Dupilumab Gets FDA Priority Review for Atopic Dermatitis in Children
The FDA has accepted for Priority Review the supplemental Biologics License Application (sBLA) for dupilumab as an add-on maintenance treatment for pediatric atopic dermatitis.
Atopic Dermatitis
Dupilumab Associated With Favorable Benefit/Risk Ratio for Atopic Dermatitis
This study supports the use of dupilumab as a systemic treatment for long-term management of moderate to severe AD without routine laboratory monitoring in clinical practice.
Long-Term Dupilumab Therapy Shows Sustained Improvements in Atopic Dermatitis Symptoms
The safety and efficacy profile from this study supports the role of dupilumab as continuous long-term treatment for patients with moderate to severe atopic dermatitis.
Asthma, Atopic Dermatitis May Predispose to Behavioral and Emotional Problems
Although atopic dermatitis in infancy was not associated with later behavioral problems, at 6.5 years old, children who experienced asthma or atopic dermatitis symptoms within the past year were at increased risk for concomitant emotional problems.
Atopic Dermatitis Associated With Food Allergy Is Unique Endotype
Children with both atopic dermatitis and food allergy have stratum corneum abnormalities that distinguish them from other atopic dermatitis endotypes and children without atopic disease.
Children With Atopic Dermatitis Have Worse Sleep Quality
Children with atopic dermatitis were more likely to report worse sleep quality, with increased odds of experiencing more sleep-quality disturbances.
Dupilumab Approved to Treat Adolescents With Moderate-to-Severe Atopic Dermatitis
The FDA has approved Dupixant to treat moderate-to-severe atopic dermatitis in adolescent patients.
Gestational and Delivery Variables Linked With Dermatitis, Food Allergy Profiles
Gestational duration and Cesarean sections were associated with comorbid atopic dermatitis and food allergies in children, respectively.
Investigational Cream Promising for Atopic Dermatitis
In a phase 2b trial, success rates were higher with TRPV1 antagonist than with vehicle cream.
Increased Risk of Depression, Suicide in Atopic Dermatitis
The prevalence of depression in patients with atopic dermatitis was higher than in those without atopic dermatitis.
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