Predicting COPD Exacerbations, Treatment Responses via Eosinophil Counts

Predicting COPD Exacerbations, Treatment Responses via Eosinophil Counts

COPD exacerbation risk and treatment response may be predicted using blood eosinophil counts.

Procalcitonin-Guided Pneumonia Treatment Associated With Improved Outcomes

Procalcitonin-Guided Pneumonia Treatment Associated With Improved Outcomes

Procalcitonin may decrease mortality rates in patients with acute respiratory infections, including pneumonia.

Childhood Wheezing Illness Risk Modified by Lactobacillus Microbiome in RSV

Childhood Wheezing Illness Risk Modified by Lactobacillus Microbiome in RSV

Nasopharyngeal detection and increased abundance of Lactobacillus during acute respiratory infection with respiratory syncytial virus was associated with a lower risk for childhood wheezing illnesses.

COPD Continues to Present Screening Challenges, Research Barriers

COPD Continues to Present Screening Challenges, Research Barriers

No data have demonstrated improved mortality, morbidity, or quality of life as a result of screening for COPD in asymptomatic individuals.

Cardiopulmonary Bypass: First-Ever Anticoagulation Guidelines Released

Cardiopulmonary Bypass: First-Ever Anticoagulation Guidelines Released

Clinical practice guidelines for anticoagulation therapy for cardiopulmonary bypass has been released.

Bronchopulmonary Dysplasia Prevention in Preterm Infants

Bronchopulmonary Dysplasia Prevention in Preterm Infants

Budesonide may lower the rates of bronchopulmonary dysplasia in preterm infants.

Enteral vs Parenteral Nutrition in Critical Care Requiring Mechanical Ventilation

Enteral vs Parenteral Nutrition in Critical Care Requiring Mechanical Ventilation

Enteral nutritional support was not clinically superior to parenteral nutritional support in critically ill patients receiving mechanical ventilation.

Evidence for Immunotherapy in Pediatric Asthma Lacking

Evidence for Immunotherapy in Pediatric Asthma Lacking

Children with allergic asthma do not significantly benefit from subcutaneous or sublingual immunotherapy.

Nebulized Hypertonic Saline vs Normal Saline in Infants With Acute Bronchiolitis

Nebulized Hypertonic Saline vs Normal Saline in Infants With Acute Bronchiolitis

Nebulized hypertonic saline may decrease length of hospital stay and improve clinical severity scores in infants with acute bronchiolitis.

School-based telemedicine enhances asthma management in children

A school-based telemedicine program with directly observed preventive therapy, when compared to enhanced usual care, led to more symptom-free days and fewer emergency department visits or hospitalizations.

Preventing COPD Exacerbations in Upper Respiratory Tract Infections

Preventing COPD Exacerbations in Upper Respiratory Tract Infections

A significant reduction in severe COPD exacerbations was seen with intensified combination therapy at the onset of upper respiratory tract infections.

Tuberculosis Risk in Type 2 Diabetes Medications

Tuberculosis Risk in Type 2 Diabetes Medications

Patients with type 2 diabetes treated with sulfonylureas had a higher risk of contracting tuberculosis compared with metformin.

COPD Home-Based Coaching Intervention: Effects on Physical Activity, Healthcare Utilization

COPD Home-Based Coaching Intervention: Effects on Physical Activity, Healthcare Utilization

Patients with COPD may increase their physical activity levels using a home-based coaching intervention.

Stable Hypercapnic COPD May Benefit From At-Home High-Flow Nasal Cannula Oxygen Therapy

Stable Hypercapnic COPD May Benefit From At-Home High-Flow Nasal Cannula Oxygen Therapy

Patients with stable hypercapnic COPD reported improved health-related quality of life after 6 weeks of at-home high-flow nasal cannula oxygen therapy.

Effect of Corticosteroids on Pneumonia-Related Mortality

Effect of Corticosteroids on Pneumonia-Related Mortality

Mortality from severe pneumonia may be significantly reduced with corticosteroids.

Inhaled Long-Acting Bronchodilators for COPD: Potential Cardiovascular Risk

Inhaled Long-Acting Bronchodilators for COPD: Potential Cardiovascular Risk

Within the first 30 days of therapy, patients with COPD who began using long-acting bronchodilators had a 1.5-fold increased risk for cardiovascular events.

Overcoming Challenges to Create a Universal Influenza Vaccine

Overcoming Challenges to Create a Universal Influenza Vaccine

Researchers from the National Institute of Allergy and Infectious Diseases are working to develop a universal influenza vaccine.

Intravenous Antibiotic Recalled Due to Mold

Intravenous Antibiotic Recalled Due to Mold

AuroMedics Pharma announced a voluntary recall of 1 lot of Linezolid injection after a batch found contained mold.

Improving Prognosis in Idiopathic Pulmonary Fibrosis-Associated Pulmonary Hypertension

Improving Prognosis in Idiopathic Pulmonary Fibrosis-Associated Pulmonary Hypertension

Bosentan may benefit a subset of patients with idiopathic pulmonary fibrosis-associated pulmonary hypertension.

New Trial to Assess Dabigatran in Intermediate-Risk Pulmonary Embolism

New Trial to Assess Dabigatran in Intermediate-Risk Pulmonary Embolism

A clinical trial is underway to assess the safety and efficacy of dabigatran in intermediate-risk pulmonary embolism after completing 72 hours of heparin therapy.

Tuberculosis Screening: Updated Recommendations from CHEST

Tuberculosis Screening: Updated Recommendations from CHEST

New recommendations suggest that high risk tuberculosis patients with cough should be screened for pulmonary tuberculosis.

Efficacy and Safety of Benralizumab in Adults With Eosinophilic Asthma

Efficacy and Safety of Benralizumab in Adults With Eosinophilic Asthma

Asthma exacerbations may be reduced in patients with eosinophilic asthma treated with benralizumab.

Effect of Beta-Blockers on Hospitalization in COPD and Concurrent Heart Failure

Effect of Beta-Blockers on Hospitalization in COPD and Concurrent Heart Failure

Carvedilol may increase the risk for hospitalization in patients with concurrent heart failure and COPD compared with metoprolol/bisoprolol/nebivolol.

Thromboembolic Event Risk With Cisplatin vs Carboplatin in Lung Cancer

Thromboembolic Event Risk With Cisplatin vs Carboplatin in Lung Cancer

Platinum-based chemotherapy agents for lung cancer may increase the risk for thromboembolism.

New Influenza Vaccine Guidelines Released for Patients With Egg Allergy

New Influenza Vaccine Guidelines Released for Patients With Egg Allergy

Patients with an egg allergy do not need to avoid or take special precautions when receiving the influenza vaccine.

Homeopathic Products Will Undergo New FDA Regulations

Homeopathic Products Will Undergo New FDA Regulations

The FDA announced a new enforcement strategy to regulate drug products labeled as homeopathic.

Acute Respiratory Tract Infections in Children: Broad- vs Narrow-Spectrum Antibiotics

Acute Respiratory Tract Infections in Children: Broad- vs Narrow-Spectrum Antibiotics

Broad-spectrum antibiotics are not associated with better clinical or patient-centered outcomes in children with acute respiratory tract infections.

Comparing Treatments for Acute Respiratory Distress Syndrome

Comparing Treatments for Acute Respiratory Distress Syndrome

In patients with acute respiratory distress syndrome, cisatracurium does not improve mortality when compared with vecuronium, but is associated with improvements in other outcomes.

FDA Approves Removal of Box Warning From Advair, Breo Asthma Therapies

FDA Approves Removal of Box Warning From Advair, Breo Asthma Therapies

Updates were also made to the Warnings and Precautions section of labeling for ICS/LABA-class medications.

Precision Medicine May Pave the Way for Better Treatment in Asthma, COPD

Precision Medicine May Pave the Way for Better Treatment in Asthma, COPD

At a research seminar held by the European Respiratory Society in February 2017, a group of investigators discussed how precision medicine may improve treatment in asthma and COPD.

Maintaining Asthma Control With Reduced Daily Inhaled Corticosteroid Dose

Maintaining Asthma Control With Reduced Daily Inhaled Corticosteroid Dose

Daily inhaled corticosteroid dose can be safely reduced in some adult patients with asthma.

Physiotherapy Breathing Retraining Improves Quality of Life in Uncontrolled Asthma

Physiotherapy Breathing Retraining Improves Quality of Life in Uncontrolled Asthma

Nonpharmacological approaches to asthma management may improve patient quality of life.

Pharmacist Presence in Medical Home Practices May Improve Patient Outcomes

Pharmacist Presence in Medical Home Practices May Improve Patient Outcomes

Integrating clinical pharmacists into primary care medical home practices helps patients achieve better disease management for high blood pressure and diabetes mellitus.

Short-Duration Dexamethasone Effective for Pediatric Asthma Exacerbations

Short-Duration Dexamethasone Effective for Pediatric Asthma Exacerbations

Children with asthma exacerbations may be treated with 2 doses of dexamethasone instead of with prednisolone/prednisone.

Nasal High-Flow Oxygen Corrects Hypoxemia, Reduces Hypercapnia in COPD

Nasal High-Flow Oxygen Corrects Hypoxemia, Reduces Hypercapnia in COPD

Nasal high-flow oxygen therapy may be a safe and effective therapy for patients with normocapnic and hypercapnic COPD.

Apnea/Hypopnea Index in OSA Improves With Dronabinol

Apnea/Hypopnea Index in OSA Improves With Dronabinol

Dronabinol may be an effective treatment in adults with obstructive sleep apnea.

FDA Approves First Treatment for Eosinophilic Granulomatosis With Polyangiitis

FDA Approves First Treatment for Eosinophilic Granulomatosis With Polyangiitis

Prior to this expanded indication, patients with this challenging, rare disease did not have an FDA-approved treatment option.

Chronic Lung Disease Research in the Pipeline: An Interview With Augustine M.K. Choi, MD

Chronic Lung Disease Research in the Pipeline: An Interview With Augustine M.K. Choi, MD

Pulmonology Advisor sits down with Augustine M.K. Choi, MD, Stephen and Suzanne Weiss Dean of Weill Cornell Medicine to discuss the latest topics in pulmonary medicine.

Examining the Efficacy of Carbon Monoxide Therapy in Idiopathic Pulmonary Fibrosis: An Interview With Augustine M.K. Choi, MD

Examining the Efficacy of Carbon Monoxide Therapy in Idiopathic Pulmonary Fibrosis: An Interview With Augustine M.K. Choi, MD

Pulmonology Advisor sits down with Augustine M.K. Choi, MD, Stephen and Suzanne Weiss Dean of Weill Cornell Medicine to discuss the latest topics in pulmonary medicine.

Pulmonary Emboli in Pediatric Patients: Clinical Predictors Identified

Pulmonary Emboli in Pediatric Patients: Clinical Predictors Identified

Prospective validation research is needed before these clinical predictors of pediatric PE can become guidelines.

Outcomes With Catheter-Directed vs Systemic Thrombolysis in Intermediate-Risk Pulmonary Emboli

Outcomes With Catheter-Directed vs Systemic Thrombolysis in Intermediate-Risk Pulmonary Emboli

A systematic review evaluated whether catheter-directed thrombolysis improved outcomes in patients with intermediate-risk pulmonary emboli.

Veno-Arterial Extracorporeal Membrane Oxygenation Effective for Massive PE

Veno-Arterial Extracorporeal Membrane Oxygenation Effective for Massive PE

The use of veno-arterial extracorporeal membrane oxygenation as bridge therapy for massive pulmonary embolism may allow clinicians to better triage patients to appropriate destination therapy.

Identifying New Therapeutics for Pulmonary Diseases: An Interview With Augustine M.K. Choi, MD

Identifying New Therapeutics for Pulmonary Diseases: An Interview With Augustine M.K. Choi, MD

Pulmonology Advisor sits down with Augustine M.K. Choi, MD of Stephen and Suzanne Weiss Dean of Weill Cornell Medicine to discuss the latest topics in pulmonary medicine.

Overview of Autophagy Research in COPD: An Interview With Augustine M.K. Choi, MD

Overview of Autophagy Research in COPD: An Interview With Augustine M.K. Choi, MD

Pulmonology Advisor sits down with Augustine M.K. Choi, MD, Stephen and Suzanne Weiss Dean of Weill Cornell Medicine to discuss the latest topics in pulmonary medicine.

FDA Approves First Nebulized Long-Acting Muscarinic Antagonist for COPD

FDA Approves First Nebulized Long-Acting Muscarinic Antagonist for COPD

Adults treated with Lonhala Magnair showed statistically significant and clinically important changes in FEV1 at week 12 vs placebo.

COPD Adverse Outcomes May Increase With Loop Diuretic Use

COPD Adverse Outcomes May Increase With Loop Diuretic Use

Older patients with COPD who use loop diuretics may be at an increased risk for respiratory-related morbidity and mortality.

HIV Viral Loads May Affect Echocardiographic Pulmonary Pressure

HIV Viral Loads May Affect Echocardiographic Pulmonary Pressure

Individuals who are HIV-positive may be at a higher risk for increased pulmonary pressure and mortality.

Examining Compression-to-Ventilation Ratios for Optimal Neurologic, Survival Outcomes

Examining Compression-to-Ventilation Ratios for Optimal Neurologic, Survival Outcomes

Adults with cardiac arrest have better outcomes with continuous compressions with asynchronous ventilations or compression-to-ventilation ratios of 30:2.

Anticoagulation Therapy Often Poorly Managed in Pulmonary Arterial Hypertension

Anticoagulation Therapy Often Poorly Managed in Pulmonary Arterial Hypertension

A study evaluated the quality of targeted anticoagulation in patients with PAH, and examined outcomes associated with poor time spent within targeted anticoagulation range.

Pneumonia Found Infrequently on Chest X-Ray in Children With Acute Asthma Exacerbations

Pneumonia Found Infrequently on Chest X-Ray in Children With Acute Asthma Exacerbations

Chest radiography, a procedure often performed in the emergency department, infrequently changes medical management of children with acute asthma exacerbations.

Asthma Control in Nonobese Patients Improves With Exercise and Diet

Asthma Control in Nonobese Patients Improves With Exercise and Diet

Exercise and diet improves asthma control in nonobese patients with asthma.

Lung Transplantation for Pulmonary Arterial Hypertension: Overview and Bridging Therapies

Lung Transplantation for Pulmonary Arterial Hypertension: Overview and Bridging Therapies

Lung transplantation may be an option in patients with severe pulmonary arterial hypertension who do not respond well to medical therapy.

Riociguat Studied in Pediatric Patient With Pulmonary Arterial Hypertension

Riociguat Studied in Pediatric Patient With Pulmonary Arterial Hypertension

Select pediatric patients with pulmonary arterial hypertension may benefit from treatment with riociguat.

Children's Behavior During Inhalation Induction May Affect Sevoflurane Concentrations

Children's Behavior During Inhalation Induction May Affect Sevoflurane Concentrations

Higher sevoflurane concentrations in the anesthesiologist's breathing zone is tied to negative behavior in children having elective ear, nose & throat surgery.

Bronchiolitis Treatment in Infants Varies by Hospital

Bronchiolitis Treatment in Infants Varies by Hospital

The use of evidence-based supportive therapies varies by hospital site for infants with bronchiolitis,

Intranasal Omalizumab Use and Systemic Total Immunoglobulin E Levels

Intranasal Omalizumab Use and Systemic Total Immunoglobulin E Levels

Intranasal administration of omalizumab does not result in relevant change of allergen-specific and total IgE levels in patients with birch pollen allergy.

Unnecessary Antibiotic Prescribing Continues in Young Adults With Acute Bronchitis

Unnecessary Antibiotic Prescribing Continues in Young Adults With Acute Bronchitis

Overprescription for uncomplicated acute bronchitis is common despite guidelines recommending against it.

Allergy Nasal Spray FlutiCare OTC Now Available

Allergy Nasal Spray FlutiCare OTC Now Available

FlutiCare OTC can relieve both indoor and outdoor allergy symptoms caused by pollen, dust, and animal dander.

Cancer-Related Fatigue May Benefit From Acupuncture

Cancer-Related Fatigue May Benefit From Acupuncture

More than 50% of patients report experiencing cancer-related fatigue throughout the disease process.

Omalizumab May Be Stepped-Down or Withdrawn in Severe Allergic Asthma

Omalizumab May Be Stepped-Down or Withdrawn in Severe Allergic Asthma

Omalizumab may be safely withdrawn or stepped down in patients with severe allergic asthma.

Inhaled Corticosteroid Use and Fracture Risk in Pediatric Asthma

Inhaled Corticosteroid Use and Fracture Risk in Pediatric Asthma

A population-based study aimed to determine whether inhaled corticosteroid use increased risk of fracture in children with asthma.

Liquid Biopsy May Be a Noninvasive Measure for Treatment Response in NSCLC

Liquid Biopsy May Be a Noninvasive Measure for Treatment Response in NSCLC

Patients with PD-L1-positive malignancies have shown higher response rates to immune checkpoint inhibition and consequently prolonged progression-free/overall survival compared with others.

CFTR Modulator Therapy With Tezacaftor-Ivacaftor in Cystic Fibrosis

CFTR Modulator Therapy With Tezacaftor-Ivacaftor in Cystic Fibrosis

Effective cystic fibrosis transmembrane conductance regulator modulator therapy may be of benefit in subsets of patients with cystic fibrosis.

Noninvasive Ventilation for Acute Hypercapnic Respiratory Failure Related to COPD

Noninvasive Ventilation for Acute Hypercapnic Respiratory Failure Related to COPD

Noninvasive ventilation may reduce mortality in patients with acute hypercapnic respiratory failure related to COPD.

Antipyretic Effect on Immune Response to Flu Vaccination in Young Children

Antipyretic Effect on Immune Response to Flu Vaccination in Young Children

Antipyretic administration for fever in young children is not associated with any significant blunting of immune response to inactivated influenza vaccination.

Asthma Clinical Trials Need to Include Patient-Reported Outcomes

Asthma Clinical Trials Need to Include Patient-Reported Outcomes

More asthma clinical trials will include patient-reported outcomes as they will help guide clinicians' understanding of their patients' disease.

ACAAI Releases Updated Allergic Rhinitis Treatment Guidelines

ACAAI Releases Updated Allergic Rhinitis Treatment Guidelines

The American College of Allergy, Asthma, and Immunology has issued updated guidelines on seasonal allergic rhinitis treatment.

Pulmonary Arterial Hypertension: Using Biomarkers to Assess Treatment Response

Pulmonary Arterial Hypertension: Using Biomarkers to Assess Treatment Response

Using biomarkers in pulmonary arterial hypertension may be a less invasive strategy for assessing response to treatment.

Benralizumab Approved by FDA for Severe Eosinophilic Asthma

Benralizumab Approved by FDA for Severe Eosinophilic Asthma

A significant improvement in lung function and annual asthma exacerbation rate was noted vs placebo.

Non-Small Cell Lung Cancer: Nivolumab vs Docetaxel for Long-Term Efficacy

Non-Small Cell Lung Cancer: Nivolumab vs Docetaxel for Long-Term Efficacy

Results of two phase 3 studies found that nivolumab provided superior overall survival vs docetaxel in people with non-small cell lung cancer.

Severe Steroid-Dependent Asthma Benefits From Dupilumab

Severe Steroid-Dependent Asthma Benefits From Dupilumab

Patients treated with dupilumab experienced fewer asthma exacerbations than the overall population.

Asthma Control With Mobile Health Initiatives

Asthma Control With Mobile Health Initiatives

Mobile devices may help patients with asthma better manage and control their disease.

Asthma Exacerbations Treated With Injectable Dexamethasone Administered Orally

Asthma Exacerbations Treated With Injectable Dexamethasone Administered Orally

Pediatric patients benefited from orally administered injectable dexamethasone for asthma exacerbations.

Internet-Based Survey Identifies Patients With Labile Asthma Control

Internet-Based Survey Identifies Patients With Labile Asthma Control

A survey that was part of the Severe Asthma Research Program found a specific subgroup of patients with asthma who have highly variable asthma control.

CPAP vs Laparoscopic Gastric Banding Surgery for Obstructive Sleep Apnea

CPAP vs Laparoscopic Gastric Banding Surgery for Obstructive Sleep Apnea

Bariatric surgery and continuous positive airway pressure were directly compared as initial treatment modalities for obstructive sleep apnea.

Anti-Inflammatory Therapy With Canakinumab May Reduce Lung Cancer Rates

Anti-Inflammatory Therapy With Canakinumab May Reduce Lung Cancer Rates

Patients with lung cancer and atherosclerosis diagnosis may benefit from anti-inflammatory therapy with canakinumab.

Treatment Completion for Latent Tuberculosis

Treatment Completion for Latent Tuberculosis

Self-administered TB therapy should be considered when directly observed therapy is not feasible.

Quality of Life Benefits of Yoga in Non-Small Cell Lung Cancer

Quality of Life Benefits of Yoga in Non-Small Cell Lung Cancer

Patients with NSCLC experienced improvements in both function and quality of life with yoga therapy.

Montelukast Reduces Need for Rescue Medication in Young Children

Montelukast Reduces Need for Rescue Medication in Young Children

Montelukast therapy reduced the need for rescue medication in young children with recurring wheezing illness.

Use of Antibiotic Prophylaxis in Young Children With Cystic Fibrosis

Use of Antibiotic Prophylaxis in Young Children With Cystic Fibrosis

In children with cystic fibrosis, risk for first detection of S aureus and P aeruginosa was greater in those who had received antibiotic prophylaxis.

Long-Term Inhaled Corticosteroid Use Associated With Increased Sputum Bacterial Load in COPD

Long-Term Inhaled Corticosteroid Use Associated With Increased Sputum Bacterial Load in COPD

Salmeterol plus fluticasone was associated with a significant increase in sputum bacterial load in chronic obstructive pulmonary disease, compared to salmeterol alone.

Telemedicine Effective for Allergy Management

Telemedicine Effective for Allergy Management

Further research is needed, but the position statement authors support the use of telemedicine as a method of health care delivery.

Lung Recruitment Maneuver With Titrated PEEP Increases Mortality in Moderate to Severe ARDS

Lung Recruitment Maneuver With Titrated PEEP Increases Mortality in Moderate to Severe ARDS

A randomized trial sought to determine whether the use of titrated positive end-expiratory pressure influenced the 28-day mortality risk in patients with acute respiratory distress syndrome.

Redesigned Inhalation Device for PAH Approved by FDA

Redesigned Inhalation Device for PAH Approved by FDA

The new device features a more ergonomic design with a single-button operation, an intuitive user interface to adjust breath counts, a rechargeable battery, and a display that guides patients through the inhalation process.

Updated Lung Cancer Screening Guidelines Released at CHEST

Updated Lung Cancer Screening Guidelines Released at CHEST

The ACCP just released new lung cancer screening guidelines.

Pulmonary Edema After Prostacyclin Therapy for PAH Associated With Worse Outcomes

Pulmonary Edema After Prostacyclin Therapy for PAH Associated With Worse Outcomes

Patients who develop pulmonary edema after starting prostacyclin for pulmonary arterial hypertension have a greater risk for mortality.

Asthma Management During Pregnancy: How to Benefit Both Mothers and Infants

Asthma Management During Pregnancy: How to Benefit Both Mothers and Infants

Although some pregnant women discontinue their asthma medications for fear of fetal drug toxicity, they may be putting their babies at greater risk.

Once- vs Twice-Daily Treatment for Controlled Asthma: Examining Outcomes

Once- vs Twice-Daily Treatment for Controlled Asthma: Examining Outcomes

Researchers assessed the efficacy of a once-daily treatment option for controlled asthma.

Beta Blockers Linked to Longer Life Expectancy in COPD

Beta Blockers Linked to Longer Life Expectancy in COPD

In a retrospective analysis, researchers examined the efficacy of beta blocker therapy in prolonging patients' lives.

COPD: Concurrent Nebulized Glycopyrrolate, Long-Acting Bronchodilators Safe

COPD: Concurrent Nebulized Glycopyrrolate, Long-Acting Bronchodilators Safe

The safety of concurrently administering nebulized glycopyrrolate with long-acting beta agonists was examined in 3 studies.

Asthma Exacerbations May Be Alleviated With Vitamin D Supplementation

Asthma Exacerbations May Be Alleviated With Vitamin D Supplementation

Asthma exacerbations may be reduced with vitamin D supplementation.

Mesothelioma Progression-Free Survival Does Not Improve With Anetumab Ravtansine

Mesothelioma Progression-Free Survival Does Not Improve With Anetumab Ravtansine

Median overall survival increased from 10.1 months with anetumab ravtansine to 11.6 months with vinorelbine.

Peramivir Injection Now Available for Acute Uncomplicated Influenza in Children

Peramivir Injection Now Available for Acute Uncomplicated Influenza in Children

Rapivab is now indicated for use in pediatric patients ≥2 years with acute uncomplicated influenza.

Home Sleep Apnea Testing: American Academy of Sleep Medicine Position Statement

Home Sleep Apnea Testing: American Academy of Sleep Medicine Position Statement

Home sleep apnea tests are a less expensive alternative to polysomnography tests in detecting obstructive sleep apnea.

Small-cell Lung Cancer Benefits From Maintenance Therapy With Pazopanib

Small-cell Lung Cancer Benefits From Maintenance Therapy With Pazopanib

Pazopanib improves progression-free survival in patients with small-cell lung cancer.

Gefitinib Treatment Should Be Avoided Prior to Chemotherapy in Non-small Cell Lung Cancer

Gefitinib Treatment Should Be Avoided Prior to Chemotherapy in Non-small Cell Lung Cancer

First generation EGFR tyrosine kinase inhibitors should be used in combination with chemotherapy if a patient has progressive EGFR mutation-positive non-small cell lung cancer.

Nebulized Antibiotics May Prevent Ventilator-Associated Pneumonia Occurrence

Nebulized Antibiotics May Prevent Ventilator-Associated Pneumonia Occurrence

Prophylactic antibiotics administered to patients who were mechanically ventilated reduced the rate of ventilator-associated pneumonia.

Inhaled Corticosteroids Do Not Increase Risk for Pneumonia in COPD

Inhaled Corticosteroids Do Not Increase Risk for Pneumonia in COPD

In contrast to previous study findings, inhaled corticosteroids do not appear to increase risk for pneumonia in patients with COPD with moderate airflow limitation.

Dacomitinib vs Gefitinib for Progression-Free Survival in Non-small Cell Lung Cancer

Dacomitinib vs Gefitinib for Progression-Free Survival in Non-small Cell Lung Cancer

Dacomitinib improved progression-free survival in patients with non-small cell lung cancer.

Empiric Antibiotic Therapy in Hospital-Acquired and Ventilator-Associated Pneumonia

Empiric Antibiotic Therapy in Hospital-Acquired and Ventilator-Associated Pneumonia

Strictly following empirical antimicrobial treatment guidelines in patients with hospital-acquired or ventilator-associated pneumonia may result in overtreatment with antibiotics.

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