ACTIV-2 and Operation Warp Speed: An Interview With COVID-19 Investigator, Davey Smith, MD
Davey Smith, MD, provides insight into current and future research opportunities targeting SARS-CoV-2.
COVID19
NIH: Immune Modulators to Be Investigated for COVID-19
The NIH-led trial will assess 3 drugs: infliximab, a tumor necrosis factor blocker, abatacept, a selective T cell costimulation modulator, and cenicriviroc, an investigational immunomodulator that blocks 2 chemokine receptors, CCR2 and CCR5.
COVID-19 With COPD: Fewer Hospitalizations, But Greater Mortality
Chronic obstructive pulmonary disease may be associated with higher rates of mortality in patients with coronavirus disease 2019.
Using the MuLBSTA Score to Predict Mortality in COVID-19 Pneumonia
The MuLBSTA score accurately predicted outcomes of hospitalized patients with coronavirus disease 2019 (COVID-19) pneumonia.
Diabetes Increases Risk of In-Hospital Mortality in Patients With COVID-19
Hospitalized patients with severe COVID-19 and diabetes are less likely to be discharged from the hospital and are more likely to experience in-hospital mortality compared with patients without diabetes.
Pneumomediastinum May Increase Mortality in COVID-19 Pneumonia
Pneumomediastinum, although a rare phenomenon, is more prevalent in patients with COVID-19 compared with historical patients with adult respiratory distress syndrome.
Granulocytic Signature Predictive of COVID-19 Diagnosis and Severity
Researchers conducted an observational, prospective, multicentric study to assess the possible relationship between granulocytic markers and COVID-19 infection and severity.
Trial Evaluating Anti-SARS-CoV-2 Hyperimmune Globulin Begins
The antibody solution is derived from plasma donated by healthy individuals who have recovered from COVID-19.
Methyl-Prednisolone Pulses May Improve COVID-19 Pneumonia Prognosis
Patients with severe COVID-19 pneumonia had improved prognosis after receiving a short course of methyl-prednisolone pulses during the second week of disease.
How the Coronavirus Pandemic May Affect Cancer Clinical Trials
Risks of moving clinical trials online include missing key information about the patient experience — and higher dropout rates could also impair the overall quality of trials.
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