Ibuprofen and Antibiotics Display Synergy Against Pseudomonas aeruginosa
Combinations of ibuprofen with aztreonam and ceftazidime display synergistic antimicrobial activity against drug-resistant Pseudomonas aeruginosa isolates in vitro.
Obstructive Lung Disease
Tezacaftor/Ivacaftor and Ivacaftor Approved for Younger Patients With Cystic Fibrosis
The FDA has approved Symdeko for the treatment of patients aged ≥6 years with cystic fibrosis.
Invasive Mechanical Ventilation May Improve Cystic Fibrosis Mortality Rates
Patients with cystic fibrosis who undergo invasive mechanical ventilation may have a lower risk for in-hospital mortality.
Bacterial Load: A Useful Marker of Antibiotic Response in Bronchiectasis
Bacterial load was a stable characteristic associated with worse quality of life and more airway inflammation in patients with bronchiectasis.
Poor Glucose Control Associated With Worse FEV1 Recovery Rates in CFRD
The investigators of this study sought to assess whether short-term glucose control affects FEV1 recovery during acute pulmonary exacerbation in patients with cystic fibrosis-related diabetes.
Final Height Impaired in Cystic Fibrosis After Rapid BMI Increase in Childhood
Final height was impaired in boys with cystic fibrosis who experienced a rapid increase in body mass index between the ages of 1 and 6.
Ivacaftor Approved for Cystic Fibrosis in Children as Young as 6 Months of Age
The FDA has expanded the indication for Kalydeco to include treatment of cystic fibrosis in patients 6 months of age and older.
Cystic Fibrosis May Progress Faster Due to Cytomegalovirus
Faster progression to end-stage lung disease observed in patients with cytomegalovirus immunoglobulin G positivity.
Effects of Azithromycin on Pulmonary Exacerbations in Pediatric Cystic Fibrosis
Approximately 70% azithromycin users with cystic fibrosis returned to ≥90% of baseline FEV1 compared with 61% of azithromycin nonusers.
Small-Molecule Ion Channels Restore Host Defenses in CF Airway Epithelia
Unselective small-molecule ion channels can restore host defenses in the airway epithelia of patients with cystic fibrosis.
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