality Risk

Invasive mechanical ventilation in patients with severe community-acquired pneumonia appeared to increase their mortality risk.

Characteristics of Bacterial Isolates Before and After PCV13 Introduction

Characteristics of Bacterial Isolates Before and After PCV13 Introduction

Nasopharyngeal samples collected from young children with acute otitis media were analyzed for S pneumoniae, H influenzae, and Moraxella catarrhalis and compared before and after PCV13 introduction.

Characteristics Associated With Inappropriate Antibiotic Prescribing

Characteristics Associated With Inappropriate Antibiotic Prescribing

Patient, practice, and provider characteristics are associated with inappropriate antimicrobial prescribing in the outpatient setting.

FDA Approves Avycaz Supplemental NDA for Pneumonia

FDA Approves Avycaz Supplemental NDA for Pneumonia

The FDA approved the supplemental New Drug Application for Avycaz to treat adults with hospital-acquired or ventilator-associated bacterial pneumonia.

Reducing Postoperative Respiratory Complications Through Physiotherapy

Reducing Postoperative Respiratory Complications Through Physiotherapy

The preoperative physiotherapy intervention cut the incidence of postoperative pulmonary complications by 50%.

Procalcitonin-Guided Pneumonia Treatment Associated With Improved Outcomes

Procalcitonin-Guided Pneumonia Treatment Associated With Improved Outcomes

Procalcitonin may decrease mortality rates in patients with acute respiratory infections, including pneumonia.

Pneumonia in Childhood Linked to Higher Short-Term Incidence of Some Cancers

Pneumonia in Childhood Linked to Higher Short-Term Incidence of Some Cancers

Short-term incidence of leukemia, lymphoma, and brain cancer may be higher in children who were hospitalized with pneumonia.

Effect of Corticosteroids on Pneumonia-Related Mortality

Effect of Corticosteroids on Pneumonia-Related Mortality

Mortality from severe pneumonia may be significantly reduced with corticosteroids.

Incidence of Non-Ventilator Hospital-Acquired Pneumonia

Incidence of Non-Ventilator Hospital-Acquired Pneumonia

Non-ventilator hospital-acquired pneumonia is a significant burden in US acute care hospitals and poses a risk to nonelderly, non-intensive unit patients.

Intravenous Antibiotic Recalled Due to Mold

Intravenous Antibiotic Recalled Due to Mold

AuroMedics Pharma announced a voluntary recall of 1 lot of Linezolid injection after a batch found contained mold.

Predictors of Pneumonia in Adults With Lower Respiratory Tract Infections

Predictors of Pneumonia in Adults With Lower Respiratory Tract Infections

Researchers identified 4 specific symptoms that could be the basis for a pneumonia diagnosis.

Adult Vaccinations: Improving Public Perception and Awareness

Adult Vaccinations: Improving Public Perception and Awareness

Educational campaigns regarding the value of vaccines should integrate social psychological considerations with health communication principles.

The Potential Pitfalls of Machine Learning Algorithms in Medicine

The Potential Pitfalls of Machine Learning Algorithms in Medicine

The ability of machine learning programs to diagnose medical conditions and predict outcomes is discussed in an opinion article.

Pneumonia in Pediatric Patients: Assessing Reliability of Signs and Symptoms

Pneumonia in Pediatric Patients: Assessing Reliability of Signs and Symptoms

No single finding appears to reliably predict a pneumonia diagnosis in pediatric patients younger than 5 years of age.

Usefulness of CHEST 2006 Cough Classifications

Usefulness of CHEST 2006 Cough Classifications

The 2006 CHEST management algorithms for acute, subacute, and chronic cough appear to be useful in treating adults globally.

Nebulized Antibiotics May Prevent Ventilator-Associated Pneumonia Occurrence

Nebulized Antibiotics May Prevent Ventilator-Associated Pneumonia Occurrence

Prophylactic antibiotics administered to patients who were mechanically ventilated reduced the rate of ventilator-associated pneumonia.

Inhaled Corticosteroids Do Not Increase Risk for Pneumonia in COPD

Inhaled Corticosteroids Do Not Increase Risk for Pneumonia in COPD

In contrast to previous study findings, inhaled corticosteroids do not appear to increase risk for pneumonia in patients with COPD with moderate airflow limitation.

Empiric Antibiotic Therapy in Hospital-Acquired and Ventilator-Associated Pneumonia

Empiric Antibiotic Therapy in Hospital-Acquired and Ventilator-Associated Pneumonia

Strictly following empirical antimicrobial treatment guidelines in patients with hospital-acquired or ventilator-associated pneumonia may result in overtreatment with antibiotics.

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