Oral Allergy Treatments: OTC




ORAL ALLERGY TREATMENTS: OTC
Generic Brand Strength Form Dose
ANTIHISTAMINE
(FIRST GENERATION H1 ANTAGONIST)
chlorphenir
amine maleate
Chlor-Trimeton 4mg tabs Children: <6yrs: not recommended.
6−11yrs: 2mg every 4−6hrs; max 12mg/24hrs.

Adults: 4mg every 4−6hrs; max 24mg/24hrs.
clemastine fumarate 1.34mg tabs Children: <12yrs: not recommended.

Adults: 1.34mg every 12hrs; max 2.68mg/day.
diphenhy
dramine HCl
Benadryl Allergy 25mg caps; tabs;
liq-filled softgels1
Children: <6yrs: Individualize. 6−12yrs:
12.5−25mg every 4−6hrs; max 150mg/day.

Adults: 25−50mg every 4−6hrs; max 300mg/day.
12.5mg/
 
5mL
liq1,2,3,5
PediaCare Children’s Allergy 12.5mg/
 
5mL
liq5 Children: <4yrs: do not use. 4−5yrs: not
recommended.
6−11yrs: 5mL every 4hrs; max 6 doses/24hrs.
ANTIHISTAMINE
(SECOND GENERATION H1 ANTAGONIST
cetirizine Children’s Zyrtec Allergy Syrup 1mg/mL syrup1,3 Adults and Children: Dissolve tabs: May take with or
without water. For doses <5mg: use syrup. <2yrs: not recommended.
2−6yrs: Initially 2.5mg once daily; max 5mg once daily or 2.5mg every 12hrs.
≥6yrs: Initially 5−10mg once daily. ≥65yrs: use dissolve tabs or syrup: 5mg once
daily. Hepatic or renal impairment: Individualize.
Children’s Zyrtec Dissolve Tabs 10mg ODT
Zyrtec 10mg tabs
Zyrtec Liquid
Gels
10mg liq-filled gels Adults and Children: <6yrs: not recommended.
≥6yrs: 10mg once daily. Hepatic or renal impairment: Individualize
fexofenadine HCl Allegra 60mg, 180mg tabs Children: Use Children’s Allegra.

Adults: 180mg once daily or 60mg twice daily. Renal impairment: Initially
60mg once daily.
Children’s Allegra 30mg ODT4,5,6 Adults and Children: <6yrs: not recommended. Take on an empty stomach. Place tab on tongue and allow to disintegrate with or without water. 6–11yrs: 1 tab every 12hrs; max 2 tabs/24hrs. ≥12yrs: 2 tabs every 12hrs; max 4 tabs/24hrs.
30mg/
 
5mL
susp5 Adults and Children: <2yrs: not recommended. 2–11yrs: 5mL every 12hrs; max 10mL/24hrs. ≥12yrs: 10mL every 12hrs; max 20mL/24hrs.
Children’s Fexofenadine Tabs 30mg tabs Adults and Children: <6yrs: not recommended.

6–11yrs: 1 tab every 12hrs; max 2 tabs/24hrs. ≥12yrs: 2 tabs every 12hrs; max 4 tabs/24hrs.
levocetirizine
dihydrochloride
Children’s Xyzal Allergy 24HR 2.5mg/
 
5mL
liq soln5 Adults and Children: <2yrs: not recommended.

2–5yrs: max 1.25mg (2.5mL) once daily in the PM. 6–11yrs: max 2.5mg (5mL) once daily in the PM. ≥12yrs: 2.5mg–5mg (5−10mL) once daily in the PM based on symptom severity. Max: 5mg/day.
Xyzal Allergy 24HR 5mg tabs
loratadine Alavert ODT 10mg ODT4 Adults and Children: <6yrs: not recommended.
≥6yrs: Dissolve on tongue; swallow with or without water. 10mg once daily.
Children’s Claritin 5mg chew tabs Adults and Children: <2yrs: not recommended.
2−5yrs: 5mg once daily. ≥6yrs: 10mg once daily or 5mg twice daily. Hepatic or
renal insufficiency:
See literature. RediTabs: Dissolve on tongue; swallow with or without
water. Liqui‑Gels: Swallow whole.
1mg/mL syrup1,2,3
Claritin 10mg tabs
Claritin Liqui‑Gels 10mg liquid-filled caps
Claritin Reditabs 12-Hour 5mg ODT
Claritin Reditabs 24-Hour 10mg ODT
ANTIHISTAMINE + SYMPATHOMIMETIC
cetirizine HCl/
pseudoephe
drine HCl
Zyrtec-D 12 Hour 5mg/
 
120mg
ext‑rel tabs Children: Not recommended.

Adults: Swallow whole. 1 tab twice daily. Hepatic or renal impairment
(CrCl ≤31mL/min): 1 tab once daily.
fexofenadine HCl/
pseudoephe
drine HCl
Allegra-D 12 Hour 60mg/
 
120mg
ext‑rel tabs Children: Not recommended.

Adults: Swallow whole. Take on an empty stomach. 1 tab twice
daily. Renal impairment: Initially 1 tab once daily.
Allegra‑D 24 Hour 180mg/
 
240mg
ext‑rel tabs Children: Not recommended.

Adults: Swallow whole. Take on an empty stomach. 1 tab once daily.
Renal insufficiency: Not recommended.
loratadine/
pseudoephe
drine sulfate
Alavert D‑12 Hour 5mg/
 
120mg
ext‑rel tabs Children: Not recommended.

Adults: Swallow whole. 1 tab every 12hrs.
Claritin‑D 12 Hour 5mg/
 
120mg
ext‑rel tabs Children: Not recommended.

Adults: Swallow whole. 1 tab every 12hrs. Renal insufficiency
(CrCl <30mL/min):
1 tab once daily.
Claritin‑D 24 Hour 10mg/
 
240mg
ext‑rel tabs Children: Not recommended.

Adults: Swallow whole. 1 tab daily. Renal insufficiency
(CrCl <30mL/min):
1 tab every other day.
NOTES

Key: ext-rel = extended-release;
liq = liquid; ODT = orally disintegrating tablets;
susp = suspension; sust‑rel = sustained-release;

1 dye-free;
2 alcohol-free;
3 sugar-free;
4 contains phenylalanine;
5 contains sodium (see product monograph for sodium content);

6 contains lactose.

Not an inclusive list of medications and/or official indications. Please see drug monograph at www.eMPR.com and/or contact company for full drug labeling.

(Rev. 4/2019)

This article originally appeared on MPR