Respiratory Microbiome Changes May Affect Airway Inflammation in Cystic Fibrosis
Lower microbial diversity in the respiratory tract in patients with cystic fibrosis was linked with prophylactic antibiotics and less airway inflammation.
Obstructive Lung Disease
Predicting Severity in Cystic Fibrosis With Sweat Chloride
Sweat chloride can predict severity in patients with CF, especially for long-term lung damage.
Lumacaftor/Ivacaftor Safe, Effective for Pediatric Cystic Fibrosis
Combination lumacaftor/ivacaftor therapy was found to be safe and effective in patients with cystic fibrosis aged 6 to 11 years.
Atorvastatin Improves Quality of Life in Patients With Bronchiectasis
Statin therapy reduces inflammation and improves quality of life in patients with severe bronchiectasis infected with P aeruginosa.
Efficacy of Home Noninvasive Ventilation With Oxygen Therapy in COPD, Hypercapnia
Patients with persistent hypercapnia following acute exacerbation of COPD, home noninvasive ventilation with home oxygen therapy prolonged readmission time.
Increase in Asthma and Allergy Symptoms Impacted by Climate Change
The rise in asthma and allergy symptoms may be due to climate change which heightens the damage of airway cells by outdoor fungus.
NIH: National Action Plan Unifies Approach to Ending US COPD Crisis
The release of a new autonomous approach for terminating the COPD crisis has been lead by the National Heart, Lung and Blood Institute (NHLBI).
Reducing Exacerbations in Moderate-to-Severe COPD With Beta-Blocker Therapy
Researchers examined the relationship between COPD and right and left ventricular morphometry to determine which patients may better respond to beta-blocker therapies.
FDA Expands Approved Use of Ivacaftor for Cystic Fibrosis
The FDA has expanded the approved indication of ivacaftor for cystic fibrosis, increasing the number of rare gene mutations the drug may be used to treat.
