Treatments

Long-Term Inhaled Corticosteroid Use in COPD May Increase Fracture Risk

Long-Term Inhaled Corticosteroid Use in COPD May Increase Fracture Risk

Patients with chronic obstructive pulmonary disease had a modest increased risk for hip and upper extremity fractures when taking long-term, high-dose inhaled corticosteroids.

Influenza Can Be Inactivated Using Far-Ultraviolet C Light

Influenza Can Be Inactivated Using Far-Ultraviolet C Light

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Airborne influenza viruses may be safely and effectively eradicated with continuous low doses of far ultraviolet C light.

COPD-Related Lung Transplantation: How Can We Improve Survival Rates?

COPD-Related Lung Transplantation: How Can We Improve Survival Rates?

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Lung transplantation can improve survival in patients with chronic obstructive pulmonary disease, but several variables can affect the surgery's success.

Shorter pediatric tuberculosis treatment linked to higher completion rates

Children with tuberculosis who received 3 months of directly observed preventive therapy were 25 times more likely to complete their treatment regimen than those who received 9 months of self-administered therapy.

A 56-Year-Old Woman Presents With Upper Respiratory Infection With Mild Fever

A 56-Year-Old Woman Presents With Upper Respiratory Infection With Mild Fever

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A 56-year-old woman who received a heart transplant 1 year ago because of dilated cardiomyopathy now presents with mild fever and generalized weakness.

FDA Approves New CFTR Modulator Therapy for Cystic Fibrosis

FDA Approves New CFTR Modulator Therapy for Cystic Fibrosis

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A new cystic fibrosis transmembrane conductance regulator modulator treatment has been approved by the FDA for use in patients aged 12 years and older.

Neonates With Respiratory Distress Syndrome: Does Inhaled Nitric Oxide Reduce Mortality?

Neonates With Respiratory Distress Syndrome: Does Inhaled Nitric Oxide Reduce Mortality?

Off-label use of inhaled nitric oxide is not associated with reduced mortality in neonates born at 22 to 29 weeks'gestation with RDS.

Obstructive Sleep Apnea: Effectiveness of Oronasal vs Nasal CPAP

Obstructive Sleep Apnea: Effectiveness of Oronasal vs Nasal CPAP

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Oronasal masks may not be as effective as nasal masks for the treatment of obstructive sleep apnea.

Cystic Fibrosis Foundation Recommends CFTR Modulator Therapy in Select Patients

Cystic Fibrosis Foundation Recommends CFTR Modulator Therapy in Select Patients

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CFTR modulator therapy recommended in certain patients with cystic fibrosis.

Antibiotics for Acute Exacerbations in COPD: Comparison of Effectiveness and Tolerability

Antibiotics for Acute Exacerbations in COPD: Comparison of Effectiveness and Tolerability

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Researchers compared the clinical cure and adverse effect rates of multiple antibiotics in the treatment of acute exacerbations in chronic obstructive pulmonary disease.

Invasive Mechanical Ventilation in Severe CAP Increased Mortality Risk

Invasive Mechanical Ventilation in Severe CAP Increased Mortality Risk

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Invasive mechanical ventilation in patients with severe community-acquired pneumonia appeared to increase their mortality risk.

Surgical Monitoring in Chronic Lung Disease Using Biodegradable Sensors

Surgical Monitoring in Chronic Lung Disease Using Biodegradable Sensors

A new biodegradable pressure sensor device may make monitoring patients with chronic lung disease easier during surgery.

Guiding COPD Management Using Airway Branch Variation

Guiding COPD Management Using Airway Branch Variation

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Researchers examined variation in airway branches to determine whether they have an effect on the course of chronic obstructive pulmonary disease.

COPD Exercise Capacity With Long-Acting Bronchodilators

COPD Exercise Capacity With Long-Acting Bronchodilators

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Patients with COPD experienced a weighted mean increase in exercise endurance time following treatment with long-acting bronchodilators.

FDA Approves Avycaz Supplemental NDA for Pneumonia

FDA Approves Avycaz Supplemental NDA for Pneumonia

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The FDA approved the supplemental New Drug Application for Avycaz to treat adults with hospital-acquired or ventilator-associated bacterial pneumonia.

Oral  Prednisolone for the Management of Pediatric Wheezing

Oral Prednisolone for the Management of Pediatric Wheezing

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Children who received oral prednisolone vs placebo for virus-associated wheeze had a shorter length of hospital stay.

ABPA Complicating Asthma: Treatment Responses to Prednisolone vs Itraconazole

ABPA Complicating Asthma: Treatment Responses to Prednisolone vs Itraconazole

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Prednisolone may be a more effective treatment in individuals with acute allergic bronchopulmonary aspergillosis complicated asthma, but with more adverse effects compared with itraconazole.

Asthma Exacerbations in Young Children Alleviated With Tiotropium

Asthma Exacerbations in Young Children Alleviated With Tiotropium

Researchers found that tiotropium was safe and may reduce the risk for exacerbations in young children with asthma.

COPD Study Supports Concomitant Beta-Blocker Use in Moderate to Severe Disease

COPD Study Supports Concomitant Beta-Blocker Use in Moderate to Severe Disease

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Lung function may not differ between individuals who take beta-blockers vs those who do not for moderate to severe chronic obstructive pulmonary disease.

Pulmonary Hypertension Treatments Compared for Safety, Adverse Events

Pulmonary Hypertension Treatments Compared for Safety, Adverse Events

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Individuals treated with riociguat for pulmonary hypertension may have a greater risk for gastrointestinal disorders compared with tadalafil and sildenafil.

Predicting COPD Exacerbations, Treatment Responses via Eosinophil Counts

Predicting COPD Exacerbations, Treatment Responses via Eosinophil Counts

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COPD exacerbation risk and treatment response may be predicted using blood eosinophil counts.

Childhood Wheezing Illness Risk Modified by <i>Lactobacillus</i> Microbiome in RSV

Childhood Wheezing Illness Risk Modified by Lactobacillus Microbiome in RSV

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Nasopharyngeal detection and increased abundance of Lactobacillus during acute respiratory infection with respiratory syncytial virus was associated with a lower risk for childhood wheezing illnesses.

Procalcitonin-Guided Pneumonia Treatment Associated With Improved Outcomes

Procalcitonin-Guided Pneumonia Treatment Associated With Improved Outcomes

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Procalcitonin may decrease mortality rates in patients with acute respiratory infections, including pneumonia.

COPD Continues to Present Screening Challenges, Research Barriers

COPD Continues to Present Screening Challenges, Research Barriers

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No data have demonstrated improved mortality, morbidity, or quality of life as a result of screening for COPD in asymptomatic individuals.

Cardiopulmonary Bypass: First-Ever Anticoagulation Guidelines Released

Cardiopulmonary Bypass: First-Ever Anticoagulation Guidelines Released

Clinical practice guidelines for anticoagulation therapy for cardiopulmonary bypass has been released.

Bronchopulmonary Dysplasia Prevention in Preterm Infants

Bronchopulmonary Dysplasia Prevention in Preterm Infants

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Budesonide may lower the rates of bronchopulmonary dysplasia in preterm infants.

Enteral vs Parenteral Nutrition in Critical Care Requiring Mechanical Ventilation

Enteral vs Parenteral Nutrition in Critical Care Requiring Mechanical Ventilation

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Enteral nutritional support was not clinically superior to parenteral nutritional support in critically ill patients receiving mechanical ventilation.

Evidence for Immunotherapy in Pediatric Asthma Lacking

Evidence for Immunotherapy in Pediatric Asthma Lacking

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Children with allergic asthma do not significantly benefit from subcutaneous or sublingual immunotherapy.

Nebulized Hypertonic Saline vs Normal Saline in Infants With Acute Bronchiolitis

Nebulized Hypertonic Saline vs Normal Saline in Infants With Acute Bronchiolitis

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Nebulized hypertonic saline may decrease length of hospital stay and improve clinical severity scores in infants with acute bronchiolitis.

School-based telemedicine enhances asthma management in children

A school-based telemedicine program with directly observed preventive therapy, when compared to enhanced usual care, led to more symptom-free days and fewer emergency department visits or hospitalizations.

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