Mortality among immunocompromised adult patients with acute respiratory failure requiring invasive mechanical ventilation was strongly associated with time to intubation.
The use of high-flow nasal oxygen vs helmet noninvasive ventilation did not significantly vary in terms of the number of days free from respiratory support in critically ill patients with severe hypoxemic respiratory failure from COVID-19.
Continuous regulation of cuff pressure of the tracheal tube using a pneumatic device was not superior to routine care in preventing ventilator-associated pneumonia in patients experiencing severe trauma.
Patients were randomized to receive either ruxolitinib 5mg twice daily (BID) plus standard of care (SoC), ruxolitinib 15mg BID plus SoC or placebo plus SoC.
The type and number of respiratory viruses in infants with severe bronchiolitis can predict the required duration of positive pressure ventilation use.
Five new recommendations were developed to reduce waste and enhance value in the practice of critical care.
Patient-directed prone positioning is not feasible in spontaneously breathing, nonintubated patients hospitalized with COVID-19.
In patients with septic shock, treatment with IV vitamin C, hydrocortisone, and thiamine does not lead to more rapid resolution compared with IV hydrocortisone alone.
Patients with ARDS who were placed in the prone position had improved gas exchange and reduced intensity of inspiratory effort compared with the supine position.
An existing virtual transition and recovery program for patients with sepsis may be used as a model for similar programs for COVID-19 survivors.
