Tobacco Smoke Exposure Limits Benefits of CFTR Modulators in Cystic Fibrosis
Tobacco smoke exposure inhibited the therapeutic benefit of the cystic fibrosis transmembrane conductance regulator modulators in pediatric patients.
ATS 2020
Lower Calculated Lung Cancer Risk in Black Patients Eligible for Screening
Compared with white patients, black patients with screen-detected cancers had a lower calculated lung cancer risk, despite having a significantly higher mean 6-year lung cancer risk.
Prenatal Exposure to Household Air Pollution Affects Lung Development in Early Childhood
Prenatal and early life exposure to household air pollution may affect the development of lung function and lead to an increase in airway resistance in children.
Single-Inhaler Therapy vs Multiple-Inhaler Triple Therapy Outcomes in COPD
In patients with COPD, treatment with single-inhaler fluticasone furoate/umeclidinium/vilanterol resulted in more health status improvements and greater lung function benefit compared with multiple-inhaler triple therapy.
Electronic Communication From Pulmonologist to PCP Beneficial in COPD Care
Preemptive, patient-specific electronic messages from pulmonologists to primary care physicians improved guideline concordant care in COPD.
Safety and Efficacy of BAY 1817080 in Patients With Refractory Chronic Cough
BAY 1817080, a potent selective P2X3 receptor antagonist, may have utility as a new treatment for refractory chronic cough.
Current and Former Smokers With COPD Have Risk for Cognitive Impairment
Approximately 1 in 4 current and former smokers with chronic obstructive pulmonary disease are at risk for mild cognitive impairment and dementia.
Masitinib Significantly Reduced Exacerbations in Uncontrolled Severe Asthma
The first-in-class tyrosine kinase inhibitor masitinib decreased asthma exacerbations greater than placebo in patients with severe asthma uncontrolled by oral corticosteroids.
Inhaled Nitric Oxide at Higher Dose Improves Activity in PH Associated With ILD
Inhaled nitric oxide 45 mcg/kg of ideal body weight per hour was effective for improving physical activity in patients at risk for pulmonary hypertension associated with fibrotic interstitial lung disease.
Discontinuing Mepolizumab Decreases Asthma Control, Increases Eosinophil Counts
Patients with severe eosinophilic asthma who are treated with mepolizumab and subsequently stop treatment have increased blood eosinophil counts and increased exacerbations, among other negative clinical outcomes.
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