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Breathing New Life Into COPD and Asthma Therapy With Statins

Breathing New Life Into COPD and Asthma Therapy With Statins

Statins have anti-inflammatory and anti-oxidative effects, which could reduce exacerbations of both asthma and chronic obstructive pulmonary disease.

Adult Caregivers Likely to Receive Influenza Vaccination From Pediatric Clinics

Adult Caregivers Likely to Receive Influenza Vaccination From Pediatric Clinics

Adult caretaker influenza vaccination cocooning programs can prove beneficial and financially successful in private practice models where external funding is limited or not available.

Triple Therapy Tied to Reduced Rate of COPD Exacerbations

Triple Therapy Tied to Reduced Rate of COPD Exacerbations

Triple therapy with fluticasone furoate, umeclidinium, and vilanterol was associated with a lower rate of exacerbations in chronic obstructive pulmonary disease.

Paracetamol Overuse During Cold and Flu Season

Paracetamol Overuse During Cold and Flu Season

During the cold and flu season, the use and over-dosing of paracetamol is common, and may partially be driven by higher use of over-the-counter combination medications for the treatment of upper respiratory cold/flu symptoms.

Chest Tube Placement vs Needle Aspiration for Spontaneous Pneumothorax

Chest Tube Placement vs Needle Aspiration for Spontaneous Pneumothorax

Both chest tube placement and needle aspiration were considered acceptable treatments for primary spontaneous pneumothorax.

Adjuvant Pembrolizumab Beneficial in Metastatic NSCLC

Adjuvant Pembrolizumab Beneficial in Metastatic NSCLC

Nivolumab plus ipilimumab linked to better survival in NSCLC with high tumor mutational burden.

No significant benefit of long-acting muscarinic antagonists over long-acting beta-agonists in reducing exacerbation risk in uncontrolled, persistent asthma

Adjunct long-acting muscarinic antagonist (LAMA) use with corticosteroids was associated with reduced exacerbation risk compared with placebo in patients with uncontrolled, persistent asthma. However, LAMA, long-acting beta-agonist (LABA), and inhaled corticosteroids (triple therapy) were not associated with lower risk for exacerbations compared with LABA and inhaled corticosteroids alone.

Balanced crystalloids decreases adverse kidney events compared to saline among critically ill patients: The SMART trial

Use of balanced crystalloids (lactated Ringers or Plasma-Lyte A) was associated with a significant reduction in acute kidney injury events compared with normal saline among intensive care unit (ICU) patients. Use of balanced crystalloids was also associated with lower though nonsignificant in-hospital mortality at 30-days after admission.

AASM: Medical Marijuana Should Not Be Used to Treat Sleep Apnea

AASM: Medical Marijuana Should Not Be Used to Treat Sleep Apnea

Continuous positive airway pressure (CPAP) remains the mainstay of medical treatment for OSA.

Fixed-Dosed Dual Bronchodilators for COPD: Overview and Clinician Interview

Fixed-Dosed Dual Bronchodilators for COPD: Overview and Clinician Interview

Treating chronic obstructive pulmonary disease remains challenging, particularly in terms of choosing the appropriate fixed-dose combination bronchodilator.

Bedaquiline and Delamanid Effective in Multidrug-Resistant Tuberculosis

Bedaquiline and Delamanid Effective in Multidrug-Resistant Tuberculosis

Bedaquiline and delamanid were effective and well tolerated in patients with multidrug-resistant tuberculosis.

Oral Treprostinil Dosing Characteristics in Pulmonary Arterial Hypertension

Oral Treprostinil Dosing Characteristics in Pulmonary Arterial Hypertension

Prescribers tend to favor a frequency of 3 times per day for oral treprostinil dosing in patients with pulmonary arterial hypertension.

Treatment for Idiopathic Pulmonary Fibrosis Gets Orphan Drug Designation

Treatment for Idiopathic Pulmonary Fibrosis Gets Orphan Drug Designation

RP5063 is a new chemical entity with a novel mechanism of multimodal modulation of serotonin and dopamine signaling pathways.

Respiratory Muscle Training in Multiple Sclerosis: Assessing the Evidence

Respiratory Muscle Training in Multiple Sclerosis: Assessing the Evidence

Early intervention in the case of respiratory compromise in patients with multiple sclerosis has the potential to prevent infection and maintain pulmonary function.

Asthma Exacerbation Risk Lower With SMART Therapy

Asthma Exacerbation Risk Lower With SMART Therapy

In patients with persistent asthma, single maintenance and reliever therapy was associated with a lower risk for exacerbations compared with inhaled corticosteroids as controller therapy and short-acting beta-agonists as relief therapy.

Mortality in Mechanically Ventilated Community-Acquired Pneumonia With or Without ARDS

Mortality in Mechanically Ventilated Community-Acquired Pneumonia With or Without ARDS

The risk for death in patients with community-acquired pneumonia who were given mechanical ventilation does not seem to be affected by the presence of acute respiratory distress syndrome.

Tai Chi Helps Improve Respiratory Function in COPD

Tai Chi Helps Improve Respiratory Function in COPD

Tai chi found to be as effective as pulmonary rehabilitation for patients with chronic obstructive pulmonary disease.

Polypharmacy Linked to Poorer Cognitive, Physical Capability

Polypharmacy Linked to Poorer Cognitive, Physical Capability

Researchers found stronger negative associations for participants with polypharmacy between the ages of 60 and 64 years and at 69 years.

Debating Noninvasive vs Invasive Ventilation in Acute Exacerbations of COPD

Debating Noninvasive vs Invasive Ventilation in Acute Exacerbations of COPD

It is still not known whether differences in mortality rates between patients who receive noninvasive vs invasive ventilation for acute exacerbations of COPD can be attributed to less severe disease or other factors.

Omalizumab Effective in Severe Allergic Asthma, Regardless of Eosinophil Level

Omalizumab Effective in Severe Allergic Asthma, Regardless of Eosinophil Level

Regardless of blood eosinophil count, omalizumab was an effective treatment in adult and pediatric patients with severe allergic asthma.

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