Rifampin had a significantly higher rate of treatment completion and fewer drug-related adverse events.
Both 15 mg and 20 mg rifampin doses showed a rapid decline in bacteria in patients with tuberculosis.
In 2017, a Work Group was assembled to conduct a systematic review of 3HP regimen studies published between January 2006 to June 2017, specifically looking at outcomes in children, individuals with HIV/AIDS, and those who self-administered treatment.
The Lancet Respiratory Medicine staged a debate between proponents and opponents of pan-TB regimens to tackle the current suboptimal worldwide management of TB resistance.
Control of active tuberculosis (TB) and a major effort to decrease latent TB infection are both necessary to reduce morbidity and achieve TB elimination in the United States.
Researchers developed an algorithmic approach to diagnosing lung cavitary diseases.
Bedaquiline and delamanid were effective and well tolerated in patients with multidrug-resistant tuberculosis.
Large cavitary lung disease may increase cough frequency that lasts for a longer duration in individuals with tuberculosis.
HIV-positive patients with pulmonary tuberculosis benefited from daily antituberculosis therapy in terms of effectiveness and rifampicin resistance.
Shorter treatment regimens for tuberculosis were associated with increased completion rates and fewer adverse events compared with traditional regimens.
Children with tuberculosis who received 3 months of directly observed preventive therapy were 25 times more likely to complete their treatment regimen than those who received 9 months of self-administered therapy.
Patients with type 2 diabetes treated with sulfonylureas had a higher risk of contracting tuberculosis compared with metformin.
New recommendations suggest that high risk tuberculosis patients with cough should be screened for pulmonary tuberculosis.
Recommendations for testing and treating latent TB infection have been discussed by a representative from the California Department of Public Health.
Self-administered TB therapy should be considered when directly observed therapy is not feasible.
The relationship between negative tuberculin skin test and in-hospital mortality has not been previously studied.
Time to sputum culture conversation was not statistically significant between isoniazid-resistant tuberculosis and isoniazid-suspectible tuberculosis.
While directly observed therapy is standard care in TB, study data confirms the efficacy of this treatment method.
In tuberculosis-endemic areas, computers with deep learning capabilities can be trained to detect the disease in regions that have no radiologists.
Patients with tuberculosis have a higher rate of osteoporosis and osteoporotic fracture.