Case Report: Serious Skin Rash With Sleep Disorder Tx

Case Report: Serious Skin Rash With Sleep Disorder Tx

A patient developed Stevens-Johnson Syndrome following armodafinil therapy for daytime sleepiness.

How Does CVD Comorbidity Influence Bronchodilator Tx in COPD?

How Does CVD Comorbidity Influence Bronchodilator Tx in COPD?

Associated cardiovascular side effects of bronchodilators may reduce prescription rates in patients with COPD with comorbid cardiovascular disease.

Efficacy of Home Noninvasive Ventilation With Oxygen Therapy in COPD, Hypercapnia

Efficacy of Home Noninvasive Ventilation With Oxygen Therapy in COPD, Hypercapnia

Patients with persistent hypercapnia following acute exacerbation of COPD, home noninvasive ventilation with home oxygen therapy prolonged readmission time.

ACEi, ARB Use Improves Pulmonary Function in Emphysema

ACEi, ARB Use Improves Pulmonary Function in Emphysema

Higher doses were independently linked to slower change in emphysema, especially among former smokers

Can Angiotensin II Improve BP in Patients With Vasodilatory Shock?

Can Angiotensin II Improve BP in Patients With Vasodilatory Shock?

Angiotensin II decreased the requirement to use catecholamines in patients with vasodilatory shock.

Maintenance Therapy With Tiotropium Bronchodilator in Uncontrolled Asthma

Maintenance Therapy With Tiotropium Bronchodilator in Uncontrolled Asthma

Two phase 3 clinical development programs showed improved breathing in children and adolescents with moderate-to-severe asthma regardless of allergic status.

Vaccine Therapies Show Promise As Lung Cancer Tx

Vaccine Therapies Show Promise As Lung Cancer Tx

Developed in Cuba, the TG4010 and CIMAvax-EGF vaccines are undergoing clinical study in the US.

Cannabinoids: A Potential Therapy for Obstructive Sleep Apnea

Cannabinoids: A Potential Therapy for Obstructive Sleep Apnea

Research presented at SLEEP 2017 suggests that dronabinol, previously used to treat chemotherapy-induced nausea and vomiting, may be an effective treatment for sleep apnea.

Lung Transplant Tx Linked to Squamous Cell Carcinoma Recurrence

Lung Transplant Tx Linked to Squamous Cell Carcinoma Recurrence

A retrospective cohort study examined squamous cell carcinoma outcomes in adult lung transplant recipients who received voriconazole.

Recall: NasalCrom Allergy Spray

Recall: NasalCrom Allergy Spray

NasalCom nasal spray has been recalled due to possible microbial contamination in the water used to manufacture the product.

ACE Inhibitors, ARBs Slow Progression of Emphysema

ACE Inhibitors, ARBs Slow Progression of Emphysema

Treatment with full-dose angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers was found to slow disease progression in patients with emphysema.

Mepolizumab for Eosinophilic Granulomatosis Reduces Glucocorticoid Use

Mepolizumab for Eosinophilic Granulomatosis Reduces Glucocorticoid Use

Mepolizumab resulted in longer remission periods with a larger proportion of participants in remission compared to the placebo, which resulted in reduced glucocorticoid use.

ARDS Risk Decreased With Preadmission Corticosteroid Use in Sepsis

ARDS Risk Decreased With Preadmission Corticosteroid Use in Sepsis

Patients with sepsis who received oral corticosteroids before intensive care unit admission were at reduced risk for acute respiratory distress syndrome.

Grass Pollen SLIT Beneficial for Allergic Rhinitis Progression

Grass Pollen SLIT Beneficial for Allergic Rhinitis Progression

Sublingual immunotherapy is associated with slower AR progression and less frequent asthma onset in patients with allergic rhinitis.

Efficacy of Allergen Immunotherapy in Allergic Asthma

Efficacy of Allergen Immunotherapy in Allergic Asthma

Allergen immunotherapy (AIT) was shown to reduce short-term symptoms and medication scores.

Reducing Exacerbations in Moderate-to-Severe COPD With Beta-Blocker Therapy

Reducing Exacerbations in Moderate-to-Severe COPD With Beta-Blocker Therapy

Researchers examined the relationship between COPD and right and left ventricular morphometry to determine which patients may better respond to beta-blocker therapies.

Seqirus Influenza Vaccine Safe, Effective in Children

Seqirus Influenza Vaccine Safe, Effective in Children

Over 2278 health subjects were included in a multicenter study of the Seqirus IIV4 quadrivalent inactivated influenza vaccine.

Hyper- vs Normobaric Oxygen Therapy To Reduce Mortality in Carbon Monoxide Poisoning

Hyper- vs Normobaric Oxygen Therapy To Reduce Mortality in Carbon Monoxide Poisoning

Hyperbaric oxygen therapy reduced the risk for short- and long-term mortality in patients younger than 20 who had carbon monoxide poisoning.

Imatinib Effective in Treating Severe Refractory Asthma

Imatinib Effective in Treating Severe Refractory Asthma

Imatinib demonstrated an improvement in mast-cell activity and airway hyperresponsiveness in severe refractory asthma vs placebo.

Does Benralizumab Effectively Reduce Glucocorticoid Doses in Asthma?

Does Benralizumab Effectively Reduce Glucocorticoid Doses in Asthma?

Researchers compared 4- and 8-week benralizumab vs placebo for asthma.

Home Oxygen Services Subpar for Patients With Lung Disease

Home Oxygen Services Subpar for Patients With Lung Disease

A new survey shows that home oxygen services create barriers for patients with lung disease.

Bronchial Thermoplasty Effective in Severe, Persistent Asthma

Bronchial Thermoplasty Effective in Severe, Persistent Asthma

Compared to the year prior to bronchial thermoplasty (BT) treatment, in the 2 years after BT treatment, patients experienced reduction in severe exacerbations, hospitalizations, and ER visits.

FDA Expands Approved Use of Ivacaftor for Cystic Fibrosis

FDA Expands Approved Use of Ivacaftor for Cystic Fibrosis

The FDA has expanded the approved indication of ivacaftor for cystic fibrosis, increasing the number of rare gene mutations the drug may be used to treat.

Triple Therapy Superior to Long-acting Muscarinic Antagonist for COPD

Triple Therapy Superior to Long-acting Muscarinic Antagonist for COPD

The TRINITY study reports the significant benefits to extafine triple therapy taken in a single inhaler compared with tiotropium in chronic obstructive pulmonary disease.

Roflumilast Reduces Rate of COPD Exacerbations

Roflumilast Reduces Rate of COPD Exacerbations

Simulated studies were key to the approval of roflumilast for reducing COPD exacerbations.

Mepolizumab Improves Quality of Life in Severe Eosinophilic Asthma

Mepolizumab Improves Quality of Life in Severe Eosinophilic Asthma

Mepolizumab showed early and sustained clinically relevant improvements in quality of life, with a good safety profile in severe eosinophilic asthma.

Increase Pneumonia Risk in Asthma With Inhaled Corticosteroids Use

Increase Pneumonia Risk in Asthma With Inhaled Corticosteroids Use

Patients with asthma have an increased risk of pneumonia when using inhaled corticosteroids, including budesonide and fluticasone.

Risk of Adverse Effects in Asthma Increases With Oral Corticosteroids

Risk of Adverse Effects in Asthma Increases With Oral Corticosteroids

Oral corticosteroids, regardless of dose or duration, may increase the risk of adverse effects in patients with severe asthma.

Utibron Neohaler Available for Maintenance Treatment of COPD

Utibron Neohaler Available for Maintenance Treatment of COPD

Sunovion announces Utibron Neohaler, an inhalation powder for the long term maintenance treatment of airflow obstruction in COPD patients.

New Guidelines Released for Treating Patients With COPD Exacerbations

New Guidelines Released for Treating Patients With COPD Exacerbations

The European Respiratory Society and the American Thoracic Society released clinical guidelines for the treatment of patients with chronic obstructive pulmonary disease exacerbations.

Amoxicillin vs Macrolide: Antibiotic Prescribing Habits in Children With CAP

Amoxicillin vs Macrolide: Antibiotic Prescribing Habits in Children With CAP

Despite current guidelines recommending amoxicillin in most children with community-acquired pneumonia (CAP), macrolides and broad-spectrum antibiotics continue to be prescribed for outpatient CAP.

Anatomic Location of Thrombus Not Affected Outcomes of Surgical Pulmonary Embolectomy

Anatomic Location of Thrombus Not Affected Outcomes of Surgical Pulmonary Embolectomy

Patients with either central or peripheral pulmonary embolism had positive outcomes with surgical pulmonary embolectomy for peripheral distribution of thrombus.

Budesonide/Formoterol Treatment for Reducing COPD Exacerbations

Budesonide/Formoterol Treatment for Reducing COPD Exacerbations

Patients with moderate-to-very-severe chronic obstructive pulmonary disease (COPD) had decreased exacerbations after 3 months of commencing budesonide/formoterol treatment.

Switching From IV-to-Oral Antibiotics Safe in Healthcare-Associated Pneumonia

Switching From IV-to-Oral Antibiotics Safe in Healthcare-Associated Pneumonia

Switching from intravenous to oral antibiotics in patients with healthcare-associated pneumonia was found to be safe.

Long-Term Oxygen Therapy Beneficial in COPD with Moderate Desaturation?

Long-Term Oxygen Therapy Beneficial in COPD with Moderate Desaturation?

Long-term supplemental oxygen does not provide any benefit for patients with stable chronic obstructive pulmonary disease regarding time of death or first hospitalization.

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