Cefiderocol Approved for Hospital-Acquired, Ventilator-Associated Bacterial Pneumonia
The FDA has approved Fetroja® (cefiderocol; Shionogi) for the treatment of adult patients with HABP/VABP caused by susceptible Gram-negative pathogens.
Pneumonia
Hydrocortisone Did Not Reduce Mortality, Respiratory Support Need in COVID-19
Low-dose hydrocortisone was not associated with a significant reduction in death by day 21 of treatment compared with placebo in critically ill patients with COVID-19.
The Role of Artificial Intelligence in Pulmonary Imaging: Clinician Interview
Artificial intelligence has the potential to ease the workload of physicians while increasing the speed and accuracy of diagnosis, particularly in pulmonology.
ICD-9 Diagnosis Codes May Not Accurately Capture Pneumonia Etiology
ICD-9 organism-specific administrative codes for pneumonia appear to underestimate the prevalence of specific disease-associated pathogens in hospitalized patients.
Assessing Prone and Lateral Positioning in COVID-19 With Hypoxemic Respiratory Failure
Patients with hypoxemic acute respiratory failure because of COVID-19 who received CPAP therapy had a high failure rate during prone/lateral positioning tests.
No Benefit With Tocilizumab in COVID-19 Pneumonia Trial
A phase 3 study of tocilizumab for the treatment of hospitalized patients with severe COVID-19 pneumonia did not meet its primary and key secondary end points.
Ventilator-Associated Pneumonia in Traumatic Brain Injury: Incidence and Mortality
Ventilator-associated pneumonia occurs less often than previously described in intubated patients following traumatic brain injury, and it does not appear to have a worsening effect on neurologic outcomes and mortality.
NSAID Use Not Associated With Increased Death, ICU Admission in Influenza
Patients who were hospitalized with influenza who were taking a NSAID medication had no increased risk of intensive care unit admission or death.
Mavrilimumab Improves Clinical Outcomes in Severe COVID-19 Pneumonia
Treatment with mavrilimumab is associated with improved clinical outcomes compared with standard care in non-mechanically ventilated patients with severe COVID-19 pneumonia and systemic hyperinflammation.
Pneumocystis Pneumonia Associated With Higher Mortality in Lung Transplants
Patients receiving lung transplants who had pneumocystis pneumonia had higher mortality rates than those without pneumocystis pneumonia.
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