Updated CHEST Guidelines on Antithrombotic Therapy in Venous Thromboembolism
The updated CHEST guideline on antithrombotic therapy for VTE includes 4 new PICO questions as well as updated recommendations based on newer evidence.
Critical Care
Effect of High-Dose Dexamethasone on Acute Respiratory Distress From COVID-19
Does high-dose dexamethasone increase the number of ventilator-free days among patients with COVID-19-related acute respiratory distress syndrome?
High vs Low Dose Dexamethasone for Severe COVID-19 Pneumonia
What dosage of dexamethasone most effectively improves outcomes in patients hospitalized with moderate or severe COVID-19 pneumonia?
Extracorporeal CO2 Removal: An alternative to intubation in AECOPD when NIV fails?
Is the use of extracorporeal CO2 removal (ECCO2R) a viable option for preventing intubation in patients with AECOPD for whom noninvasive ventilation failed?
Is Stroke-Associated Pneumonia Related to Transthyretin Levels?
Can development of stoke-associated pneumonia be predicted based on a patient’s 55-kDa protein transthyretin level?
Does Hypocalcemia Affect Mortality in Patients With Pulmonary Embolism?
Could calcium levels serve as a possible prognostic marker for in-hospital mortality among patients with pulmonary embolism?
Does Lenzilumab Improve Survival in Patients With COVID-19 Pneumonia?
A phase 3 clinical trial evaluated the monoclonal antibody lenzilumab for improving survival without mechanical ventilation in COVID-19 pneumonia.
Is Cytokine Blockade an Effective Therapeutic Strategy for COVID-19?
Can blockade of the interleukin-1 or IL-6 pathways shorten the time to clinical improvement in patients with COVID-19 or hypoxic respiratory failure?
Does Awake Prone Positioning Lower Risk of Intubation, Death in Severe COVID-19?
A meta-trial of 6 clinical trials evaluated the efficacy of awake prone positioning in preventing intubation and death in patients with severe COVID-19.
Therapeutic vs Prophylactic Heparin in Patients Hospitalized With Moderate COVID-19
Researchers conducted a study to compare the effects of therapeutic vs prophylactic heparin among patients hospitalized with moderate COVID-19.
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