Statins have anti-inflammatory and anti-oxidative effects, which could reduce exacerbations of both asthma and chronic obstructive pulmonary disease.
Adult caretaker influenza vaccination cocooning programs can prove beneficial and financially successful in private practice models where external funding is limited or not available.
Triple therapy with fluticasone furoate, umeclidinium, and vilanterol was associated with a lower rate of exacerbations in chronic obstructive pulmonary disease.
During the cold and flu season, the use and over-dosing of paracetamol is common, and may partially be driven by higher use of over-the-counter combination medications for the treatment of upper respiratory cold/flu symptoms.
Both chest tube placement and needle aspiration were considered acceptable treatments for primary spontaneous pneumothorax.
Nivolumab plus ipilimumab linked to better survival in NSCLC with high tumor mutational burden.
No significant benefit of long-acting muscarinic antagonists over long-acting beta-agonists in reducing exacerbation risk in uncontrolled, persistent asthma
Adjunct long-acting muscarinic antagonist (LAMA) use with corticosteroids was associated with reduced exacerbation risk compared with placebo in patients with uncontrolled, persistent asthma. However, LAMA, long-acting beta-agonist (LABA), and inhaled corticosteroids (triple therapy) were not associated with lower risk for exacerbations compared with LABA and inhaled corticosteroids alone.
Balanced crystalloids decreases adverse kidney events compared to saline among critically ill patients: The SMART trial
Use of balanced crystalloids (lactated Ringers or Plasma-Lyte A) was associated with a significant reduction in acute kidney injury events compared with normal saline among intensive care unit (ICU) patients. Use of balanced crystalloids was also associated with lower though nonsignificant in-hospital mortality at 30-days after admission.
Continuous positive airway pressure (CPAP) remains the mainstay of medical treatment for OSA.
Treating chronic obstructive pulmonary disease remains challenging, particularly in terms of choosing the appropriate fixed-dose combination bronchodilator.
Bedaquiline and delamanid were effective and well tolerated in patients with multidrug-resistant tuberculosis.
Prescribers tend to favor a frequency of 3 times per day for oral treprostinil dosing in patients with pulmonary arterial hypertension.
RP5063 is a new chemical entity with a novel mechanism of multimodal modulation of serotonin and dopamine signaling pathways.
Early intervention in the case of respiratory compromise in patients with multiple sclerosis has the potential to prevent infection and maintain pulmonary function.
In patients with persistent asthma, single maintenance and reliever therapy was associated with a lower risk for exacerbations compared with inhaled corticosteroids as controller therapy and short-acting beta-agonists as relief therapy.
The risk for death in patients with community-acquired pneumonia who were given mechanical ventilation does not seem to be affected by the presence of acute respiratory distress syndrome.
Tai chi found to be as effective as pulmonary rehabilitation for patients with chronic obstructive pulmonary disease.
Researchers found stronger negative associations for participants with polypharmacy between the ages of 60 and 64 years and at 69 years.
It is still not known whether differences in mortality rates between patients who receive noninvasive vs invasive ventilation for acute exacerbations of COPD can be attributed to less severe disease or other factors.
Regardless of blood eosinophil count, omalizumab was an effective treatment in adult and pediatric patients with severe allergic asthma.