Brensocatib Proves Ineffective for Patients Hospitalized With COVID-19
A clinical trial in Britain explored whether treatment with brensocatib, a dipeptidyl peptidase-1 inhibitor, would improve COVID-19 outcomes.
Critical Care
D-Dimer Levels Have Limited Value in Identifying Pulmonary Embolism in COVID-19
Researchers explored the use of D-dimer levels to rule out PTE in patients with COVID-19, as well as clinical associations between D-dimer levels and PTE.
Hydroxychloroquine Does Not Prevent COVID-19 Infection in Patients With Rheumatic Diseases
Researchers assessed whether patients with rheumatic diseases receiving hydroxychloroquine therapy were at a lower risk for SARS-CoV-2 infection.
Helmet May Be Better Than Facemask in CPAP for COVID-19 Respiratory Failure
How does use of a helmet vs facemask for CPAP affect rates of survival and intubation in patients with acute hypoxemic respiratory failure due to COVID-19?
ACCP Updates Guideline for Perioperative Management of Antithrombotic Therapy
New topics in the ACCP guideline include the perioperative management of patients receiving direct oral anticoagulants and P2Y12 inhibitor antiplatelet drugs.
Can Pulmonary Embolism Severity Indices Predict COVID-19-Related Adverse Events?
Can the pulmonary embolism severity index assess the risk for adverse events among patients hospitalized for COVID-19 who are not diagnosed with PE or VTE?
Bronchoscopy Use Trends Among Patients Receiving Invasive Mechanical Ventilation
How often is bronchoscopy performed in patients on IMV due to acute respiratory failure — and how has this use of bronchoscopy changed over time?
How Does Obesity Affect Postoperative Tracheotomy Outcomes?
To what extent does obesity affect postoperative tracheotomy outcomes, such as length of hospital stay, duration of ventilation, and ventilator use at discharge?
Tracheostomy Linked to Lower Mortality in Patients With Severe COVID-19
Researchers assessed the clinical benefit of tracheostomy, which is often indicated for patients needing prolonged intubation, for patients with severe COVID-19.
Is a Multidisciplinary Difficult Airway Response Team Feasible and Effective?
The feasibility and effectiveness of the DART system, a multidisciplinary team-based approach to managing difficult airways, was assessed at a tertiary medical center.
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