Compared with patients with a negative CT, patients with chronic thromboembolic pulmonary hypertension tended to have lower dual-energy computed tomography-based parenchymal attenuation in Hounsfield unit.
The use of inferior vena cava filters may increase the risk for 30-day and 1-year mortality in elderly patients with acute pulmonary embolism.
Electronic clinical decision support systems in emergency departments can help physicians make decisions regarding site-of-care for patients with acute pulmonary embolism.
The diagnostic strategy includes clinical probability assessment, D-dimer, lower-limb compression ultrasound, and CT pulmonary angiography.
A 25-year-old man complaining of chest pain and with evidence of significant chest trauma presented to the emergency department after suffering an accident while riding an all-terrain vehicle.
D-dimer can serve as a sensitive test for pulmonary embolism in adolescents.
A number of risk factors were associated with chronic thromboembolic pulmonary hypertension, including, age >70 years, female gender, and pulmonary embolism at first venous thromboembolism.
Rates of pulmonary embolism ranged from 3.3% to 29.1% in patients with a clinical diagnosis of an acute exacerbation of COPD.
Patients treated for acute pulmonary embolism with direct oral anticoagulants at doses against manufacturer recommendations had a higher rate of major bleeding events.
At the end of 6 months, the rate of VTE recurrence was 4% among rivaroxaban patients vs 11% in the dalteparin arm (hazard ratio [HR] 0.43, 95% CI: 0.19 to 0.99).
D-dimer test adjustment based on pretest probability results may be a safe option to reduce the need for imaging during evaluation for pulmonary embolism.
Copeptin may be useful for identifying normotensive patients with pulmonary embolism who have a higher risk for an adverse outcome.
Varicose veins may increase the risk for pulmonary embolism and peripheral artery disease.
Observation in the emergency department followed by outpatient management with anticoagulation may be appropriate treatment for some patients with low-risk pulmonary embolism.
Although the Wells and revised Geneva scores are used in the general population to predict pulmonary embolism, researchers found they were not reliable in pregnant and postpartum women.
A clinical trial is underway to assess the safety and efficacy of dabigatran in intermediate-risk pulmonary embolism after completing 72 hours of heparin therapy.
Prospective validation research is needed before these clinical predictors of pediatric PE can become guidelines.
A systematic review evaluated whether catheter-directed thrombolysis improved outcomes in patients with intermediate-risk pulmonary emboli.
The use of veno-arterial extracorporeal membrane oxygenation as bridge therapy for massive pulmonary embolism may allow clinicians to better triage patients to appropriate destination therapy.
Influenza vaccination does not increase the risk for venous thromboembolism in patients older than 50 years of age.
Similar short-term outcomes were seen in patients with saddle and nonsaddle pulmonary embolism.
Charleston comorbidity index is an independent predictor of mortality in patients with hemodynamically stable pulmonary embolism.
Patients with either central or peripheral pulmonary embolism had positive outcomes with surgical pulmonary embolectomy for peripheral distribution of thrombus.
Obstructive sleep apnea increases patients' risk for recurrent pulmonary embolism following cessation of oral anticoagulation therapy.