Respiratory Tract Infection
Advanced diagnostic platforms to identify viruses can help patients with severe lower respiratory tract infections avoid unnecessary diagnostic testing, reduce antibiotic use, and initiate antiviral therapy.
Nasopharyngeal detection and increased abundance of Lactobacillus during acute respiratory infection with respiratory syncytial virus was associated with a lower risk for childhood wheezing illnesses.
Nebulized hypertonic saline may decrease length of hospital stay and improve clinical severity scores in infants with acute bronchiolitis.
Respiratory viruses were identified in 55% of febrile infants; those older than 28 days had a lower risk of bacterial infection when they tested positive for a respiratory virus.
For febrile infants, human rhinovirus is common, and detection does not alter risk of concomitant urinary tract infection or invasive bacterial infection.
A gas-capillary column ion mobility spectrometer may be a feasible and noninvasive tool for clinicians to diagnose respiratory tract infections in hospitalized patients.