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CT Honeycombing in Interstitial Lung Disease Linked to Higher Mortality Rates

CT Honeycombing in Interstitial Lung Disease Linked to Higher Mortality Rates

Patients with interstitial lung disease who had honeycombing on chest computed tomography had higher mortality rates than patients without honeycombing.

Pirfenidone Slows Long-Term Progression of Idiopathic Pulmonary Fibrosis

Pirfenidone Slows Long-Term Progression of Idiopathic Pulmonary Fibrosis

Fewer than 25% of patients with idiopathic pulmonary fibrosis who were treated with the antifibrotic drug pirfenidone showed signs of disease progression.

Biomarkers Predictive of Systemic Sclerosis-Interstitial Lung Disease Identified

Biomarkers Predictive of Systemic Sclerosis-Interstitial Lung Disease Identified

Lung‐epithelial‐derived surfactant protein has been identified as a biomarker of systemic sclerosis-interstitial lung disease.

Summary of 2018 Idiopathic Pulmonary Fibrosis Diagnostic Guidelines

Summary of 2018 Idiopathic Pulmonary Fibrosis Diagnostic Guidelines

A new clinical practice guidelines summary for clinicians regarding idiopathic pulmonary fibrosis has been released, which describes clinical manifestations and diagnostic interventions for the disease.

New Idiopathic Pulmonary Fibrosis Treatment Safe, Likely Effective

New Idiopathic Pulmonary Fibrosis Treatment Safe, Likely Effective

Oral PBI-4050 alone or in combination with nintedanib or pirfenidone was well tolerated and associated with no serious adverse events in patients with idiopathic pulmonary fibrosis.

Antibiotics Often Inappropriately Prescribed for Bronchiolitis

Antibiotics Often Inappropriately Prescribed for Bronchiolitis

In almost 70% of bronchiolitis cases, antibiotics were prescribed with no concomitant infection.

Systemic Sclerosis-Associated PAH Genomic Signature Differs From ILD

Systemic Sclerosis-Associated PAH Genomic Signature Differs From ILD

Systemic sclerosis-associated pulmonary hypertension and systemic sclerosis-associated interstitial lung disease exhibit similar but distinct gene expression profiles.

Restrictive, Obstructive Lung Disease Linked to Dementia Risk

Restrictive, Obstructive Lung Disease Linked to Dementia Risk

Associations were seen for both Alzheimer's disease-related dementia and cerebrovascular etiologies.

Prophylactic Azithromycin Beneficial in Idiopathic Pulmonary Fibrosis

Prophylactic Azithromycin Beneficial in Idiopathic Pulmonary Fibrosis

Prophylactic azithromycin may reduce hospital stays and the need for rescue antibiotics in patients with idiopathic pulmonary fibrosis.

Pediatric ARDS Identification, Stratification With PALICC Definition

Pediatric ARDS Identification, Stratification With PALICC Definition

Using the Pediatric Acute Lung Injury Consensus Conference definition of pediatric acute respiratory distress syndrome identifies more patients with the condition than the Berlin definition.

Hypersensitivity Pneumonitis Prognosis by Phenotype

Hypersensitivity Pneumonitis Prognosis by Phenotype

Compared with idiopathic pulmonary fibrosis, nonhoneycomb hypersensitivity pneumonitis phenotypes are associated with greater improvements in percent-predicted forced vital capacity.

Cholestenoic Acid: A Potential Biomarker for Acute Respiratory Distress Syndrome

Cholestenoic Acid: A Potential Biomarker for Acute Respiratory Distress Syndrome

Cholestenoic acid may represent a unique and clinically important biomarker for acute respiratory distress syndrome.

High-Resolution CT Useful in Systemic Sclerosis-Associated ILD Screening

High-Resolution CT Useful in Systemic Sclerosis-Associated ILD Screening

Clinicians should incorporate chest high-resolution computed tomography when screening patients with systemic sclerosis-associated interstitial lung disease even when pulmonary function tests results are normal.

Radiography Still Common in Pediatric Bronchiolitis Despite AAP Guidelines

Radiography Still Common in Pediatric Bronchiolitis Despite AAP Guidelines

Despite recommendations made by the American Academy of Pediatrics, the use of radiography in pediatric bronchiolitis has not decreased.

High IL-18 Levels Associated With Interstitial Lung Disease in RA

High IL-18 Levels Associated With Interstitial Lung Disease in RA

Researchers investigated whether increased IL-18 levels were associated with interstitial lung disease in rheumatoid arthritis.

Case: Severe ARDS Following Hydrochlorothiazide Administration

Case: Severe ARDS Following Hydrochlorothiazide Administration

A recent report published in The Journal of Emergency Medicine describes the case of a male patient who experienced HCTZ-induced pulmonary edema that was complicated by ARDS.

Measuring Physical Activity Levels in Fibrotic Interstitial Lung Disease

Measuring Physical Activity Levels in Fibrotic Interstitial Lung Disease

The International Physical Activity Questionnaire long form is considered valid and consistent for measuring levels of physical activity in patients with fibrotic interstitial lung disease.

Early Oseltamivir Use Linked to Clinical Benefits in Influenza Complicating ARDS

Early Oseltamivir Use Linked to Clinical Benefits in Influenza Complicating ARDS

Patients with acute respiratory distress syndrome and confirmed influenza diagnosis treated ≤6 hours with oseltamivir had reduced length of hospital stay and a lower rate of mortality.

Trends in Sarcoidosis-Related Hospitalizations in the United States

Trends in Sarcoidosis-Related Hospitalizations in the United States

Blacks experience a significantly higher rate of sarcoidosis-associated hospitalizations compared with whites.

COPD, ILD Do Not Benefit More From Bilateral Transplantation Only Listing

COPD, ILD Do Not Benefit More From Bilateral Transplantation Only Listing

No meaningful associations were detected in procedural listing preferences and survival outcomes in patients with COPD or interstitial lung disease awaiting lung transplant.

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