Pitolisant Add-On CPAP Therapy Reduces Excessive Daytime Sleepiness in OSA
Pitolisant may be used as an add-on therapy to continuous positive airway pressure in patients with obstructive sleep apnea suffering from residual diurnal somnolence.
Obstructive Sleep Apnea
Inspire Therapy Approved for Younger Patients With Obstructive Sleep Apnea
The FDA has expanded the approval of Inspire therapy to include patients aged 18 to 21 years with moderate to severe OSA who are unable to use CPAP.
Convolution Neural Network Deep Learning Model Predicts Sleep Disorder in Asthma
Of the various deep learning approaches tested, the convolution neural network model showed the best ability to predict sleep disorder in a cohort of individuals with asthma.
Physiologic Traits Associated CPAP Adherence in Patients With Stroke and OSA
Physiologic traits that cause obstructive sleep apnea are also associated with adherence to continuous positive airway pressure in patients with stroke.
SNORE Utility Index Validated as Novel Sleep Apnea-Specific QoL Instrument
Researchers have developed and validated the SNORE (Symptoms of Nocturnal Obstruction and Related Events) Utility Index, a novel utility scoring algorithm, for use as a sleep apnea-specific quality-of-life instrument.
Atomoxetine Plus Oxybutynin Improves Multiple Variables in Obstructive Sleep Apnea
Atomoxetine plus oxybutynin demonstrated efficacy in improving upper airway collapsibility, increasing breathing stability, and reducing the threshold for arousal in obstructive sleep apnea.
The Bidirectional Nature of Asthma and Obstructive Sleep Apnea
Obstructive sleep apnea was positively associated with worse outcomes in patients hospitalized because of asthma exacerbations, including increased costs, longer lengths of stay, and the need for invasive respiratory therapy.
Risk Factors Associated With Cardiometabolic Comorbidities in Obstructive Sleep Apnea
Patients with obstructive sleep apnea who experience longer sleep apneas and hypopneas, worse sleep quality, and marked intermittent/global nocturnal hypoxemia are more at risk for cardiometabolic comorbidities.
Pitolisant Reduces Daytime Sleepiness in Patients Nonadherent to CPAP
In patients with obstructive sleep apnea who refuse or are nonadherent to continuous positive airway pressure therapy, pitolisant may reduce self-reported excessive daytime sleepiness.
Sleep Quality Related to Asthma Control and Severity
A significant correlation was seen between quality of sleep and asthma control.
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