FDA: Tuberculosis Drugs May Contain Nitrosamine Impurities
Currently, there is no available evidence to assess the carcinogenic potential of MNP and CPNP.
Tuberculosis
Vitamin D Supplementation Does Not Lower Risk for Primary Tuberculosis Infection
A team of investigators conducted a phase 3, double-blind trial to assess the impact of vitamin D supplementation on risk of tuberculosis infection in public schoolchildren in Mongolia.
Comparison Finds Rifampin Superior in Cost, Safety to Isoniazid for Latent Tuberculosis
A shorter regimen of rifampin is safer and less expensive than the standard 9-month regimen of isoniazid for treatment latent tuberculosis.
Effect of COVID-19 Estimated on Tuberculosis, HIV, and Malaria Services
The greatest effect on tuberculosis would be from a reduction in timely diagnosis and treatment of new cases, resulting from prolonged COVID-19 suppression interventions.
Costs Associated With 4 Months of Rifampin vs 9 Months of Isoniazid in Latent TB
Health system use and costs higher for 9 months of isoniazid vs 4 months of rifampin in adults and children in all settings.
Unsuccessful Treatment Outcomes in Nontuberculosis Mycobacteria Lung Disease
Approximately one-third of adults who undergo treatment for nontuberculosis mycobacteria lung disease experience an unsuccessful outcome, with adverse events and treatment discontinuation being major challenges.
Tuberculosis Alone and With HIV Co-Infection: Treatment Updates
In a general population of patients with latent TB infection (including patients with and without HIV), studies have confirmed the superior safety profile of treatment with rifampicin vs isoniazid.
QuantiFERON-TB Gold Plus Comparable to Other Assays for Incident Tuberculosis
QuantiFERON-TB Gold Plus was comparable to other interferon gamma release assays for predicting tuberculosis in adults with recent contacts.
Incidence of Tuberculosis High in Children Exposed to the Disease
Preventive therapy was effective in most children with tuberculosis if given before development of active disease.
Survey: Management of Amikacin Liposome Inhalation Suspension-Associated Respiratory Adverse Events
Findings from patient-directed survey showed that the most commonly reported respiratory adverse events included dysphonia, increased sputum production, increased cough and dyspnea.
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